TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr1:67,814,420-69,212,053
Best TWAS P=5.04e-08 · Best GWAS P=3.94e-07 conditioned to 0.191
67.8M
68M
68.2M
68.4M
68.6M
68.8M
69M
69.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Nerve Tibial
DIRAS3
0.18
0.01
lasso
6
0.05
0.00013
-4.8
5.4
5e-08
-0.78
0.03
0.93
TRUE