[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr7:22,946,782-24,382,726

Best TWAS P=1.85e-09 · Best GWAS P=1.97e-16 conditioned to 1.05e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes CCDC126 0.52 0.39 enet 26 0.40 3.0e-14 -6.0 -6.0 1.9e-09 0.40 1.00 0.00 TRUE
2 GTEx Esophagus Mucosa CCDC126 0.12 0.03 lasso 7 0.01 4.3e-02 -5.7 5.9 4.3e-09 -0.79 0.01 0.96 FALSE
3 YFS Blood CCDC126 0.05 0.04 enet 10 0.05 1.6e-15 -6.2 -5.7 1.6e-08 0.51 1.00 0.00 FALSE
4 The Cancer Genome Atlas Esophageal Carcinoma TRA2A 0.18 0.02 blup 40 0.05 1.2e-02 -6.9 -5.7 1.4e-08 0.74 0.01 0.48 TRUE