Best TWAS P=4.93e-08 · Best GWAS P=1.81e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 0.1010 | 5.2 | -5.5 | 4.9e-08 | -0.95 | 0.02 | 0.56 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ULK4 | 0.12 | 0.03 | blup | 256 | 0.05 | 0.0019 | 3.8 | 5.3 | 8.6e-08 | 0.33 | 0.19 | 0.16 | TRUE |