[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr4:686,563-2,058,475

Best TWAS P=9.41e-08 · Best GWAS P=1.75e-06 conditioned to 0.17

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CRIPAK 0.47 0.24 lasso 12 0.31 1.3e-16 -3.9 -5.1 2.9e-07 0.78 0.06 0.66 FALSE
2 GTEx Brain Caudate basal ganglia CRIPAK 0.27 0.00 lasso 2 0.02 9.3e-02 -4.8 -5.2 2.3e-07 0.95 0.00 0.63 FALSE
3 GTEx Brain Cortex CRIPAK 0.34 0.10 lasso 6 0.18 9.5e-06 -3.9 -5.3 1.4e-07 0.73 0.02 0.62 FALSE
4 GTEx Brain Hypothalamus CRIPAK 0.22 0.00 lasso 5 0.01 2.1e-01 -4.8 -5.2 2.3e-07 0.84 0.01 0.35 FALSE
5 GTEx Uterus CRIPAK 0.52 0.34 lasso 3 0.33 1.7e-07 -4.8 -5.2 1.5e-07 0.94 0.00 0.94 FALSE
6 NTR Blood CRIPAK 0.13 0.09 enet 31 0.15 1.5e-46 -4.3 -5.3 9.4e-08 0.72 0.03 0.88 TRUE
7 The Cancer Genome Atlas Skin Cutaneous Melanoma CRIPAK 0.57 0.07 enet 9 0.23 6.7e-07 -3.9 -5.2 2.5e-07 0.51 0.00 0.11 FALSE