Best TWAS P=1.57e-11 · Best GWAS P=4.96e-11 conditioned to 0.386
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | MICAL3 | 0.23 | 0.06 | lasso | 4 | 0.03 | 2.7e-02 | 6.6 | -6.7 | 1.6e-11 | -0.93 | 0.01 | 0.91 | TRUE |
| 2 | GTEx | Thyroid | MICAL3 | 0.18 | 0.13 | enet | 18 | 0.13 | 6.5e-10 | -5.3 | -6.2 | 6.6e-10 | -0.74 | 0.36 | 0.64 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MICAL3 | 0.10 | 0.06 | enet | 14 | 0.04 | 1.5e-03 | 6.4 | -5.4 | 5.8e-08 | -0.80 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MICAL3 | 0.10 | 0.09 | enet | 14 | 0.10 | 1.4e-09 | -5.3 | -5.5 | 3.4e-08 | -0.69 | 0.39 | 0.61 | FALSE |