TWAS
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Traits
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Traits
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Forced vital capacity (FVC)
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chr9:135,521,303-137,034,272
Best TWAS P=2.07e-08 · Best GWAS P=2.19e-11 conditioned to 0.0089
135.6M
135.8M
136M
136.2M
136.4M
136.6M
136.8M
137M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
CACFD1
0.26
0.05
enet
25
0.10
5.3e-05
-6.7
-5.6
2.1e-08
0.70
0.00
0.99
TRUE
1
GTEx
Brain Cerebellum
SURF1
0.60
0.24
enet
38
0.44
2.7e-14
-4.1
5.2
1.7e-07
-0.44
0.93
0.07
TRUE
3
The Cancer Genome Atlas
Uterine Corpus Endometrial Carcinoma
ABO
0.23
0.07
blup
44
0.12
4.3e-04
-3.9
-5.2
1.8e-07
0.35
0.00
0.03
TRUE