[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr20:61,522,825-62,912,463

Best TWAS P=3.37e-16 · Best GWAS P=4.29e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	8.0	8.2	3.4e-16	0.98	0.01	0.99	TRUE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	8.1	-7.9	1.9e-15	-0.85	0.01	0.95	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	7.8	-7.9	4.0e-15	-0.98	0.01	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	7.8	-7.8	6.1e-15	-0.96	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	LIME1	0.04	0.05	blup	47	0.05	9.0e-06	8.0	7.7	1.3e-14	0.97	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	6.4	7.6	3.7e-14	0.93	0.02	0.88	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNFRSF6B	0.05	0.02	blup	44	0.03	2.9e-03	8.1	7.5	8.2e-14	0.93	0.01	0.75	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	ARFRP1	0.04	0.00	blup	51	0.00	1.3e-01	8.0	-7.4	9.7e-14	-0.81	0.01	0.59	FALSE
12	METSIM	Adipose	TPD52L2	0.03	0.00	bslmm	207	0.02	1.5e-03	-4.7	-7.4	1.1e-13	-0.68	0.02	0.75	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	6.2	6.9	3.9e-12	0.84	0.04	0.51	FALSE
27	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	8.1	6.8	8.8e-12	0.90	0.01	0.64	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	6.1	-6.7	2.3e-11	-0.83	0.05	0.95	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	7.0	6.6	3.8e-11	0.88	0.01	0.81	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	6.4	-6.5	7.0e-11	-0.69	0.06	0.51	FALSE
10	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	4.7	-6.2	6.0e-10	-0.73	0.02	0.78	FALSE
6	GTEx	Cells Transformed fibroblasts	CTD-3184A7.4	0.09	0.00	enet	28	0.00	1.4e-01	4.2	6.2	7.8e-10	0.49	0.02	0.85	FALSE
9	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	6.4	-6.1	1.3e-09	-0.74	0.18	0.77	FALSE
3	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	6.3	6.0	1.6e-09	0.66	0.05	0.94	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	6.4	6.0	2.1e-09	0.75	0.05	0.82	FALSE
2	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	5.8	5.9	2.8e-09	0.65	0.20	0.52	FALSE
11	METSIM	Adipose	DNAJC5	0.03	0.00	blup	201	0.01	2.0e-02	3.9	5.7	1.2e-08	0.60	0.08	0.44	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	6.3	5.7	1.2e-08	0.81	0.05	0.94	FALSE
4	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	6.2	5.7	1.4e-08	0.73	0.11	0.64	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STMN3	0.02	0.02	blup	43	0.02	1.7e-03	6.1	5.5	3.1e-08	0.63	0.01	0.92	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	GMEB2	0.16	0.04	blup	64	0.05	1.0e-02	-2.1	-5.5	3.8e-08	-0.49	0.02	0.20	FALSE
5	GTEx	Breast Mammary Tissue	GMEB2	0.18	0.02	lasso	5	0.06	3.0e-04	6.3	5.5	4.5e-08	0.55	0.14	0.19	FALSE
7	GTEx	Esophagus Mucosa	PRPF6	0.16	0.00	enet	8	0.00	9.6e-01	-4.6	5.4	6.2e-08	0.35	0.05	0.06	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	STMN3	0.07	0.01	blup	41	0.05	4.2e-04	5.8	5.2	2.3e-07	0.57	0.02	0.84	FALSE
8	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	6.2	5.1	2.8e-07	0.62	0.16	0.68	FALSE