[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr1:37,270,283-38,731,622

Best TWAS P=9.83e-10 · Best GWAS P=5.71e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNALI1 0.12 0.07 lasso 4 0.14 1.8e-16 2.9 5.6 2.7e-08 -0.75 0.02 0.98 FALSE
2 GTEx Cells Transformed fibroblasts DNALI1 0.24 0.07 lasso 10 0.07 6.0e-06 -5.6 5.9 3.3e-09 -0.98 0.01 0.99 FALSE
3 GTEx Thyroid MEAF6 0.11 0.02 lasso 8 0.01 3.8e-02 -5.6 5.5 4.7e-08 -0.93 0.01 0.98 FALSE
4 METSIM Adipose MEAF6 0.10 0.07 bslmm 452 0.06 6.0e-10 -5.8 5.2 2.0e-07 -0.97 0.00 1.00 FALSE
5 YFS Blood SNIP1 0.17 0.12 bslmm 438 0.17 1.6e-54 -5.8 5.5 3.2e-08 -0.83 0.00 1.00 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma DNALI1 0.06 0.05 enet 5 0.05 1.2e-10 -5.8 5.5 3.2e-08 -0.99 0.00 1.00 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme DNALI1 0.42 0.19 lasso 3 0.18 3.7e-06 -5.8 5.8 5.7e-09 -1.00 0.00 0.99 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DNALI1 0.04 0.00 blup 41 0.01 7.8e-02 -5.8 6.1 1.1e-09 -0.92 0.00 0.94 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNALI1 0.11 0.09 lasso 1 0.09 6.8e-10 -5.8 5.8 5.7e-09 -1.00 0.00 1.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MEAF6 0.11 0.07 lasso 1 0.05 8.2e-07 -5.8 5.8 5.7e-09 -1.00 0.00 1.00 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNALI1 0.12 0.09 lasso 4 0.07 1.1e-04 -5.8 5.8 6.8e-09 -1.00 0.00 0.99 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DNALI1 0.26 0.25 enet 9 0.26 9.4e-29 -5.8 6.0 1.6e-09 -0.99 0.00 1.00 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma DNALI1 0.06 0.03 blup 41 0.04 2.7e-05 -5.3 6.0 2.4e-09 -0.86 0.00 0.99 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DNALI1 0.07 0.05 lasso 4 0.04 1.7e-05 -5.8 6.1 9.8e-10 -0.98 0.00 0.99 TRUE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FHL3 0.08 0.08 lasso 2 0.08 1.4e-09 -5.2 5.4 6.9e-08 -0.10 0.00 1.00 TRUE
16 The Cancer Genome Atlas Pancreatic Adenocarcinoma DNALI1 0.21 0.16 blup 41 0.16 4.1e-07 -5.8 5.7 1.1e-08 -0.95 0.00 1.00 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma DNALI1 0.27 0.12 lasso 5 0.11 3.9e-05 -5.8 5.8 5.7e-09 -1.00 0.00 0.98 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma DNALI1 0.05 0.01 blup 41 0.02 1.5e-03 -5.8 5.4 6.0e-08 -0.76 0.00 0.82 FALSE
19 The Cancer Genome Atlas Soft Tissue Sarcoma DNALI1 0.09 0.01 blup 41 0.02 2.5e-02 -5.8 5.8 5.3e-09 -0.84 0.00 0.79 FALSE
20 The Cancer Genome Atlas Skin Cutaneous Melanoma DNALI1 0.49 0.04 lasso 7 0.31 4.7e-09 -5.3 5.5 3.4e-08 -0.72 0.01 0.97 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors DNALI1 0.17 0.10 blup 41 0.08 1.2e-03 -5.8 5.5 3.2e-08 -0.92 0.00 0.89 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma DNALI1 0.10 0.07 lasso 2 0.07 1.4e-07 -5.8 5.8 6.4e-09 -1.00 0.00 1.00 FALSE