[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr5:147,012,186-149,338,157

Best TWAS P=2.36e-20 · Best GWAS P=4.32e-25 conditioned to 0.000194

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FBXO38 0.05 0.01 blup 489 0.02 1.5e-03 7.0 -7.8 9.2e-15 -0.72 0.02 0.97 FALSE
2 CommonMind Brain Pre-frontal Cortex HTR4 0.06 0.03 lasso 4 0.03 4.3e-05 9.7 9.2 2.4e-20 0.79 0.01 0.98 TRUE
3 GTEx Cells Transformed fibroblasts FBXO38 0.18 0.05 enet 35 0.10 1.1e-07 7.0 -5.9 3.6e-09 -0.60 0.62 0.35 FALSE
4 ROSMAP Brain Pre-frontal Cortex ABLIM3 0.32 0.34 bslmm 589 0.33 1.1e-43 -5.3 5.4 7.7e-08 -0.02 0.00 1.00 TRUE
5 ROSMAP Brain Pre-frontal Cortex SPINK9 0.08 0.07 enet 21 0.07 1.4e-09 6.0 5.9 4.0e-09 0.48 1.00 0.00 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FBXO38 0.04 0.04 blup 52 0.04 4.8e-03 6.5 -8.3 1.4e-16 -0.75 0.05 0.14 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma FBXO38 0.05 0.02 lasso 2 0.02 4.3e-02 6.1 -8.9 6.5e-19 -0.77 0.04 0.30 TRUE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FBXO38 0.02 0.03 enet 2 0.03 1.9e-04 -7.3 -8.1 5.1e-16 -0.76 0.04 0.60 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FBXO38 0.03 0.01 enet 6 0.01 5.0e-02 7.4 -6.3 2.3e-10 -0.53 0.08 0.04 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma FBXO38 0.11 0.02 blup 52 0.04 8.2e-06 7.1 -5.8 6.2e-09 -0.53 0.69 0.08 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma FBXO38 0.03 0.02 blup 51 0.02 7.7e-04 6.0 -7.1 1.5e-12 -0.63 0.54 0.08 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma FBXO38 0.05 0.01 blup 51 0.02 7.9e-03 -2.0 -6.7 1.6e-11 -0.66 0.05 0.17 FALSE
13 The Cancer Genome Atlas Rectum Adenocarcinoma FBXO38 0.13 0.17 enet 16 0.15 2.3e-04 7.1 -7.4 1.3e-13 -0.65 0.12 0.31 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FBXO38 0.06 0.01 enet 7 0.01 3.2e-02 -3.5 -6.8 8.4e-12 -0.59 0.04 0.26 FALSE