Best TWAS P=2.17e-10 · Best GWAS P=3.92e-10 conditioned to 0.000664
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | TULP4 | 0.09 | 0.02 | lasso | 4 | 0.03 | 0.00144 | 5.9 | 5.2 | 1.8e-07 | 0.51 | 0.08 | 0.54 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 0.00002 | 5.2 | -6.3 | 2.2e-10 | -0.53 | 0.29 | 0.64 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TULP4 | 0.03 | 0.03 | lasso | 3 | 0.02 | 0.00511 | 5.2 | -5.3 | 1.0e-07 | -0.61 | 0.09 | 0.59 | FALSE |