[Hub]/) : Traits : Forced vital capacity (FVC) :

chr10:103,527,782-105,275,242

Best TWAS P=3.11e-10 · Best GWAS P=2.27e-07 conditioned to 0.935

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous WBP1L 0.05 0.00 enet 8 0.00 5.3e-01 -5.2 5.2 2.2e-07 -0.87 0.05 0.61 FALSE
2 GTEx Adrenal Gland TMEM180 0.19 0.15 enet 12 0.09 3.5e-04 -4.8 -6.3 3.1e-10 0.82 0.06 0.91 TRUE
3 GTEx Artery Coronary TMEM180 0.14 0.05 enet 13 0.04 2.4e-02 -4.9 -5.7 1.0e-08 0.84 0.06 0.76 FALSE
4 GTEx Esophagus Muscularis SUFU 0.07 0.04 enet 18 0.03 5.2e-03 -4.8 -6.0 2.6e-09 0.78 0.06 0.89 FALSE
5 GTEx Esophagus Muscularis TMEM180 0.23 0.22 enet 19 0.19 1.6e-11 -4.8 -5.1 3.0e-07 0.93 0.05 0.94 FALSE
6 GTEx Heart Atrial Appendage TMEM180 0.42 0.21 enet 35 0.27 2.1e-12 -4.9 -5.9 3.0e-09 0.67 0.07 0.93 FALSE
7 GTEx Heart Left Ventricle TMEM180 0.19 0.17 enet 14 0.17 3.7e-09 -4.9 -5.2 1.8e-07 0.90 0.05 0.95 FALSE
8 GTEx Uterus TMEM180 0.22 0.00 enet 23 0.00 2.6e-01 -4.9 -5.6 1.7e-08 0.64 0.04 0.43 FALSE
9 NTR Blood ACTR1A 0.03 0.03 enet 19 0.03 1.4e-09 -4.8 5.3 9.6e-08 -0.84 0.09 0.91 FALSE