[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr2:218,300,530-220,226,393

Best TWAS P=1.15e-12 · Best GWAS P=3.95e-12 conditioned to 1.73e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BCS1L 0.06 0.01 enet 9 0.04 2.3e-04 -3.1 5.3 1.0e-07 -0.01 0.06 0.24 FALSE
2 GTEx Adipose Visceral Omentum PNKD 0.11 0.00 enet 31 0.00 2.3e-01 -4.1 7.1 1.1e-12 -0.20 0.14 0.04 TRUE
3 GTEx Adipose Visceral Omentum TMBIM1 0.17 0.03 enet 31 0.03 1.1e-02 -4.9 5.3 8.8e-08 0.00 0.49 0.03 FALSE
4 GTEx Artery Aorta TMBIM1 0.17 0.20 enet 29 0.19 1.2e-10 -4.8 5.5 3.2e-08 -0.01 1.00 0.00 FALSE
5 GTEx Breast Mammary Tissue RP11-378A13.1 0.27 0.26 enet 20 0.30 1.3e-15 -4.8 5.2 2.6e-07 0.00 1.00 0.00 FALSE
6 GTEx Cells EBV-transformed lymphocytes RP11-378A13.1 0.18 0.14 lasso 6 0.13 4.6e-05 -4.9 5.1 2.8e-07 -0.03 0.40 0.03 FALSE
7 GTEx Colon Sigmoid RP11-378A13.1 0.31 0.33 enet 23 0.34 6.0e-13 -5.0 5.3 1.1e-07 0.00 1.00 0.00 FALSE
8 GTEx Muscle Skeletal RP11-378A13.1 0.19 0.27 enet 23 0.31 1.7e-30 -4.9 5.3 1.2e-07 -0.03 1.00 0.00 FALSE
9 GTEx Pancreas RP11-378A13.1 0.29 0.14 enet 24 0.16 4.4e-07 -5.0 5.4 6.9e-08 -0.01 0.98 0.00 FALSE
10 GTEx Testis RP11-378A13.1 0.37 0.18 enet 22 0.22 2.7e-10 -4.7 5.3 8.7e-08 0.00 1.00 0.00 FALSE
11 METSIM Adipose AAMP 0.03 0.00 bslmm 433 0.01 7.1e-03 -4.2 5.6 2.0e-08 -0.06 0.37 0.02 FALSE
12 METSIM Adipose CXCR2 0.04 0.00 blup 436 0.02 1.1e-03 -4.7 6.1 8.2e-10 0.03 0.28 0.02 FALSE
13 ROSMAP Brain Pre-frontal Cortex RP11-378A13.1 0.44 0.64 bslmm 431 0.64 1.1e-107 -5.0 5.7 1.3e-08 -0.06 1.00 0.00 FALSE