[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr20:61,636,050-62,912,463

Best TWAS P=2.77e-12 · Best GWAS P=1.56e-11 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFRP1 0.07 0.07 lasso 3 0.06 5.3e-08 6.5 -6.3 2.5e-10 -0.96 0.01 0.99 FALSE
2 METSIM Adipose TPD52L2 0.03 0.00 bslmm 207 0.02 1.5e-03 -4.3 -6.6 5.1e-11 -0.68 0.02 0.75 FALSE
3 YFS Blood LIME1 0.12 0.19 enet 15 0.19 5.3e-59 6.5 6.6 3.1e-11 0.98 0.01 0.99 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC2A4RG 0.03 0.01 blup 48 0.02 2.4e-03 4.9 -5.3 1.5e-07 -0.69 0.06 0.51 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma LIME1 0.02 0.03 blup 47 0.02 6.2e-03 4.8 5.4 8.2e-08 0.84 0.04 0.48 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma TNFRSF6B 0.02 0.01 enet 7 0.01 6.9e-03 4.8 6.0 1.7e-09 0.93 0.02 0.89 FALSE
7 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RTEL1 0.05 0.04 blup 56 0.03 4.2e-03 5.5 5.1 3.0e-07 0.88 0.01 0.81 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TNFRSF6B 0.05 0.02 blup 44 0.03 2.9e-03 6.7 6.0 1.5e-09 0.93 0.01 0.75 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma ARFRP1 0.03 0.02 lasso 2 0.02 1.2e-03 6.5 -6.5 6.9e-11 -0.98 0.01 0.97 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma LIME1 0.04 0.05 blup 47 0.05 9.0e-06 6.5 6.2 5.4e-10 0.97 0.01 0.99 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SLC2A4RG 0.05 0.01 blup 48 0.02 2.0e-03 6.7 -7.0 2.8e-12 -0.85 0.01 0.95 TRUE
12 The Cancer Genome Atlas Prostate Adenocarcinoma ZGPAT 0.05 0.06 lasso 3 0.06 5.5e-07 4.7 -5.3 1.4e-07 -0.83 0.05 0.95 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors LIME1 0.10 0.02 blup 47 0.04 1.5e-02 6.7 5.2 1.5e-07 0.90 0.01 0.64 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma ARFRP1 0.04 0.00 blup 51 0.00 1.3e-01 6.5 -6.3 3.4e-10 -0.81 0.01 0.58 FALSE