Best TWAS P=4.09e-13 · Best GWAS P=3.03e-13 conditioned to 0.854
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTA-85E5.10 | 0.10 | 0.04 | lasso | 9 | 0.03 | 1.9e-03 | 5.6 | -6.1 | 1.4e-09 | -0.29 | 0.72 | 0.03 | TRUE |
| 2 | GTEx | Lung | CTA-85E5.10 | 0.09 | 0.01 | enet | 16 | 0.02 | 2.3e-02 | -4.0 | -5.2 | 2.1e-07 | -0.48 | 0.07 | 0.42 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | HORMAD2 | 0.06 | 0.04 | enet | 10 | 0.07 | 5.7e-07 | 7.2 | -7.3 | 4.1e-13 | -0.94 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 6.5 | -6.0 | 2.6e-09 | -0.78 | 0.01 | 0.99 | TRUE |