[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr6:80,120,201-81,763,771

Best TWAS P=1.9e-09 · Best GWAS P=1.34e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta BCKDHB 0.14 0.14 lasso 1 0.13 9.8e-08 5.4 5.4 7.6e-08 0.90 0.11 0.88 FALSE
2 GTEx Artery Tibial BCKDHB 0.16 0.16 lasso 11 0.15 4.9e-12 5.5 5.3 8.8e-08 0.91 0.08 0.92 FALSE
3 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 6.0 5.7 1.6e-08 0.67 0.01 0.98 FALSE
4 GTEx Colon Transverse RP11-250B2.6 0.15 0.16 lasso 2 0.13 9.8e-07 6.0 -5.8 6.1e-09 -1.00 0.00 1.00 FALSE
5 GTEx Esophagus Muscularis BCKDHB 0.18 0.07 enet 25 0.06 2.4e-04 5.5 5.8 6.4e-09 0.85 0.09 0.90 FALSE
6 GTEx Lung BCKDHB 0.09 0.06 enet 10 0.05 1.8e-04 5.5 5.4 5.3e-08 0.90 0.11 0.87 FALSE
7 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 6.1 -5.5 3.4e-08 -0.80 0.00 1.00 FALSE
8 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 5.4 5.8 5.8e-09 0.92 0.04 0.96 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic RP11-250B2.6 0.08 0.05 lasso 4 0.01 8.1e-02 6.1 -5.6 2.1e-08 -0.94 0.02 0.93 FALSE
10 GTEx Stomach RP11-250B2.6 0.13 0.15 lasso 6 0.12 2.5e-06 6.0 -5.9 3.8e-09 -0.99 0.00 1.00 FALSE
11 GTEx Testis RP11-250B2.6 0.09 0.05 lasso 6 0.04 6.9e-03 6.1 -5.8 5.1e-09 -0.94 0.02 0.96 FALSE
12 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 6.1 5.7 1.1e-08 0.92 0.01 0.99 FALSE
13 GTEx Thyroid RP11-250B2.6 0.11 0.10 lasso 2 0.07 3.2e-06 6.0 -6.0 1.9e-09 -1.00 0.00 1.00 TRUE
14 ROSMAP Brain Pre-frontal Cortex BCKDHB 0.18 0.13 lasso 6 0.14 2.9e-17 5.4 5.1 2.8e-07 0.88 0.12 0.88 FALSE
15 The Cancer Genome Atlas Testicular Germ Cell Tumors BCKDHB 0.19 0.02 blup 137 0.06 2.6e-03 5.5 5.1 2.9e-07 0.78 0.02 0.35 FALSE