[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr5:156,009,720-157,697,754

Best TWAS P=8.07e-17 · Best GWAS P=9.41e-15 conditioned to 0.00753

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADAM19	0.08	0.02	blup	159	0.03	5.3e-04	-5.8	-8.3	8.1e-17	0.70	0.03	0.82	TRUE
8	GTEx	Muscle Skeletal	ADAM19	0.06	0.02	lasso	4	0.01	1.5e-02	-7.7	-8.3	1.4e-16	0.88	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	ADAM19	0.09	0.03	lasso	4	0.05	2.4e-06	-7.7	-8.1	6.9e-16	0.83	0.01	0.99	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ADAM19	0.07	0.04	lasso	6	0.06	1.2e-05	-5.8	-7.9	2.7e-15	0.80	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	ADAM19	0.05	0.01	blup	159	0.03	9.5e-04	4.4	-7.7	1.0e-14	0.57	0.06	0.22	FALSE
1	GTEx	Adipose Subcutaneous	ADAM19	0.09	0.08	lasso	6	0.05	5.6e-05	-7.6	-7.7	1.4e-14	0.99	0.00	0.99	FALSE
15	METSIM	Adipose	ADAM19	0.08	0.07	lasso	9	0.07	2.5e-10	-7.7	-7.7	1.9e-14	1.00	0.00	1.00	FALSE
2	GTEx	Breast Mammary Tissue	ADAM19	0.11	0.10	lasso	1	0.06	3.6e-04	-7.7	-7.7	2.0e-14	1.00	0.01	0.99	FALSE
4	GTEx	Breast Mammary Tissue (Female)	ADAM19	0.11	0.14	lasso	6	0.10	5.1e-04	-7.7	-7.6	3.2e-14	0.98	0.01	0.92	FALSE
5	GTEx	Cells Transformed fibroblasts	ADAM19	0.16	0.02	enet	17	0.06	3.0e-05	4.2	-7.5	4.9e-14	0.63	0.06	0.93	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	ADAM19	0.10	0.01	lasso	4	0.08	5.2e-05	-5.2	-7.5	8.5e-14	0.75	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ADAM19	0.07	0.00	blup	159	0.02	2.0e-03	3.1	-7.4	1.4e-13	0.49	0.15	0.16	FALSE
13	GTEx	Testis	ADAM19	0.16	0.00	enet	17	-0.01	6.7e-01	-4.1	-7.3	2.3e-13	0.82	0.02	0.89	FALSE
7	GTEx	Esophagus Mucosa	ADAM19	0.14	0.03	enet	19	0.09	2.4e-06	3.1	-6.6	3.4e-11	0.57	0.06	0.90	FALSE
10	GTEx	Ovary	ADAM19	0.32	0.11	lasso	9	0.08	6.5e-03	-4.8	-6.3	2.3e-10	0.65	0.04	0.73	FALSE
14	GTEx	Whole Blood	ADAM19	0.12	0.07	enet	20	0.07	9.8e-07	-5.0	-6.1	1.3e-09	0.57	0.91	0.09	FALSE
3	GTEx	Breast Mammary Tissue (Male)	ADAM19	0.08	0.03	lasso	1	-0.01	7.7e-01	6.0	-6.0	1.5e-09	0.21	0.05	0.21	FALSE
9	GTEx	Nerve Tibial	ADAM19	0.34	0.16	enet	45	0.30	1.2e-21	-4.3	-5.4	5.2e-08	0.78	0.01	0.99	FALSE
6	GTEx	Colon Sigmoid	CYFIP2	0.24	0.26	lasso	5	0.24	6.2e-09	-5.4	-5.4	5.6e-08	0.28	0.98	0.00	FALSE