[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr13:49,375,072-51,390,447

Best TWAS P=3.89e-18 · Best GWAS P=4.25e-18 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	8.66	8.7	3.9e-18	0.98	0.01	0.98	TRUE
20	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	7.04	-7.5	7.6e-14	-0.36	0.50	0.46	TRUE
19	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	8.41	-7.1	1.4e-12	-0.22	0.06	0.85	TRUE
24	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	7.05	-6.9	4.6e-12	-0.31	0.29	0.71	TRUE
1	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.37	-5.8	7.8e-09	-0.17	1.00	0.00	TRUE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-0.91	-5.7	1.3e-08	-0.24	0.30	0.70	TRUE
9	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	8.41	-5.4	5.6e-08	-0.18	0.08	0.65	TRUE
23	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	7.08	-8.6	9.0e-18	-0.32	0.36	0.64	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	8.57	8.2	2.9e-16	0.91	0.01	0.96	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	7.05	-7.4	1.6e-13	-0.29	0.82	0.18	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	7.04	-7.4	1.8e-13	-0.25	0.84	0.16	FALSE
22	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	7.02	-7.4	1.9e-13	-0.31	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	8.53	-7.2	4.7e-13	-0.81	0.01	0.99	FALSE
8	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	8.41	-7.0	1.9e-12	-0.24	0.09	0.89	FALSE
12	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	7.04	-6.8	1.1e-11	-0.37	0.04	0.42	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	7.04	-6.3	2.4e-10	-0.27	0.01	0.89	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	7.04	-6.1	9.5e-10	-0.23	0.01	0.98	FALSE
16	GTEx	Heart Atrial Appendage	EBPL	0.17	0.04	lasso	5	0.05	2.2e-03	8.41	-6.1	9.6e-10	-0.17	0.08	0.69	FALSE
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	8.41	-6.1	1.4e-09	-0.22	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	8.41	-5.9	3.3e-09	-0.23	0.00	1.00	FALSE
15	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	7.04	-5.8	5.7e-09	-0.26	1.00	0.00	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	7.05	-5.7	1.0e-08	-0.21	1.00	0.00	FALSE
11	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	7.04	-5.6	2.2e-08	-0.26	0.10	0.24	FALSE
5	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	7.04	-5.5	3.2e-08	-0.34	0.49	0.51	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	8.67	-5.5	4.5e-08	-0.65	0.00	0.46	FALSE
4	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	8.41	-5.3	9.1e-08	-0.20	0.11	0.88	FALSE
17	GTEx	Nerve Tibial	EBPL	0.33	0.09	enet	25	0.27	4.6e-19	7.05	-5.3	1.1e-07	-0.24	0.84	0.16	FALSE
7	GTEx	Brain Cerebellar Hemisphere	EBPL	0.54	0.32	enet	17	0.34	1.2e-09	0.37	-5.3	1.5e-07	-0.16	0.25	0.62	FALSE
13	GTEx	Breast Mammary Tissue (Male)	EBPL	0.20	0.05	enet	6	0.03	7.9e-02	1.64	-5.2	1.8e-07	-0.16	0.04	0.20	FALSE
10	GTEx	Brain Frontal Cortex BA9	EBPL	0.50	0.20	enet	18	0.34	7.0e-10	0.37	-5.2	1.9e-07	-0.18	0.29	0.39	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PHF11	0.05	0.02	bslmm	404	0.02	6.7e-04	-2.01	-5.2	2.0e-07	-0.35	0.49	0.10	FALSE
6	GTEx	Artery Coronary	EBPL	0.48	0.03	enet	99	0.12	9.7e-05	8.41	-5.2	2.2e-07	-0.31	0.10	0.66	FALSE