Best TWAS P=1.68e-08 · Best GWAS P=1.21e-07 conditioned to 0.418
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | MPHOSPH6 | 0.32 | 0.14 | lasso | 4 | 0.17 | 3.5e-09 | 5.3 | 5.3 | 1.4e-07 | 0.98 | 0.01 | 0.99 | FALSE |
2 | GTEx | Artery Tibial | MPHOSPH6 | 0.36 | 0.24 | enet | 9 | 0.27 | 1.9e-21 | 4.8 | 5.4 | 7.7e-08 | 0.96 | 0.04 | 0.96 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | CMIP | 0.20 | 0.05 | lasso | 6 | 0.07 | 1.0e-05 | -4.7 | -5.6 | 1.7e-08 | -0.25 | 0.16 | 0.81 | TRUE |
4 | GTEx | Pancreas | MPHOSPH6 | 0.25 | 0.14 | enet | 15 | 0.15 | 9.2e-07 | 4.8 | 5.5 | 3.4e-08 | 0.89 | 0.01 | 0.99 | FALSE |
5 | GTEx | Stomach | MPHOSPH6 | 0.41 | 0.10 | lasso | 7 | 0.09 | 3.5e-05 | 4.8 | 5.2 | 1.9e-07 | 0.93 | 0.02 | 0.97 | FALSE |
6 | GTEx | Testis | MPHOSPH6 | 0.52 | 0.32 | lasso | 11 | 0.35 | 2.0e-16 | 4.8 | 5.2 | 1.8e-07 | 0.93 | 0.02 | 0.98 | TRUE |
7 | GTEx | Thyroid | MPHOSPH6 | 0.31 | 0.21 | lasso | 4 | 0.26 | 4.7e-20 | 5.3 | 5.3 | 1.0e-07 | 0.98 | 0.00 | 0.99 | FALSE |
8 | The Cancer Genome Atlas | Thyroid Carcinoma | MPHOSPH6 | 0.18 | 0.16 | lasso | 3 | 0.16 | 5.1e-15 | 5.1 | 5.2 | 2.5e-07 | 0.94 | 0.01 | 0.98 | FALSE |