[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr16:88,030,355-89,961,957

Best TWAS P=1.47e-11 · Best GWAS P=5.23e-10 conditioned to 0.00195

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue SNAI3-AS1 0.22 0.08 lasso 4 0.17 6.6e-09 -3.0 5.5 2.9e-08 -0.65 0.01 0.98 FALSE
2 GTEx Uterus SNAI3-AS1 0.47 0.00 enet 13 0.04 5.3e-02 -3.0 5.5 4.5e-08 -0.59 0.03 0.38 FALSE
3 GTEx Whole Blood SNAI3-AS1 0.15 0.04 enet 21 0.10 6.7e-10 2.3 6.8 1.5e-11 -0.56 0.07 0.92 TRUE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma DPEP1 0.06 0.01 blup 45 0.03 1.7e-03 3.5 -5.8 6.5e-09 -0.02 0.00 0.74 TRUE
5 The Cancer Genome Atlas Glioblastoma Multiforme SNAI3 0.19 0.06 enet 7 0.12 1.6e-04 2.5 -5.6 2.3e-08 0.68 0.00 0.82 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DPEP1 0.06 0.00 enet 5 0.02 2.5e-03 5.3 -5.6 1.9e-08 0.04 0.00 0.87 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHMP1A 0.07 0.02 blup 38 0.05 3.5e-06 -2.8 5.2 1.6e-07 0.02 0.18 0.35 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHMP1A 0.18 0.01 enet 11 0.06 3.8e-04 3.5 5.2 1.9e-07 0.03 0.01 0.75 FALSE