[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr5:147,012,186-149,338,157

Best TWAS P=2.36e-20 · Best GWAS P=4.32e-25 conditioned to 0.000194

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	HTR4	0.06	0.03	lasso	4	0.03	4.3e-05	9.7	9.2	2.4e-20	0.79	0.01	0.98	TRUE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	FBXO38	0.05	0.02	lasso	2	0.02	4.3e-02	6.1	-8.9	6.5e-19	-0.77	0.04	0.30	TRUE
4	ROSMAP	Brain Pre-frontal Cortex	ABLIM3	0.32	0.34	bslmm	589	0.33	1.1e-43	-5.3	5.4	7.7e-08	-0.02	0.00	1.00	TRUE
6	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FBXO38	0.04	0.04	blup	52	0.04	4.8e-03	6.5	-8.3	1.4e-16	-0.75	0.05	0.14	FALSE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FBXO38	0.02	0.03	enet	2	0.03	1.9e-04	-7.3	-8.1	5.1e-16	-0.76	0.04	0.60	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FBXO38	0.05	0.01	blup	489	0.02	1.5e-03	7.0	-7.8	9.2e-15	-0.72	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Rectum Adenocarcinoma	FBXO38	0.13	0.17	enet	16	0.15	2.3e-04	7.1	-7.4	1.3e-13	-0.65	0.12	0.31	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	FBXO38	0.03	0.02	blup	51	0.02	7.7e-04	6.0	-7.1	1.5e-12	-0.63	0.54	0.08	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	FBXO38	0.06	0.01	enet	7	0.01	3.2e-02	-3.5	-6.8	8.4e-12	-0.59	0.04	0.26	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	FBXO38	0.05	0.01	blup	51	0.02	7.9e-03	-2.0	-6.7	1.6e-11	-0.66	0.05	0.17	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FBXO38	0.03	0.01	enet	6	0.01	5.0e-02	7.4	-6.3	2.3e-10	-0.53	0.08	0.04	FALSE
3	GTEx	Cells Transformed fibroblasts	FBXO38	0.18	0.05	enet	35	0.10	1.1e-07	7.0	-5.9	3.6e-09	-0.60	0.62	0.35	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	SPINK9	0.08	0.07	enet	21	0.07	1.4e-09	6.0	5.9	4.0e-09	0.48	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	FBXO38	0.11	0.02	blup	52	0.04	8.2e-06	7.1	-5.8	6.2e-09	-0.53	0.69	0.08	FALSE