[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr2:218,300,530-220,226,393

Best TWAS P=1.15e-12 · Best GWAS P=3.95e-12 conditioned to 1.73e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Adipose Visceral Omentum	PNKD	0.11	0.00	enet	31	0.00	2.3e-01	-4.1	7.1	1.1e-12	-0.20	0.14	0.04	TRUE
12	METSIM	Adipose	CXCR2	0.04	0.00	blup	436	0.02	1.1e-03	-4.7	6.1	8.2e-10	0.03	0.28	0.02	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	RP11-378A13.1	0.44	0.64	bslmm	431	0.64	1.1e-107	-5.0	5.7	1.3e-08	-0.06	1.00	0.00	FALSE
11	METSIM	Adipose	AAMP	0.03	0.00	bslmm	433	0.01	7.1e-03	-4.2	5.6	2.0e-08	-0.06	0.37	0.02	FALSE
4	GTEx	Artery Aorta	TMBIM1	0.17	0.20	enet	29	0.19	1.2e-10	-4.8	5.5	3.2e-08	-0.01	1.00	0.00	FALSE
9	GTEx	Pancreas	RP11-378A13.1	0.29	0.14	enet	24	0.16	4.4e-07	-5.0	5.4	6.9e-08	-0.01	0.98	0.00	FALSE
10	GTEx	Testis	RP11-378A13.1	0.37	0.18	enet	22	0.22	2.7e-10	-4.7	5.3	8.7e-08	0.00	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	TMBIM1	0.17	0.03	enet	31	0.03	1.1e-02	-4.9	5.3	8.8e-08	0.00	0.49	0.03	FALSE
1	GTEx	Adipose Subcutaneous	BCS1L	0.06	0.01	enet	9	0.04	2.3e-04	-3.1	5.3	1.0e-07	-0.01	0.06	0.24	FALSE
7	GTEx	Colon Sigmoid	RP11-378A13.1	0.31	0.33	enet	23	0.34	6.0e-13	-5.0	5.3	1.1e-07	0.00	1.00	0.00	FALSE
8	GTEx	Muscle Skeletal	RP11-378A13.1	0.19	0.27	enet	23	0.31	1.7e-30	-4.9	5.3	1.2e-07	-0.03	1.00	0.00	FALSE
5	GTEx	Breast Mammary Tissue	RP11-378A13.1	0.27	0.26	enet	20	0.30	1.3e-15	-4.8	5.2	2.6e-07	0.00	1.00	0.00	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RP11-378A13.1	0.18	0.14	lasso	6	0.13	4.6e-05	-4.9	5.1	2.8e-07	-0.03	0.40	0.03	FALSE