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Forced vital capacity (FVC)
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chr12:101,575,652-103,101,412
Best TWAS P=2.78e-08 · Best GWAS P=2.74e-10 conditioned to 0.0799
101.6M
101.8M
102M
102.2M
102.4M
102.6M
102.8M
103M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
C12orf48
0.09
0.08
lasso
4
0.07
3.5e-04
5.3
5.6
2.8e-08
0.84
0.05
0.78
TRUE
1
METSIM
Adipose
DRAM1
0.12
0.03
enet
24
0.08
1.1e-12
4.5
5.5
3.9e-08
0.13
0.99
0.00
TRUE
3
The Cancer Genome Atlas
Colon Adenocarcinoma
CCDC53
0.07
0.07
blup
55
0.06
1.3e-04
5.3
-5.6
2.8e-08
-0.75
0.02
0.98
FALSE
4
The Cancer Genome Atlas
Esophageal Carcinoma
CCDC53
0.14
0.08
blup
50
0.08
1.8e-03
4.9
-5.2
1.8e-07
-0.75
0.02
0.87
FALSE
2
YFS
Blood
DRAM1
0.33
0.13
enet
101
0.19
1.6e-58
4.1
5.2
2.5e-07
0.12
1.00
0.00
FALSE