TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr7:149,847,287-151,252,618
Best TWAS P=6.9e-08 · Best GWAS P=8.84e-10 conditioned to 0.000596
149.8M
150M
150.2M
150.4M
150.6M
150.8M
151M
151.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Testicular Germ Cell Tumors
TMEM176A
0.15
0.00
lasso
10
0.02
5.7e-02
5.5
5.4
6.9e-08
0.66
0.01
0.32
TRUE
1
METSIM
Adipose
AOC1
0.17
0.08
enet
26
0.11
3.2e-16
4.9
5.3
8.8e-08
0.64
0.35
0.64
FALSE