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Forced expiratory volume in 1-second (FEV1)
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chr6:125,970,401-127,355,237
Best TWAS P=5.79e-17 · Best GWAS P=1.75e-19 conditioned to 0.000417
126M
126.2M
126.4M
126.6M
126.8M
127M
127.2M
127.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
CENPW
0.04
0.06
blup
35
0.05
9.2e-07
8.1
-8.4
5.8e-17
0.87
0.02
0.98
TRUE
1
CommonMind
Brain Pre-frontal Cortex
CENPW
0.04
0.06
lasso
10
0.06
2.4e-07
8.0
-8.3
1.5e-16
0.89
0.33
0.67
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CENPW
0.04
0.05
lasso
5
0.05
2.6e-06
8.1
-8.2
1.6e-16
0.87
0.02
0.98
FALSE
2
METSIM
Adipose
CENPW
0.02
0.02
blup
189
0.01
8.3e-03
8.1
-6.7
1.6e-11
0.69
0.07
0.27
FALSE