Best TWAS P=1.48e-12 · Best GWAS P=1.08e-10 conditioned to 0.00922
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | COPG1 | 0.04 | 0.02 | bslmm | 303 | 0.03 | 7.6e-06 | 4.7 | -5.2 | 1.7e-07 | 0.33 | 0.73 | 0.09 | FALSE |
| 2 | YFS | Blood | H1FX | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-03 | -5.5 | 5.6 | 2.3e-08 | -0.84 | 0.07 | 0.60 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | H1FX | 0.02 | 0.02 | lasso | 5 | 0.03 | 6.5e-07 | 5.0 | 7.1 | 1.5e-12 | -0.62 | 0.09 | 0.88 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | H1FX | 0.02 | 0.00 | blup | 36 | 0.00 | 5.1e-01 | -6.5 | 7.0 | 2.1e-12 | -0.65 | 0.01 | 0.65 | FALSE |