Best TWAS P=3.85e-08 · Best GWAS P=2.68e-06 conditioned to 0.205
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | C1GALT1 | 0.44 | 0.11 | enet | 24 | 0.22 | 8.8e-10 | -4.0 | -5.1 | 2.7e-07 | -0.43 | 0.09 | 0.74 | FALSE |
| 2 | GTEx | Spleen | C1GALT1 | 0.56 | 0.29 | lasso | 6 | 0.46 | 3.2e-13 | -3.9 | -5.5 | 3.9e-08 | -0.69 | 0.05 | 0.81 | TRUE |
| 3 | GTEx | Stomach | C1GALT1 | 0.24 | 0.07 | enet | 17 | 0.12 | 1.9e-06 | -3.9 | -5.3 | 1.3e-07 | -0.48 | 0.12 | 0.63 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | C1GALT1 | 0.24 | 0.13 | lasso | 5 | 0.23 | 4.6e-29 | 3.9 | -5.4 | 5.7e-08 | -0.67 | 0.08 | 0.76 | FALSE |
| 5 | YFS | Blood | C1GALT1 | 0.35 | 0.20 | enet | 45 | 0.32 | 4.3e-109 | -4.3 | -5.5 | 4.3e-08 | -0.67 | 0.04 | 0.89 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | C1GALT1 | 0.08 | 0.03 | blup | 112 | 0.06 | 2.5e-07 | 4.7 | -5.4 | 7.8e-08 | -0.68 | 0.01 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C1GALT1 | 0.04 | 0.00 | blup | 108 | 0.02 | 2.7e-03 | 2.4 | -5.3 | 1.3e-07 | -0.75 | 0.01 | 0.51 | FALSE |