Best TWAS P=5.79e-17 · Best GWAS P=1.75e-19 conditioned to 0.000417
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | 8.0 | -8.3 | 1.5e-16 | 0.89 | 0.33 | 0.67 | FALSE |
| 2 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | 8.1 | -6.7 | 1.6e-11 | 0.69 | 0.07 | 0.27 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | 8.1 | -8.2 | 1.6e-16 | 0.87 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | 8.1 | -8.4 | 5.8e-17 | 0.87 | 0.02 | 0.98 | TRUE |