[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr20:46,838,455-48,603,940

Best TWAS P=3.66e-14 · Best GWAS P=3.15e-14 conditioned to 0.0179

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARFGEF2	0.09	0.05	lasso	8	0.10	9.2e-13	7.6	-7.6	3.7e-14	-0.83	0.00	1.00	TRUE
10	METSIM	Adipose	ARFGEF2	0.04	0.03	lasso	12	0.02	9.8e-05	7.5	-7.1	1.5e-12	-0.97	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARFGEF2	0.05	0.04	lasso	5	0.05	3.2e-06	7.6	-7.0	2.0e-12	-0.95	0.00	1.00	FALSE
12	NTR	Blood	SNORD12B	0.03	0.05	lasso	8	0.05	1.9e-14	6.5	-7.0	3.6e-12	-0.95	0.11	0.89	FALSE
9	GTEx	Testis	ARFGEF2	0.20	0.20	lasso	7	0.24	5.4e-11	5.3	-6.7	2.2e-11	-0.93	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C20orf199	0.05	0.06	lasso	4	0.06	1.0e-04	6.6	6.6	5.7e-11	0.91	0.00	0.96	FALSE
2	GTEx	Cells Transformed fibroblasts	STAU1	0.08	0.03	lasso	6	0.02	2.3e-02	5.2	6.1	1.3e-09	0.85	0.03	0.91	FALSE
3	GTEx	Colon Sigmoid	CSE1L	0.18	0.12	lasso	11	0.09	4.4e-04	5.8	-5.9	4.7e-09	-0.81	0.14	0.80	FALSE
5	GTEx	Esophagus Mucosa	ZFAS1	0.15	0.01	enet	16	0.01	8.9e-02	6.5	5.6	2.8e-08	0.69	0.07	0.76	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	STAU1	0.01	0.01	blup	54	0.01	6.1e-03	-4.3	-5.5	4.1e-08	-0.45	0.03	0.13	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	ARFGEF2	0.06	0.01	blup	79	0.03	4.2e-04	-3.8	-5.4	6.2e-08	-0.43	0.75	0.05	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CSE1L	0.05	0.07	blup	50	0.07	3.2e-08	5.7	-5.4	6.5e-08	-0.81	0.39	0.61	FALSE
7	GTEx	Skin Sun Exposed Lower leg	CSE1L	0.08	0.03	lasso	2	0.03	9.5e-04	5.8	-5.4	6.7e-08	-0.82	0.34	0.38	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	DDX27	0.08	0.05	lasso	3	0.05	1.9e-05	6.5	5.4	7.3e-08	0.85	0.06	0.90	FALSE
11	NTR	Blood	NCRNA00275	0.07	0.06	lasso	4	0.08	9.7e-25	-2.6	-5.3	9.6e-08	-0.52	1.00	0.00	FALSE
6	GTEx	Lung	CSE1L	0.10	0.09	lasso	5	0.08	6.6e-07	5.3	-5.3	1.0e-07	-0.74	0.45	0.54	FALSE
4	GTEx	Colon Transverse	ARFGEF2	0.11	0.07	enet	12	0.09	2.9e-05	-1.9	-5.3	1.3e-07	-0.80	0.04	0.95	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ZFAS1	0.07	0.03	enet	14	0.05	5.8e-05	6.5	5.2	1.6e-07	0.78	0.18	0.76	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CSE1L	0.03	0.05	lasso	1	0.03	9.3e-05	5.2	-5.2	1.7e-07	-0.76	0.30	0.61	FALSE