Best TWAS P=4.95e-08 · Best GWAS P=1.31e-08 conditioned to 0.075
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | LRPAP1 | 0.29 | 0.11 | enet | 16 | 0.14 | 7.6e-10 | 4.0 | -5.2 | 2.4e-07 | 0.32 | 0.71 | 0.26 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | DOK7 | 0.22 | 0.10 | lasso | 3 | 0.14 | 9.2e-14 | -5.2 | -5.5 | 4.9e-08 | 0.47 | 0.02 | 0.98 | TRUE |