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Forced expiratory volume in 1-second (FEV1)
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chr20:32,603,830-34,891,416
Best TWAS P=4.83e-10 · Best GWAS P=2.55e-09 conditioned to 1
32.5M
33M
33.5M
34M
34.5M
35M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
GDF5
0.09
0.04
enet
13
0.05
2.4e-04
5.6
6.2
4.8e-10
0.02
0.00
0.99
TRUE
1
GTEx
Artery Tibial
TP53INP2
0.09
0.08
lasso
1
0.07
5.6e-06
6.0
6.0
2.6e-09
1.00
0.00
1.00
TRUE
2
GTEx
Artery Tibial
GSS
0.06
0.02
enet
25
0.04
7.7e-04
6.0
6.0
1.8e-09
0.68
0.03
0.90
FALSE
4
The Cancer Genome Atlas
Breast Invasive Carcinoma
GGT7
0.02
0.02
lasso
3
0.02
2.2e-04
6.0
-5.7
1.2e-08
-0.98
0.00
0.99
FALSE
3
GTEx
Vagina
CPNE1
0.28
0.21
enet
20
0.34
1.6e-08
3.5
-5.5
4.7e-08
0.00
0.42
0.23
FALSE