TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr5:107,390,303-109,224,099
Best TWAS P=7.37e-09 · Best GWAS P=7.45e-08 conditioned to 0.72
107.5M
108M
108.5M
109M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
FER
0.23
0.15
enet
7
0.18
3.3e-10
5.4
5.8
7.4e-09
0.90
0.00
1.00
TRUE
2
GTEx
Artery Tibial
FER
0.14
0.06
enet
7
0.05
7.3e-05
-4.3
5.2
2.4e-07
0.39
0.24
0.72
FALSE