Best TWAS P=6.24e-10 · Best GWAS P=3.26e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | TSPY26P | 0.13 | 0.00 | lasso | 7 | 0.00 | 5.7e-01 | -3.7 | 5.3 | 9.9e-08 | -0.61 | 0.04 | 0.34 | FALSE |
| 2 | GTEx | Brain Cerebellum | TSPY26P | 0.25 | 0.06 | lasso | 6 | 0.15 | 2.9e-05 | -5.7 | 5.3 | 1.1e-07 | -0.69 | 0.06 | 0.50 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | TSPY26P | 0.07 | 0.05 | lasso | 5 | 0.03 | 1.2e-03 | -6.2 | 6.2 | 6.2e-10 | -0.97 | 0.02 | 0.94 | TRUE |
| 4 | GTEx | Thyroid | C20orf112 | 0.05 | 0.00 | lasso | 5 | 0.00 | 1.4e-01 | -6.2 | 5.5 | 3.4e-08 | -0.87 | 0.04 | 0.73 | FALSE |
| 5 | GTEx | Vagina | RSL24D1P6 | 0.44 | -0.01 | lasso | 13 | 0.00 | 2.5e-01 | -3.5 | 5.7 | 1.3e-08 | -0.68 | 0.03 | 0.54 | FALSE |
| 6 | METSIM | Adipose | KIF3B | 0.03 | 0.02 | bslmm | 357 | 0.01 | 6.4e-03 | -5.7 | -5.2 | 1.7e-07 | 0.70 | 0.01 | 0.94 | FALSE |