TWAS
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Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr3:140,350,567-141,867,638
Best TWAS P=3.82e-12 · Best GWAS P=1.91e-12 conditioned to 1
140.4M
140.6M
140.8M
141M
141.2M
141.4M
141.6M
141.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZBTB38
0.08
0.04
lasso
4
0.03
0.00081
6.9
6.9
3.8e-12
0.95
0.01
0.99
TRUE