TWAS
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Models
Genes
Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr5:149,903,130-151,338,753
Best TWAS P=1.6e-08 · Best GWAS P=1.96e-07 conditioned to 0.737
150M
150.2M
150.4M
150.6M
150.8M
151M
151.2M
151.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
GM2A
0.61
0.32
enet
55
0.38
1.5e-131
-5.2
-5.7
1.6e-08
0.94
0
1
TRUE
2
NTR
Blood
GM2A
0.52
0.36
enet
28
0.38
4.2e-131
-5.2
-5.4
6.8e-08
0.97
0
1
FALSE
1
GTEx
Heart Atrial Appendage
GM2A
0.23
0.31
lasso
2
0.29
2.3e-13
-5.2
-5.2
1.8e-07
1.00
0
1
FALSE