[Hub]/) : Traits : Forced vital capacity (FVC) :

chr10:101,975,269-103,362,569

Best TWAS P=7.11e-09 · Best GWAS P=1.32e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-179B2.2 0.13 0.02 lasso 3 0.03 6.5e-03 5.7 5.5 3.3e-08 0.99 0.01 0.99 FALSE
2 GTEx Artery Aorta RP11-179B2.2 0.16 0.11 lasso 2 0.09 7.6e-06 5.6 5.4 6.8e-08 0.99 0.00 0.99 FALSE
3 GTEx Brain Cerebellum RP11-179B2.2 0.37 0.21 lasso 4 0.20 1.4e-06 5.6 5.8 7.1e-09 0.96 0.01 0.98 TRUE
4 GTEx Brain Frontal Cortex BA9 RP11-179B2.2 0.22 0.15 lasso 2 0.11 7.2e-04 5.6 5.3 9.6e-08 0.98 0.01 0.96 FALSE
5 GTEx Breast Mammary Tissue RP11-179B2.2 0.11 0.09 lasso 2 0.07 1.8e-04 5.7 5.6 2.0e-08 0.96 0.01 0.99 FALSE
6 GTEx Esophagus Muscularis RP11-179B2.2 0.15 0.16 lasso 3 0.16 8.1e-10 5.4 5.4 5.4e-08 0.98 0.01 0.99 FALSE
7 GTEx Heart Left Ventricle RP11-179B2.2 0.15 0.18 enet 2 0.14 4.8e-08 5.6 5.6 1.9e-08 1.00 0.00 1.00 FALSE
8 GTEx Lung RP11-179B2.2 0.18 0.12 lasso 3 0.12 1.7e-09 5.6 5.5 4.4e-08 0.99 0.00 1.00 FALSE
9 GTEx Thyroid RP11-179B2.2 0.18 0.12 lasso 7 0.11 8.3e-09 5.2 5.3 1.1e-07 0.91 0.02 0.97 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SEMA4G 0.04 0.01 blup 52 0.02 1.2e-03 5.1 5.4 6.3e-08 0.83 0.01 0.85 FALSE