TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr6:158,041,511-159,632,250
Best TWAS P=2.17e-10 · Best GWAS P=3.92e-10 conditioned to 0.000664
158M
158.2M
158.4M
158.6M
158.8M
159M
159.2M
159.4M
159.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
TULP4
0.09
0.05
blup
148
0.04
0.00002
5.2
-6.3
2.2e-10
-0.53
0.29
0.64
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
TULP4
0.03
0.03
lasso
3
0.02
0.00511
5.2
-5.3
1.0e-07
-0.61
0.09
0.59
FALSE
1
GTEx
Thyroid
TULP4
0.09
0.02
lasso
4
0.03
0.00144
5.9
5.2
1.8e-07
0.51
0.08
0.54
FALSE