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Forced expiratory volume in 1-second (FEV1)
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chr18:8,010,444-9,532,097
Best TWAS P=1.77e-08 · Best GWAS P=2.82e-09 conditioned to 0.0172
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
9.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
SOGA2
0.09
0.04
lasso
6
0.04
2.1e-06
-5.6
5.6
1.8e-08
-0.80
0.01
0.99
TRUE
1
GTEx
Nerve Tibial
SOGA2
0.17
0.08
lasso
7
0.05
1.5e-04
-5.6
5.5
3.4e-08
-0.84
0.02
0.97
FALSE