[Hub]/) : Traits : Forced vital capacity (FVC) :

chr9:138,403,706-139,836,362

Best TWAS P=6.12e-22 · Best GWAS P=8.01e-20 conditioned to 0.304

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex QSOX2 0.18 0.11 lasso 4 0.10 1.0e-12 7.2 8.9 6.8e-19 -0.70 0.78 0.22 FALSE
2 GTEx Cells Transformed fibroblasts QSOX2 0.40 0.25 enet 11 0.30 5.2e-23 -9.0 9.5 2.6e-21 -0.88 0.00 1.00 FALSE
3 GTEx Esophagus Muscularis QSOX2 0.16 0.07 lasso 4 0.06 1.4e-04 7.1 6.3 2.7e-10 -0.35 0.54 0.02 FALSE
4 GTEx Nerve Tibial QSOX2 0.22 0.12 enet 12 0.17 4.6e-12 6.3 5.9 3.0e-09 -0.44 1.00 0.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma QSOX2 0.05 0.03 blup 32 0.03 2.8e-07 -9.0 9.0 1.5e-19 -0.76 0.00 1.00 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma QSOX2 0.10 0.03 enet 6 0.06 3.4e-07 6.1 8.2 1.6e-16 -0.72 0.01 0.99 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma QSOX2 0.04 0.01 enet 4 0.03 3.6e-04 -9.0 9.3 1.0e-20 -0.85 0.00 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma QSOX2 0.10 0.11 lasso 2 0.10 1.6e-06 -9.0 9.2 4.9e-20 -0.96 0.00 1.00 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma QSOX2 0.06 0.05 lasso 2 0.05 2.5e-06 7.2 9.0 2.7e-19 -0.71 0.02 0.96 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma QSOX2 0.05 0.05 enet 4 0.05 2.7e-06 -9.0 9.6 1.2e-21 -0.90 0.00 1.00 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma QSOX2 0.08 0.07 lasso 4 0.08 1.2e-08 -9.0 9.6 6.1e-22 -0.90 0.00 1.00 TRUE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma QSOX2 0.28 0.01 enet 4 0.05 1.6e-02 -9.0 9.0 1.9e-19 -0.85 0.00 0.65 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma QSOX2 0.06 0.01 blup 32 0.05 1.6e-05 6.1 7.5 5.6e-14 -0.61 0.01 0.84 FALSE