TWAS
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Traits
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Forced vital capacity (FVC)
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chr10:74,317,852-76,266,883
Best TWAS P=9.85e-08 · Best GWAS P=9.45e-08 conditioned to 1
74.5M
75M
75.5M
76M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
NDST2
0.10
0.09
lasso
14
0.10
5.0e-30
5.3
-5.3
9.9e-08
-0.98
0.01
0.99
TRUE
1
GTEx
Adipose Visceral Omentum
DNAJC9-AS1
0.17
0.00
enet
50
0.02
1.9e-02
2.4
-5.2
2.2e-07
0.01
0.04
0.03
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
CHCHD1
0.02
0.01
lasso
2
0.01
2.5e-03
5.2
5.2
1.7e-07
0.94
0.01
0.94
FALSE