Best TWAS P=9.85e-08 · Best GWAS P=9.45e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | DNAJC9-AS1 | 0.17 | 0.00 | enet | 50 | 0.02 | 1.9e-02 | 2.4 | -5.2 | 2.2e-07 | 0.01 | 0.04 | 0.03 | TRUE |
2 | YFS | Blood | NDST2 | 0.10 | 0.09 | lasso | 14 | 0.10 | 5.0e-30 | 5.3 | -5.3 | 9.9e-08 | -0.98 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CHCHD1 | 0.02 | 0.01 | lasso | 2 | 0.01 | 2.5e-03 | 5.2 | 5.2 | 1.7e-07 | 0.94 | 0.01 | 0.94 | FALSE |