TWAS
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About
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Models
Genes
Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr6:116,069,048-117,481,404
Best TWAS P=2.02e-08 · Best GWAS P=6.7e-08 conditioned to 0.0804
116M
116.2M
116.4M
116.6M
116.8M
117M
117.2M
117.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
FAM26F
0.29
0.19
enet
26
0.23
1.9e-17
-5.4
5.6
2.0e-08
-0.76
0.00
1.00
TRUE
3
GTEx
Cells Transformed fibroblasts
RP1-93H18.7
0.08
0.06
enet
8
0.07
3.9e-06
-4.9
-5.2
1.9e-07
0.86
0.02
0.98
FALSE
1
GTEx
Adipose Subcutaneous
RP1-93H18.7
0.11
0.08
lasso
3
0.08
8.1e-07
-5.2
-5.1
3.1e-07
0.88
0.01
0.99
FALSE