[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr1:37,270,283-38,731,622

Best TWAS P=9.83e-10 · Best GWAS P=5.71e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DNALI1	0.07	0.05	lasso	4	0.04	1.7e-05	-5.8	6.1	9.8e-10	-0.98	0.00	0.99	TRUE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FHL3	0.08	0.08	lasso	2	0.08	1.4e-09	-5.2	5.4	6.9e-08	-0.10	0.00	1.00	TRUE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DNALI1	0.04	0.00	blup	41	0.01	7.8e-02	-5.8	6.1	1.1e-09	-0.92	0.00	0.94	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	DNALI1	0.26	0.25	enet	9	0.26	9.4e-29	-5.8	6.0	1.6e-09	-0.99	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	DNALI1	0.06	0.03	blup	41	0.04	2.7e-05	-5.3	6.0	2.4e-09	-0.86	0.00	0.99	FALSE
2	GTEx	Cells Transformed fibroblasts	DNALI1	0.24	0.07	lasso	10	0.07	6.0e-06	-5.6	5.9	3.3e-09	-0.98	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Soft Tissue Sarcoma	DNALI1	0.09	0.01	blup	41	0.02	2.5e-02	-5.8	5.8	5.3e-09	-0.84	0.00	0.79	FALSE
7	The Cancer Genome Atlas	Glioblastoma Multiforme	DNALI1	0.42	0.19	lasso	3	0.18	3.7e-06	-5.8	5.8	5.7e-09	-1.00	0.00	0.99	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNALI1	0.11	0.09	lasso	1	0.09	6.8e-10	-5.8	5.8	5.7e-09	-1.00	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MEAF6	0.11	0.07	lasso	1	0.05	8.2e-07	-5.8	5.8	5.7e-09	-1.00	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DNALI1	0.27	0.12	lasso	5	0.11	3.9e-05	-5.8	5.8	5.7e-09	-1.00	0.00	0.98	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	DNALI1	0.10	0.07	lasso	2	0.07	1.4e-07	-5.8	5.8	6.4e-09	-1.00	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DNALI1	0.12	0.09	lasso	4	0.07	1.1e-04	-5.8	5.8	6.8e-09	-1.00	0.00	0.99	FALSE
16	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DNALI1	0.21	0.16	blup	41	0.16	4.1e-07	-5.8	5.7	1.1e-08	-0.95	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNALI1	0.12	0.07	lasso	4	0.14	1.8e-16	2.9	5.6	2.7e-08	-0.75	0.02	0.98	FALSE
5	YFS	Blood	SNIP1	0.17	0.12	bslmm	438	0.17	1.6e-54	-5.8	5.5	3.2e-08	-0.83	0.00	1.00	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNALI1	0.06	0.05	enet	5	0.05	1.2e-10	-5.8	5.5	3.2e-08	-0.99	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNALI1	0.17	0.10	blup	41	0.08	1.2e-03	-5.8	5.5	3.2e-08	-0.92	0.00	0.89	FALSE
20	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DNALI1	0.49	0.04	lasso	7	0.31	4.7e-09	-5.3	5.5	3.4e-08	-0.72	0.01	0.97	FALSE
3	GTEx	Thyroid	MEAF6	0.11	0.02	lasso	8	0.01	3.8e-02	-5.6	5.5	4.7e-08	-0.93	0.01	0.98	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	DNALI1	0.05	0.01	blup	41	0.02	1.5e-03	-5.8	5.4	6.0e-08	-0.76	0.00	0.82	FALSE
4	METSIM	Adipose	MEAF6	0.10	0.07	bslmm	452	0.06	6.0e-10	-5.8	5.2	2.0e-07	-0.97	0.00	1.00	FALSE