Best TWAS P=1.47e-11 · Best GWAS P=5.23e-10 conditioned to 0.00195
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | SNAI3-AS1 | 0.22 | 0.08 | lasso | 4 | 0.17 | 6.6e-09 | -3.0 | 5.5 | 2.9e-08 | -0.65 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Uterus | SNAI3-AS1 | 0.47 | 0.00 | enet | 13 | 0.04 | 5.3e-02 | -3.0 | 5.5 | 4.5e-08 | -0.59 | 0.03 | 0.38 | FALSE |
| 3 | GTEx | Whole Blood | SNAI3-AS1 | 0.15 | 0.04 | enet | 21 | 0.10 | 6.7e-10 | 2.3 | 6.8 | 1.5e-11 | -0.56 | 0.07 | 0.92 | TRUE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | DPEP1 | 0.06 | 0.01 | blup | 45 | 0.03 | 1.7e-03 | 3.5 | -5.8 | 6.5e-09 | -0.02 | 0.00 | 0.74 | TRUE |
| 5 | The Cancer Genome Atlas | Glioblastoma Multiforme | SNAI3 | 0.19 | 0.06 | enet | 7 | 0.12 | 1.6e-04 | 2.5 | -5.6 | 2.3e-08 | 0.68 | 0.00 | 0.82 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DPEP1 | 0.06 | 0.00 | enet | 5 | 0.02 | 2.5e-03 | 5.3 | -5.6 | 1.9e-08 | 0.04 | 0.00 | 0.87 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CHMP1A | 0.07 | 0.02 | blup | 38 | 0.05 | 3.5e-06 | -2.8 | 5.2 | 1.6e-07 | 0.02 | 0.18 | 0.35 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CHMP1A | 0.18 | 0.01 | enet | 11 | 0.06 | 3.8e-04 | 3.5 | 5.2 | 1.9e-07 | 0.03 | 0.01 | 0.75 | FALSE |