Best TWAS P=4.83e-10 · Best GWAS P=2.55e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | TP53INP2 | 0.09 | 0.08 | lasso | 1 | 0.07 | 5.6e-06 | 6.0 | 6.0 | 2.6e-09 | 1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | GSS | 0.06 | 0.02 | enet | 25 | 0.04 | 7.7e-04 | 6.0 | 6.0 | 1.8e-09 | 0.68 | 0.03 | 0.90 | FALSE |
| 3 | GTEx | Vagina | CPNE1 | 0.28 | 0.21 | enet | 20 | 0.34 | 1.6e-08 | 3.5 | -5.5 | 4.7e-08 | 0.00 | 0.42 | 0.23 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GGT7 | 0.02 | 0.02 | lasso | 3 | 0.02 | 2.2e-04 | 6.0 | -5.7 | 1.2e-08 | -0.98 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GDF5 | 0.09 | 0.04 | enet | 13 | 0.05 | 2.4e-04 | 5.6 | 6.2 | 4.8e-10 | 0.02 | 0.00 | 0.99 | TRUE |