Best TWAS P=9.41e-08 · Best GWAS P=1.75e-06 conditioned to 0.17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CRIPAK | 0.47 | 0.24 | lasso | 12 | 0.31 | 1.3e-16 | -3.9 | -5.1 | 2.9e-07 | 0.78 | 0.06 | 0.66 | FALSE |
| 2 | GTEx | Brain Caudate basal ganglia | CRIPAK | 0.27 | 0.00 | lasso | 2 | 0.02 | 9.3e-02 | -4.8 | -5.2 | 2.3e-07 | 0.95 | 0.00 | 0.63 | FALSE |
| 3 | GTEx | Brain Cortex | CRIPAK | 0.34 | 0.10 | lasso | 6 | 0.18 | 9.5e-06 | -3.9 | -5.3 | 1.4e-07 | 0.73 | 0.02 | 0.62 | FALSE |
| 4 | GTEx | Brain Hypothalamus | CRIPAK | 0.22 | 0.00 | lasso | 5 | 0.01 | 2.1e-01 | -4.8 | -5.2 | 2.3e-07 | 0.84 | 0.01 | 0.35 | FALSE |
| 5 | GTEx | Uterus | CRIPAK | 0.52 | 0.34 | lasso | 3 | 0.33 | 1.7e-07 | -4.8 | -5.2 | 1.5e-07 | 0.94 | 0.00 | 0.94 | FALSE |
| 6 | NTR | Blood | CRIPAK | 0.13 | 0.09 | enet | 31 | 0.15 | 1.5e-46 | -4.3 | -5.3 | 9.4e-08 | 0.72 | 0.03 | 0.88 | TRUE |
| 7 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | CRIPAK | 0.57 | 0.07 | enet | 9 | 0.23 | 6.7e-07 | -3.9 | -5.2 | 2.5e-07 | 0.51 | 0.00 | 0.11 | FALSE |