TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC)
:
←
chr22:29,707,908-31,171,274
Best TWAS P=4.09e-13 · Best GWAS P=3.03e-13 conditioned to 0.854
29.8M
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
HORMAD2
0.06
0.04
enet
10
0.07
5.7e-07
7.2
-7.3
4.1e-13
-0.94
0.01
0.99
TRUE
1
GTEx
Adipose Subcutaneous
CTA-85E5.10
0.10
0.04
lasso
9
0.03
1.9e-03
5.6
-6.1
1.4e-09
-0.29
0.72
0.03
TRUE
4
The Cancer Genome Atlas
Thyroid Carcinoma
MTMR3
0.21
0.08
blup
72
0.16
2.5e-15
6.5
-6.0
2.6e-09
-0.78
0.01
0.99
TRUE
2
GTEx
Lung
CTA-85E5.10
0.09
0.01
enet
16
0.02
2.3e-02
-4.0
-5.2
2.1e-07
-0.48
0.07
0.42
TRUE