Best TWAS P=1.6e-08 · Best GWAS P=1.96e-07 conditioned to 0.737
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | GM2A | 0.23 | 0.31 | lasso | 2 | 0.29 | 2.3e-13 | -5.2 | -5.2 | 1.8e-07 | 1.00 | 0 | 1 | FALSE |
| 2 | NTR | Blood | GM2A | 0.52 | 0.36 | enet | 28 | 0.38 | 4.2e-131 | -5.2 | -5.4 | 6.8e-08 | 0.97 | 0 | 1 | FALSE |
| 3 | YFS | Blood | GM2A | 0.61 | 0.32 | enet | 55 | 0.38 | 1.5e-131 | -5.2 | -5.7 | 1.6e-08 | 0.94 | 0 | 1 | TRUE |