Best TWAS P=1.77e-08 · Best GWAS P=2.82e-09 conditioned to 0.0172
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | SOGA2 | 0.17 | 0.08 | lasso | 7 | 0.05 | 1.5e-04 | -5.6 | 5.5 | 3.4e-08 | -0.84 | 0.02 | 0.97 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | SOGA2 | 0.09 | 0.04 | lasso | 6 | 0.04 | 2.1e-06 | -5.6 | 5.6 | 1.8e-08 | -0.80 | 0.01 | 0.99 | TRUE |