Best TWAS P=9.56e-12 · Best GWAS P=3.17e-14 conditioned to 0.000672
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | LHFPL2 | 0.38 | 0.02 | lasso | 9 | 0.04 | 0.0402 | 2.1 | -5.7 | 1.4e-08 | 0.52 | 0.04 | 0.46 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AP3B1 | 0.02 | 0.00 | blup | 126 | 0.01 | 0.0182 | -7.2 | -6.8 | 9.6e-12 | 0.86 | 0.02 | 0.86 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AP3B1 | 0.05 | 0.02 | blup | 126 | 0.03 | 0.0005 | 3.0 | -6.0 | 1.9e-09 | 0.80 | 0.02 | 0.92 | FALSE |