TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr3:40,537,829-42,251,329
Best TWAS P=4.93e-08 · Best GWAS P=1.81e-07 conditioned to 1
40.6M
40.8M
41M
41.2M
41.4M
41.6M
41.8M
42M
42.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
CTNNB1
0.30
0.00
lasso
4
0.01
0.1010
5.2
-5.5
4.9e-08
-0.95
0.02
0.56
TRUE
2
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
ULK4
0.12
0.03
blup
256
0.05
0.0019
3.8
5.3
8.6e-08
0.33
0.19
0.16
TRUE