[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr16:88,030,355-90,172,696

Best TWAS P=2.83e-10 · Best GWAS P=1.88e-08 conditioned to 2.11e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts CHMP1A 0.27 0.06 enet 23 0.11 7.0e-09 4.0 6.3 2.8e-10 0.16 0.60 0.12 TRUE
2 GTEx Uterus SNAI3-AS1 0.47 0.00 enet 13 0.04 5.3e-02 -2.5 5.2 2.2e-07 0.05 0.02 0.31 FALSE
3 GTEx Whole Blood SNAI3-AS1 0.15 0.04 enet 21 0.10 6.7e-10 2.3 6.0 1.9e-09 0.07 0.06 0.90 TRUE
4 METSIM Adipose CHMP1A 0.27 0.05 lasso 9 0.07 1.3e-10 4.0 6.0 1.7e-09 0.13 0.73 0.17 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma DPEP1 0.06 0.01 blup 45 0.03 1.7e-03 4.0 -6.0 1.7e-09 -0.25 0.00 0.68 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZNF276 0.09 0.02 enet 12 0.05 2.3e-05 5.2 -5.7 1.5e-08 -0.26 0.00 0.81 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme SNAI3 0.19 0.06 enet 7 0.12 1.6e-04 3.6 -5.1 2.9e-07 0.03 0.00 0.09 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DPEP1 0.06 0.00 enet 5 0.02 2.5e-03 5.2 -5.9 3.7e-09 -0.27 0.00 0.84 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHMP1A 0.07 0.02 blup 38 0.05 3.5e-06 -2.7 5.4 7.7e-08 0.23 0.14 0.32 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHMP1A 0.18 0.01 enet 11 0.06 3.8e-04 4.0 6.1 1.1e-09 0.14 0.01 0.70 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma CHMP1A 0.07 0.03 blup 37 0.03 1.3e-04 4.0 5.2 1.8e-07 0.23 0.15 0.22 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma FANCA 0.08 0.03 blup 76 0.02 2.1e-03 -4.2 5.2 1.7e-07 0.24 0.00 0.09 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma CHMP1A 0.11 0.09 blup 38 0.08 5.1e-08 -2.7 5.3 1.3e-07 0.19 0.37 0.18 FALSE