[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr10:76,664,253-80,383,574

Best TWAS P=4.28e-09 · Best GWAS P=8.47e-11 conditioned to 0.000419

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-5.2	-5.9	4.3e-09	0.04	0.02	0.97	TRUE
2	GTEx	Artery Aorta	RP13-39P12.3	0.14	0.13	enet	9	0.12	2.2e-07	-5.1	-5.2	2.5e-07	0.01	0.03	0.97	FALSE
3	GTEx	Brain Caudate basal ganglia	C10orf11	0.35	0.27	lasso	4	0.25	9.8e-08	5.2	-5.2	1.5e-07	-0.73	0.47	0.49	FALSE
4	GTEx	Brain Cortex	C10orf11	0.32	0.15	lasso	8	0.21	1.4e-06	5.3	-5.8	7.0e-09	-0.78	0.35	0.60	TRUE
5	GTEx	Breast Mammary Tissue	DLG5	0.15	0.09	lasso	7	0.08	6.7e-05	-5.4	-5.1	2.9e-07	-0.01	0.02	0.96	FALSE
6	GTEx	Cells Transformed fibroblasts	DLG5	0.25	0.18	lasso	11	0.16	2.0e-12	-5.3	-5.2	2.2e-07	0.00	0.02	0.98	FALSE
7	GTEx	Heart Atrial Appendage	DLG5	0.32	0.23	lasso	4	0.24	3.9e-11	-5.4	-5.3	1.0e-07	0.00	0.02	0.98	FALSE
8	GTEx	Heart Left Ventricle	DLG5	0.13	0.10	lasso	4	0.09	1.2e-05	-5.4	-5.4	7.3e-08	0.00	0.03	0.97	FALSE
9	GTEx	Liver	DLG5	0.42	0.31	lasso	5	0.28	2.1e-08	-5.3	-5.3	1.4e-07	0.01	0.02	0.98	FALSE
10	GTEx	Lung	DLG5	0.41	0.38	lasso	8	0.37	7.9e-30	-5.2	-5.2	1.9e-07	-0.01	0.04	0.96	FALSE
11	GTEx	Muscle Skeletal	C10orf11	0.11	0.13	lasso	3	0.12	5.1e-12	5.3	-5.5	3.7e-08	-0.74	0.70	0.30	FALSE
12	GTEx	Nerve Tibial	DLG5	0.51	0.44	lasso	6	0.50	1.4e-39	-5.1	-5.2	2.4e-07	0.00	0.06	0.94	FALSE
13	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-5.3	-5.7	1.2e-08	0.01	0.02	0.97	FALSE
14	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-5.3	-5.8	6.6e-09	0.02	0.02	0.97	FALSE
15	GTEx	Pancreas	DLG5	0.39	0.43	enet	11	0.44	3.5e-20	-5.1	-5.3	1.4e-07	0.00	0.04	0.96	FALSE
16	GTEx	Pancreas	RP13-39P12.3	0.20	0.24	lasso	3	0.23	3.8e-10	-5.2	-5.2	1.9e-07	0.00	0.03	0.97	FALSE
17	GTEx	Pituitary	DLG5	0.45	0.36	lasso	11	0.31	1.9e-08	-5.3	-5.2	1.5e-07	0.00	0.02	0.98	FALSE
18	GTEx	Pituitary	RP13-39P12.3	0.38	0.22	lasso	11	0.17	3.8e-05	-5.3	-5.1	3.0e-07	-0.01	0.02	0.95	FALSE
19	GTEx	Thyroid	DLG5	0.39	0.43	lasso	5	0.43	1.5e-35	-5.2	-5.3	9.3e-08	0.00	0.04	0.96	FALSE
20	GTEx	Thyroid	RP13-39P12.3	0.28	0.30	lasso	8	0.29	3.3e-22	-5.2	-5.2	1.6e-07	0.00	0.04	0.96	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	C10orf11	0.20	0.23	lasso	4	0.23	1.1e-29	5.3	-5.6	2.3e-08	-0.71	0.70	0.30	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	DLG5	0.19	0.17	bslmm	592	0.20	1.5e-24	-5.3	-5.6	2.4e-08	-0.02	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	DLG5	0.08	0.03	blup	116	0.06	2.1e-04	4.1	-5.3	9.4e-08	0.06	0.06	0.91	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	DLG5	0.13	0.08	enet	10	0.10	1.2e-09	-5.7	-5.2	2.2e-07	-0.02	0.00	1.00	FALSE