Best TWAS P=6.9e-08 · Best GWAS P=8.84e-10 conditioned to 0.000596
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | AOC1 | 0.17 | 0.08 | enet | 26 | 0.11 | 3.2e-16 | 4.9 | 5.3 | 8.8e-08 | 0.64 | 0.35 | 0.64 | FALSE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TMEM176A | 0.15 | 0.00 | lasso | 10 | 0.02 | 5.7e-02 | 5.5 | 5.4 | 6.9e-08 | 0.66 | 0.01 | 0.32 | TRUE |