Best TWAS P=7.37e-08 · Best GWAS P=3.13e-10 conditioned to 9.86e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hippocampus | WAC-AS1 | 0.29 | 0.01 | enet | 10 | -0.01 | 8.5e-01 | 5.9 | 5.4 | 7.4e-08 | -0.03 | 0.03 | 0.65 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | WAC | 0.21 | 0.29 | lasso | 5 | 0.29 | 5.9e-37 | 5.0 | 5.2 | 1.8e-07 | -0.03 | 0.17 | 0.83 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | WAC | 0.06 | 0.04 | lasso | 3 | 0.03 | 4.2e-04 | 5.0 | 5.3 | 1.1e-07 | -0.03 | 0.02 | 0.88 | FALSE |