TWAS hub - SOGA2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Lung	0.1430	0.0476	0.00230	0.092	NA	0.068	NA	0.079	1.7e-07	NA	6.2e-06	NA	1.2e-06
2	GTEx	Nerve Tibial	0.1723	0.0605	0.00630	0.076	NA	0.027	NA	0.051	4.8e-06	NA	4.9e-03	NA	1.5e-04
3	GTEx	Pancreas	0.2100	0.0770	0.00940	-0.006	NA	-0.003	NA	-0.005	6.7e-01	NA	4.6e-01	NA	6.2e-01
4	GTEx	Testis	0.2690	0.0660	0.00011	0.152	NA	0.169	NA	0.171	2.9e-07	NA	5.8e-08	NA	5.1e-08
5	ROSMAP	Brain Pre-frontal Cortex	0.0862	0.0254	0.00042	0.044	0.023	0.034	0.03	0.044	2.5e-06	0.00045	2.9e-05	8.3e-05	2.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4	5
Pain all over the body in last month	9.9	10.6	17.2	-3.2	3.4	4.2	3.7
Lung FEV1/FVC ratio	9.1	46.0	74.9	-7.0	8.7	5.6	8.7
Forced expiratory volume in 1-second (FEV1), Best measure	6.8	21.8	34.4	-5.2	5.7	3.9	5.9
Risk taking	6.7	9.8	14.2	-3.5	3.8	3.2	3.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.4	13.6	23.1	-3.5	4.8	3.1	4.8
Blood clot in the leg (DVT)	6.0	7.8	13.5	-2.8	3.7	2.4	3.4
Lung FVC	5.9	30.3	45.6	-6.1	6.6	5.0	6.8
Forced expiratory volume in 1-second (FEV1)	5.9	19.8	31.7	-4.8	5.5	3.7	5.6
Basal cell carcinoma (self-reported)	5.2	6.1	9.1	-2.7	2.8	3.0	2.6
Alzheimer’s Disease (in father)	4.9	5.3	9.7	2.0	-3.1	-1.9	-3.0
Average weekly beer plus cider intake	4.7	6.8	11.8	-2.7	3.4	2.1	3.3
Deep venous thrombosis (DVT) (self-reported)	4.6	5.9	10.7	-2.3	3.3	2.1	3.0
Number of live births	4.5	6.3	11.2	-3.0	3.3	1.7	2.9
Ever used hormone-replacement therapy (HRT)	3.9	5.0	6.9	-2.3	2.6	2.5	2.5
Peak expiratory flow (PEF)	3.8	8.8	15.8	-3.3	4.0	2.1	3.7
Hair/balding pattern: Pattern 2	3.6	4.6	8.8	-2.2	3.0	1.8	2.4
Leg pain on walking	3.6	4.5	7.2	-1.8	2.7	2.3	2.6
Number of operations (self-reported)	3.6	5.3	8.1	-2.5	2.6	2.4	2.8
Friendships satisfaction	3.4	4.2	6.9	-1.6	2.6	2.5	2.4
Diverticular disease/diverticulitis (self-reported)	3.2	3.9	5.6	-2.4	2.3	1.9	2.2
Forced vital capacity (FVC), Best measure	3.1	11.3	17.1	-3.9	4.0	2.9	4.1
Forced vital capacity (FVC)	3.0	11.4	17.3	-3.7	4.1	3.1	4.2
Frequency of tenseness / restlessness in last 2 weeks	2.9	4.6	8.1	-2.6	2.8	1.6	2.3
Townsend deprivation index at recruitment	2.8	3.9	6.1	-2.5	2.0	2.1	2.2
Maternal smoking around birth	2.7	3.9	5.8	-2.4	2.2	1.8	2.4
Medication: Levothyroxine sodium	2.5	4.3	6.6	-2.1	2.0	2.6	2.5
Migraine (self-reported)	2.4	2.9	5.0	2.2	-1.8	-2.2	-1.4
Hypothyroidism/myxoedema (self-reported)	2.1	4.0	6.9	-1.7	2.4	2.2	2.6
Medication: Seretide 50 evohaler	2.1	2.4	8.2	-0.5	1.2	2.9	1.5
Asthma (self-reported)	2.1	4.1	6.9	2.3	-2.6	-1.5	-2.5
Alcohol drinker status: Never	2.1	2.5	4.6	2.1	-1.2	-2.0	-1.5
Hair/balding pattern: Pattern 3	2.0	2.9	9.2	0.3	-3.0	-1.1	-2.0
Asthma	2.0	3.9	6.7	2.3	-2.6	-1.4	-2.4
Respiratory disease	1.9	4.2	6.8	2.6	-2.5	-1.4	-2.5
Impedance of leg (left)	1.9	9.4	15.6	2.9	-4.0	-2.8	-3.9
Mouth/teeth dental problems: Loose teeth	1.9	2.3	3.4	-1.9	1.8	1.6	1.5
Hypothyroidism (self reported)	1.8	4.1	6.7	-1.5	2.6	2.4	2.5
Medication: Atorvastatin	1.8	2.2	4.6	0.4	-2.2	-1.4	-2.0
Schizophrenia vs Biploar Disorder	1.7	2.3	3.3	-1.8	1.8	1.4	1.8
Worrier / anxious feelings	1.7	3.3	5.0	2.2	-2.1	-1.4	-2.2
Ever had hysterectomy (womb removed)	1.6	1.8	3.4	-1.6	1.8	1.1	1.4
Shortness of breath walking on level ground	1.6	1.9	2.7	-1.7	1.5	1.6	1.5
Happiness	1.5	1.8	2.9	-1.2	1.6	1.5	1.7
Health satisfaction	1.5	2.0	4.7	-2.2	1.5	1.0	1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.1	-0.7	1.2	2.0	1.4
Breast cancer (self-reported)	1.5	1.7	3.0	0.9	-1.7	-1.4	-1.7
Ever depressed for a whole week	1.5	1.8	2.9	1.5	-1.7	-1.1	-1.7
Impedance of leg (right)	1.4	6.8	12.5	2.3	-3.5	-2.2	-3.3
Trunk fat-free mass	1.4	7.9	12.0	-2.8	3.0	3.3	3.5
Trunk predicted mass	1.4	8.1	12.2	-2.8	3.0	3.3	3.5
Medication: Ventolin 100micrograms inhaler	1.4	1.8	4.0	0.6	-2.0	-1.0	-1.9
Comparative body size at age 10	1.4	3.8	6.3	-2.0	2.5	1.9	2.3
Family relationship satisfaction	1.4	1.7	2.6	-1.1	1.5	1.6	1.5
Whole body water mass	1.4	7.8	12.0	-2.8	3.0	3.1	3.5
Impedance of whole body	1.4	7.1	11.6	2.5	-3.1	-2.8	-3.4
Mean Putamen Volume	1.3	1.5	2.7	1.6	-1.3	-1.3	-1.1
Fasting Glucose	1.3	1.6	2.8	-1.7	1.1	1.4	1.4
Type 2 Diabetes (T2D) (2018)	1.3	2.5	4.0	2.0	-1.7	-1.7	-1.7
Leg fat-free mass (left)	1.3	6.8	10.8	-2.7	2.8	2.8	3.3
Fed-up feelings	1.3	2.3	4.4	-1.3	1.9	1.5	2.1
Leg predicted mass (left)	1.3	6.7	10.7	-2.7	2.8	2.7	3.3
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.3	-1.2	1.5	1.3	1.4
Arm fat-free mass (right)	1.3	6.9	10.0	-2.9	2.6	3.1	3.2
Whole body fat-free mass	1.3	7.6	11.8	-2.8	3.0	3.1	3.4
Ulcerative Colitis	1.2	1.7	4.0	0.7	-1.3	-2.0	-1.6
BMI	1.2	6.8	11.3	-2.1	3.0	3.1	3.4
Impedance of arm (right)	1.2	5.8	9.0	2.4	-2.5	-2.8	-3.0
Prospective memory result	1.2	1.4	3.2	-1.0	1.0	1.8	1.4
Arm predicted mass (right)	1.2	5.9	8.8	-2.6	2.4	2.9	3.0
Supplements: Vitamin C	1.2	1.4	2.3	1.1	-1.5	-1.5	-1.3
Commuting to job workplace: Walk	1.2	1.2	3.7	-1.2	0.6	1.9	0.9
Basal metabolic rate	1.2	6.8	10.9	-2.6	2.8	2.9	3.3
Arm fat-free mass (left)	1.2	5.9	8.8	-2.7	2.2	2.8	3.0
Pack years of smoking	1.2	1.8	5.3	-1.6	0.4	2.3	1.0
Type 2 Diabetes (T2D) (2012)	1.1	1.2	2.1	1.5	-1.0	-1.1	-1.3
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.1	-1.8	1.4	1.3	1.5
Exposure to tobacco smoke at home	1.1	1.2	2.7	0.7	-1.0	-1.4	-1.6
Leg fat-free mass (right)	1.1	6.0	9.5	-2.5	2.8	2.5	3.1
Handedness (chirality/laterality): Left-handed	1.1	1.4	2.7	1.7	-1.1	-1.0	-1.4
Mood swings	1.1	2.0	3.0	-1.3	1.6	1.7	1.7
Leg predicted mass (right)	1.1	6.1	9.6	-2.6	2.8	2.6	3.1
Average weekly champagne plus white wine intake	1.1	1.6	3.1	1.8	-1.2	-1.3	-1.3
Arm predicted mass (left)	1.1	5.8	9.0	-2.6	2.3	2.9	3.0
Alzheimer’s Disease (including proxy)	1.0	1.5	3.5	1.9	-1.1	-1.1	-1.2
Systolic Blood Pressure	1.0	5.0	10.4	3.2	-1.9	-2.0	-2.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.0	1.9	1.4	-0.8	-1.2	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.8	-0.7	1.6	0.9	1.7
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.1	-1.4	1.2	1.0	1.0
Medication: Aspirin	1.0	1.3	2.2	-1.0	1.3	1.5	1.2
Diabetes diagnosed by doctor	1.0	1.7	3.1	1.7	-1.8	-1.0	-1.3
Alcohol drinker status: Previous	1.0	1.1	2.2	-1.0	1.5	0.7	1.4
Bipolar Disorder (2011)	0.9	0.9	2.2	-0.5	1.2	1.5	0.8
Hand grip strength (left)	0.9	2.3	3.3	-1.8	1.5	1.7	1.7
Sensitivity / hurt feelings	0.9	1.5	3.7	0.2	-1.9	-1.0	-1.6
Severe depression (siblings)	0.9	1.0	2.6	-0.8	1.0	0.8	1.6
Impedance of arm (left)	0.9	4.4	7.1	2.0	-2.1	-2.5	-2.7
Prostate Cancer	0.8	1.1	4.0	2.0	-0.6	-0.7	-0.8
Frequency of depressed mood in last 2 weeks	0.8	1.2	1.9	-0.9	1.1	1.3	1.4
Relative age of first facial hair	0.8	1.7	5.4	-2.3	1.3	0.5	1.0
Relative age voice broke	0.8	1.3	2.8	-1.2	1.7	0.9	1.1
Diabetes (self-reported)	0.8	1.2	3.1	1.7	-1.4	-0.4	-0.9
Fluid intelligence score	0.8	1.6	3.9	-0.2	1.3	2.0	1.5
Weight	0.8	3.9	6.8	-1.8	2.0	2.4	2.6
Headache pain in last month	0.8	1.4	3.0	1.2	-0.9	-1.7	-1.3
Pulse rate, automated reading	0.8	2.7	5.4	-2.3	0.7	2.3	1.6
Number of full sisters	0.8	1.0	3.0	-1.7	1.0	0.2	1.0
Back pain experienced in last month	0.8	1.1	2.6	0.4	-1.3	-1.0	-1.6
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.7	-0.1	1.3	1.1	1.3
Medication: Blood pressure	0.8	1.4	2.6	-0.8	1.6	1.5	1.3
Medication: Lisinopril	0.8	1.1	1.8	-1.1	1.1	1.0	1.4
Schizophrenia (2014)	0.7	1.5	3.1	-1.8	0.9	1.5	1.3
Body mass index (BMI)	0.7	2.9	5.9	-1.3	1.8	1.9	2.4
Mouth/teeth dental problems	0.7	1.0	4.6	2.1	-0.2	-0.6	-0.4
Medication: Cholesterol lowering	0.7	1.1	1.5	1.1	-1.2	-1.2	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	2.0	1.4	-0.7	-1.3	-0.8
Eye problems/disorders: None of the above	0.7	0.8	2.1	-1.4	1.2	-0.5	0.6
Age started oral contraceptive pill	0.7	0.9	3.0	-1.7	0.2	1.1	0.5
Body Mass Index (BMI) (2010)	0.6	0.8	1.6	-0.4	1.2	0.8	1.3
Vitamin and mineral supplements	0.6	0.9	1.7	-0.8	1.3	0.7	1.2
Pack years adult smoking proportion	0.6	1.0	3.2	-1.1	-0.1	1.8	0.5
Chronic bronchitis/emphysema (father)	0.6	0.7	1.4	0.8	-0.9	-0.8	-1.2
Waist circumference	0.6	2.4	4.1	-1.4	1.6	1.9	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.6	1.6	-0.8	-0.6	-0.9
Gout (self-reported)	0.6	0.9	1.5	-1.2	0.6	1.0	1.2
Medication: Amlodipine	0.6	0.9	1.8	-0.2	1.3	1.1	1.2
Birth weight	0.6	1.4	3.1	-1.2	1.1	1.7	1.1
Long-standing illness, disability or infirmity	0.6	1.0	2.0	-1.0	1.1	0.9	1.4
Ever had bowel cancer screening	0.6	0.8	1.2	-1.1	0.9	1.1	0.7
Arm fat mass (left)	0.6	2.4	4.8	-1.2	1.6	1.8	2.2
Myopia	0.6	0.9	1.8	-0.3	1.3	0.8	1.3
Depression (Nagel 2018)	0.5	0.8	1.6	-0.6	1.0	1.0	1.3
Schizophrenia (2018)	0.5	1.0	2.1	-0.9	1.0	1.4	1.2
Irritable Bowel Disease (IBD)	0.5	1.2	3.1	0.6	-1.0	-1.8	-1.3
Rheumatoid Arthritis	0.5	0.7	1.2	-0.8	0.8	1.1	1.1
Triglycerides	0.5	0.9	1.8	-1.1	0.8	1.3	0.8
Heel T-Score	0.5	4.2	6.7	-1.9	2.4	2.2	2.6
Diabetes (mother)	0.5	0.6	1.0	0.3	-0.9	-1.0	-1.0
Had other major operations	0.5	0.6	1.6	-0.5	0.5	1.3	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.2	2.0	0.5	-1.4	-1.3	-1.4
Arm fat mass (right)	0.5	2.1	4.3	-1.0	1.5	1.6	2.1
Number of full brothers	0.5	0.6	1.6	-0.1	-0.9	-1.3	-0.9
Wheeze or whistling in the chest in last year	0.5	0.9	2.3	0.6	-1.5	-0.8	-1.1
Pulse wave peak to peak time	0.5	0.5	2.1	-0.1	-0.2	-1.5	-0.7
Neck or shoulder pain in last month	0.5	0.8	2.1	-1.4	0.8	-0.0	1.0
Leg fat mass (right)	0.5	1.8	3.7	-1.2	0.8	1.9	1.7
Eye problems/disorders: Cataract	0.5	0.6	1.7	0.9	-0.3	1.3	0.6
Wears glasses or contact lenses	0.5	0.5	1.8	-0.1	-0.9	-0.3	-1.3
Medication: Bendroflumethiazide	0.5	0.8	1.3	0.9	-0.9	-1.1	-1.1
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.3	-0.1	-0.8	-0.8	-1.2
Fractured/broken bones in last 5 years	0.5	0.6	1.3	0.2	-0.8	-1.2	-1.1
Bipolar Disorder (2018)	0.4	0.6	0.9	0.8	-1.0	-0.6	-0.9
Depressed Affect (Nagel 2018)	0.4	0.8	2.3	-0.2	0.7	1.5	1.0
Crohns Disease (2017)	0.4	0.8	2.1	0.7	-0.7	-1.4	-1.0
Ulcerative Colitis (UC)	0.4	0.7	1.9	0.4	-0.9	-1.4	-0.9
Coronary Artery Disease (CAD)	0.4	0.5	1.2	0.9	-0.4	-1.1	-0.6
Primary Biliary Cirrhosis	0.4	0.6	1.5	0.6	-0.4	-1.2	-1.0
Blood Platelet Count	0.4	5.1	8.1	2.8	-2.5	-2.1	-2.6
Trunk fat mass	0.4	1.7	2.9	-1.2	1.2	1.7	1.7
Falls in the last year	0.4	0.6	1.3	-1.1	0.7	0.7	0.7
Mouth/teeth dental problems: Dentures	0.4	0.7	1.9	-1.4	0.3	0.9	0.8
Pulse wave Arterial Stiffness index	0.4	0.5	1.9	0.1	0.2	1.4	0.7
Medication: Paracetamol	0.4	0.7	1.5	1.2	-0.4	-1.2	-0.6
High blood pressure (siblings)	0.4	0.5	1.0	-0.5	-0.8	-0.9	-1.0
Whole body fat mass	0.4	1.6	2.8	-1.2	1.0	1.6	1.7
Suffer from ‘nerves’	0.4	0.6	2.0	0.3	-0.9	-0.6	-1.4
Osteoarthritis (self-reported)	0.4	0.6	1.3	-1.1	0.9	-0.1	0.8
Medication: Aspirin	0.4	0.6	1.4	-0.4	0.9	1.2	0.8
Hearing aid user	0.4	0.5	0.7	0.7	-0.7	-0.8	-0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.9	-0.7	0.8	0.5	1.0
Irritability	0.4	0.7	1.4	0.5	0.8	1.2	1.1
Leg fat mass (left)	0.4	1.5	3.1	-1.1	0.7	1.8	1.5
Alzheimer’s Disease (in mother)	0.3	0.4	1.2	1.1	0.6	0.1	0.5
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.8	1.3	-0.8	-0.7	-0.9
HbA1C	0.3	0.3	0.6	0.4	0.4	0.8	0.7
HDL Cholesterol	0.3	0.5	1.2	0.4	-0.7	-0.9	-1.1
Chronotype (morning person)	0.3	0.6	1.5	0.3	-1.2	-0.8	-0.9
Medication for hormone replacement therapy	0.3	0.3	0.8	-0.9	0.1	0.9	0.0
Medication: Co-codamol	0.3	0.4	1.3	0.7	0.3	-1.1	0.1
Diabetes (father)	0.3	0.4	1.0	0.6	0.6	0.6	1.0
Hand grip strength (right)	0.3	0.8	1.4	-0.9	1.1	0.8	1.2
Serious illness, injury or assault to yourself	0.3	0.4	1.3	-0.2	1.2	0.0	0.6
Supplements: Glucosamine	0.3	0.4	1.0	-1.0	0.4	0.7	0.5
Alcohol usually taken with meals	0.3	0.5	1.4	1.2	-0.8	-0.3	-0.7
Nervous feelings	0.3	0.6	1.2	-0.1	-0.9	-0.9	-1.1
Had menopause	0.3	0.4	0.8	-0.9	0.9	0.5	0.5
Medication: Ramipril	0.3	0.4	1.3	1.1	-0.7	-0.2	-0.4
Medication: Simvastatin	0.3	0.4	1.8	1.3	-0.1	0.2	-0.0
Arm fat percentage (right)	0.3	1.1	2.5	-0.5	1.2	1.2	1.6
Hip circumference	0.3	1.3	2.8	-0.8	1.1	1.4	1.7
Noisy workplace	0.3	0.3	0.7	-0.6	0.5	0.6	0.8
Length of working week for main job	0.3	0.3	0.9	-0.1	-1.0	0.5	-0.6
Tense / ‘highly strung’	0.3	0.4	0.9	0.2	0.9	0.7	0.9
Loud music exposure frequency	0.3	0.3	0.7	0.5	-0.5	-0.8	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.8	-0.9	0.2	0.9	0.5
Age at first live birth	0.3	0.6	2.3	1.5	-0.3	-0.2	-0.7
Medication: Allopurinol	0.3	0.3	1.0	-1.0	0.2	0.4	0.7
Heart disease (mother)	0.3	0.4	1.1	-0.1	-1.1	-0.6	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.6	0.4	0.5	0.8	0.8
Overall health rating	0.3	0.6	1.3	-0.7	1.1	0.3	1.2
Had major operations	0.3	0.4	1.2	-1.1	0.5	-0.1	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.5	-0.1	1.2	0.3	0.6
Illnesses of siblings: Diabetes	0.3	0.4	1.4	0.4	1.2	0.1	0.6
Smoking status: Previous	0.3	0.4	0.9	0.4	1.0	0.6	0.8
Arm fat percentage (left)	0.3	1.4	2.8	-0.8	1.3	1.3	1.7
Average weekly red wine intake	0.3	0.5	1.8	-0.8	0.1	1.3	0.3
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	-0.1	0.9	0.1	0.9
Smoking status: Current	0.3	0.4	1.0	0.8	-0.3	-1.0	-0.7
Mother’s age at death	0.3	0.3	0.9	0.0	0.9	0.7	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	0.3	-0.6	-0.5	-1.0
High cholesterol (Self-reported)	0.3	0.5	1.5	1.2	-0.8	0.3	-0.7
Reaction Time	0.2	0.4	1.1	1.0	-0.2	-0.6	-0.7
Age at First Birth	0.2	0.3	0.6	0.8	-0.5	0.1	-0.6
Crohns Disease (2012)	0.2	0.3	1.1	0.5	0.5	-1.0	-0.3
Allergy or Eczema	0.2	0.5	1.0	0.5	-0.6	-1.0	-0.9
Average weekly spirits intake	0.2	0.3	0.7	-0.3	0.6	0.4	0.8
Hearing difficulty/problems: Yes	0.2	0.3	0.6	0.7	-0.7	-0.5	-0.3
Angina	0.2	0.2	0.9	0.5	-0.1	-1.0	-0.1
Medication: Metformin	0.2	0.3	0.5	0.7	-0.7	-0.4	-0.4
Current tobacco smoking	0.2	0.4	0.8	0.8	-0.2	-0.9	-0.6
Age when periods started (menarche)	0.2	0.4	1.3	-1.1	0.1	0.5	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.6	0.6	0.5	0.3
Qualifications: CSEs or equivalent	0.2	0.3	0.7	0.4	0.5	0.8	0.5
Multivitamins +/- minerals	0.2	0.2	0.5	0.3	-0.7	0.5	-0.4
Medication: Atenolol	0.2	0.3	0.6	0.8	0.7	0.1	0.4
High blood pressure (mother)	0.2	0.3	0.5	0.3	0.7	0.6	0.6
Hearing difficulty/problems with background noise	0.2	0.3	0.6	0.4	0.4	0.7	0.7
Financial difficulties in last 2 years	0.2	0.2	0.5	-0.4	0.7	-0.1	0.6
Heart attack	0.2	0.3	1.2	1.1	-0.3	0.3	-0.0
Allergy	0.2	0.4	0.8	-0.6	0.9	0.3	0.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.9	0.4	-0.9	-0.5	-0.5
Time employed in main current job	0.2	0.3	0.7	-0.3	-0.6	-0.8	-0.4
Alcohol intake versus 10 years previously	0.2	0.3	1.0	-1.0	0.2	-0.0	0.6
Pulse rate	0.2	0.4	1.5	-1.2	-0.3	0.5	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.4	-0.8	-0.0	-0.5
Depression (self-reported)	0.2	0.3	1.1	1.0	-0.5	0.3	-0.2
Illnesses of mother	0.2	0.3	0.6	-0.7	0.4	0.8	0.5
Hair/balding pattern: Pattern 4	0.2	0.5	0.9	-0.3	0.8	0.9	0.9
Pulse wave reflection index	0.2	0.2	0.8	0.9	-0.1	0.6	-0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.0	1.0	-0.3	0.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.5	-1.2	0.3	-0.1	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	-0.4	0.4	0.9	0.5
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.6	-0.8	0.7	-0.2	0.5
Leg fat percentage (right)	0.2	0.6	1.8	-0.5	0.2	1.4	1.0
Exposure to tobacco smoke outside home	0.2	0.2	0.5	-0.7	-0.1	0.7	0.5
Worry too long after embarrassment	0.2	0.3	0.6	-0.2	-0.8	-0.6	-0.7
Angina (self-reported)	0.2	0.2	0.8	0.6	-0.1	-0.9	0.0
Alcohol intake frequency.	0.2	0.4	1.7	0.0	0.1	-1.3	0.5
Age at last live birth	0.2	0.3	0.7	0.0	0.8	0.5	0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	-0.3	0.6	-0.1	0.9
Loneliness, isolation	0.2	0.2	0.5	0.7	0.6	0.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	-0.2	-0.9	-0.2	-0.8
Medication for cholesterol	0.2	0.3	0.9	0.3	-0.7	-0.9	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.7	0.5	0.8	0.1	0.7
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	-0.9	0.2	0.3	0.8
Eye problems/disorders: Glaucoma	0.2	0.3	1.0	1.0	-0.3	0.5	-0.2
Medication: Paracetamol	0.2	0.3	0.8	0.9	0.3	-0.6	0.2
Commuting to job workplace: Cycle	0.2	0.2	1.0	-1.0	-0.0	0.3	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.7	0.5	-0.1	-0.8	-0.2
Pain experienced in last month	0.2	0.3	0.8	-0.3	0.5	0.9	0.5
Supplements: Calcium	0.2	0.3	0.5	0.7	-0.7	-0.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.3	1.2	-0.1	0.5	0.1
Bipolar Disorder or Schizophrenia	0.1	0.1	0.5	-0.2	0.2	0.7	0.3
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.8	0.9	-0.4	-0.1	-0.5
Worry (Nagel 2018)	0.1	0.3	0.8	0.4	-0.6	-0.5	-0.9
Breast Cancer	0.1	0.3	0.7	-0.4	0.5	0.9	0.6
LDL Cholesterol	0.1	0.2	0.3	-0.4	0.3	0.6	0.4
Neuroticism (2016)	0.1	0.2	0.4	-0.2	0.6	0.5	0.6
Blood Eosinophil Count	0.1	0.5	1.0	-0.7	0.7	1.0	0.8
Blood Red Count	0.1	1.1	1.9	-0.8	1.2	1.2	1.4
Blood White Count	0.1	1.0	1.8	-1.0	1.3	0.9	1.2
Height	0.1	2.4	5.2	-2.1	0.9	2.3	1.3
Waist Hip Ratio (WHR)	0.1	0.4	0.8	-0.5	0.7	0.9	0.5
Cardiovascular Disease	0.1	0.2	0.7	0.4	0.5	-0.9	0.1
Number of treatments/medications taken	0.1	0.1	0.3	0.6	-0.4	-0.1	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.4	-0.7	0.5	-0.1	0.5
Systolic blood pressure, automated reading	0.1	0.2	0.5	0.7	-0.2	0.5	-0.5
Supplements: Zinc	0.1	0.1	0.3	-0.6	-0.2	0.5	-0.1
Trunk fat percentage	0.1	0.4	0.8	-0.5	0.5	0.8	0.9
Taking other prescription medications	0.1	0.1	0.3	0.5	-0.3	-0.1	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.1	-1.0	0.0	0.5	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.6	0.6	-0.6	-0.8	-0.5
Sitting height	0.1	0.8	1.9	-1.1	0.4	1.4	0.9
Number of incorrect matches in round	0.1	0.1	0.4	-0.1	-0.6	-0.3	-0.4
Past tobacco smoking	0.1	0.2	0.4	-0.4	-0.7	-0.3	-0.3
Qualifications: None of the above	0.1	0.1	0.4	-0.5	-0.0	-0.7	0.1
Neuroticism score	0.1	0.3	0.5	0.7	-0.6	-0.4	-0.7
Father’s age at death	0.1	0.1	0.3	-0.1	0.4	0.6	0.2
Lung cancer (father)	0.1	0.2	0.5	0.4	0.7	-0.1	0.4
Standing height	0.1	0.8	1.7	-1.2	0.6	1.3	0.7
Breastfed as a baby	0.1	0.2	0.5	0.5	-0.1	-0.4	-0.7
Birth weight of first child	0.1	0.2	0.6	-0.0	0.4	0.7	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.1	0.6	0.1	0.4
Glaucoma (self-reported)	0.1	0.1	0.1	0.4	0.2	0.2	0.3
Body fat percentage	0.1	0.4	0.7	-0.6	0.3	0.8	0.8
Number of children fathered	0.1	0.1	0.6	-0.3	0.1	0.7	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.6	0.0	-0.1	0.8	0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.6	-0.8	0.1	-0.0	0.2
Medication: Blood pressure	0.1	0.2	0.4	-0.0	0.7	-0.2	0.5
Medication: Ibuprofen	0.1	0.1	0.3	0.6	-0.4	-0.1	-0.4
Comparative height size at age 10	0.1	0.3	0.6	-0.1	0.5	0.8	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.5	-0.0	0.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.5	0.7	-0.5	0.3	-0.1
Knee pain experienced in last month	0.1	0.2	0.6	-0.8	0.1	-0.7	0.1
Hypertension (Self-reported)	0.1	0.3	0.6	-0.5	0.8	-0.3	0.7
Illnesses of father: Heart disease	0.1	0.2	0.5	-0.5	0.3	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.3	0.2	-0.6	-0.6	-0.1
Qualifications: nursing, teaching	0.1	0.2	0.5	0.7	-0.4	0.4	-0.3
Mineral and other dietary supplements	0.1	0.2	0.5	0.7	0.1	-0.5	0.0
Medication: Gliclazide	0.1	0.2	0.6	0.3	-0.2	-0.8	-0.2
Miserableness	0.1	0.2	0.4	0.4	0.3	0.6	0.6
Guilty feelings	0.1	0.2	0.4	-0.0	0.4	0.6	0.6
Ever taken oral contraceptive pill	0.1	0.1	0.4	-0.7	0.0	0.0	0.5
Financial situation satisfaction	0.1	0.1	0.3	-0.6	0.1	0.6	-0.0
Commuting to job workplace: Public transport	0.1	0.1	0.2	0.3	-0.1	-0.4	-0.5
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.5	0.0	0.4	-0.1
Ever smoked	0.1	0.2	0.7	0.8	-0.1	-0.2	-0.5
Leg fat percentage (left)	0.1	0.5	1.6	-0.3	0.1	1.3	0.9
Diastolic blood pressure, automated reading	0.1	0.3	0.7	0.1	0.7	0.8	0.7
Unable to work because of sickness or disability	0.1	0.1	0.5	-0.3	0.7	0.0	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.5	0.3	-0.7	0.0	-0.7
Cholesterol lowering medication	0.1	0.1	0.4	0.0	0.0	0.6	0.1
Neuroticism (Nagel 2018)	0.0	0.1	0.2	0.3	-0.4	0.4	-0.3
Major Depression (MDD)	0.0	0.0	0.0	0.2	-0.2	0.1	0.2
Ovarian Cancer	0.0	0.0	0.0	0.1	0.2	0.0	-0.2
Lupus	0.0	0.0	0.2	-0.1	-0.4	0.2	-0.0
Smoking Status	0.0	0.1	0.2	0.4	0.5	0.0	0.2
Neuroticism	0.0	0.1	0.3	0.1	-0.2	0.5	-0.0
Hair Pigment	0.0	0.5	1.2	-0.4	-1.1	-0.7	-0.9
Tanning	0.0	0.2	0.5	0.7	-0.6	-0.0	-0.3
Average weekly fortified wine intake	0.0	0.0	0.1	0.3	-0.1	-0.0	-0.2
High blood pressure	0.0	0.1	0.3	-0.2	0.5	-0.2	0.5
Stomach or abdominal pain in last month	0.0	0.0	0.1	-0.1	-0.1	0.2	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.4	-0.1	-0.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.2	-0.1	-0.4	0.1	-0.3
Illnesses of siblings	0.0	0.1	0.2	0.4	-0.0	-0.0	0.3
Medication: Lansoprazole	0.0	0.0	0.1	0.2	0.1	-0.3	-0.2
Qualifications: College or University degree	0.0	0.0	0.0	-0.2	0.1	0.0	0.1
Medication: Omeprazole	0.0	0.0	0.2	0.0	0.2	-0.4	0.0
Mean time to correctly identify matches	0.0	0.1	0.5	-0.1	0.7	-0.0	0.1
Chest pain or discomfort	0.0	0.0	0.2	-0.0	-0.4	-0.1	-0.2
Osteoporosis (self-reported)	0.0	0.1	0.2	0.2	0.2	0.4	-0.0
Heart disease (siblings)	0.0	0.0	0.0	0.0	0.2	-0.0	-0.2

Hub : Genes

SOGA2

Models

Trait associations