Best TWAS P=2.07e-08 · Best GWAS P=2.19e-11 conditioned to 0.0089
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | SURF1 | 0.60 | 0.24 | enet | 38 | 0.44 | 2.7e-14 | -4.1 | 5.2 | 1.7e-07 | -0.44 | 0.93 | 0.07 | TRUE |
2 | GTEx | Testis | CACFD1 | 0.26 | 0.05 | enet | 25 | 0.10 | 5.3e-05 | -6.7 | -5.6 | 2.1e-08 | 0.70 | 0.00 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ABO | 0.23 | 0.07 | blup | 44 | 0.12 | 4.3e-04 | -3.9 | -5.2 | 1.8e-07 | 0.35 | 0.00 | 0.03 | TRUE |