TWAS
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Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr5:176,040,488-177,260,129
Best TWAS P=6.41e-08 · Best GWAS P=1.01e-09 conditioned to 0.000157
176M
176.2M
176.4M
176.6M
176.8M
177M
177.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Colon Adenocarcinoma
RAB24
0.08
0.04
enet
7
0.06
3.4e-04
-3.5
5.4
6.4e-08
0.54
0.01
0.28
TRUE
1
CommonMind
Brain Pre-frontal Cortex
RAB24
0.14
0.06
enet
14
0.09
4.2e-11
5.0
5.2
1.6e-07
0.71
0.16
0.84
FALSE
2
GTEx
Heart Atrial Appendage
MXD3
0.33
0.15
enet
24
0.16
1.5e-07
1.5
5.2
1.8e-07
0.29
0.82
0.01
FALSE