[Hub]/) : Traits : Forced vital capacity (FVC) :

chr16:80,779,331-82,901,701

Best TWAS P=1.68e-08 · Best GWAS P=1.21e-07 conditioned to 0.418

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MPHOSPH6 0.32 0.14 lasso 4 0.17 3.5e-09 5.3 5.3 1.4e-07 0.98 0.01 0.99 FALSE
2 GTEx Artery Tibial MPHOSPH6 0.36 0.24 enet 9 0.27 1.9e-21 4.8 5.4 7.7e-08 0.96 0.04 0.96 FALSE
3 GTEx Cells Transformed fibroblasts CMIP 0.20 0.05 lasso 6 0.07 1.0e-05 -4.7 -5.6 1.7e-08 -0.25 0.16 0.81 TRUE
4 GTEx Pancreas MPHOSPH6 0.25 0.14 enet 15 0.15 9.2e-07 4.8 5.5 3.4e-08 0.89 0.01 0.99 FALSE
5 GTEx Stomach MPHOSPH6 0.41 0.10 lasso 7 0.09 3.5e-05 4.8 5.2 1.9e-07 0.93 0.02 0.97 FALSE
6 GTEx Testis MPHOSPH6 0.52 0.32 lasso 11 0.35 2.0e-16 4.8 5.2 1.8e-07 0.93 0.02 0.98 TRUE
7 GTEx Thyroid MPHOSPH6 0.31 0.21 lasso 4 0.26 4.7e-20 5.3 5.3 1.0e-07 0.98 0.00 0.99 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH6 0.18 0.16 lasso 3 0.16 5.1e-15 5.1 5.2 2.5e-07 0.94 0.01 0.98 FALSE