TWAS hub - TMEM176A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0250	1.1e-03	0.036	0.025	0.020	0.028	0.032	2.8e-05	4.5e-04	1.3e-03	2.3e-04	7.0e-05
2	GTEx	Cells Transformed fibroblasts	0.1750	0.0600	2.4e-03	0.122	NA	0.112	NA	0.120	2.0e-09	NA	9.7e-09	NA	2.8e-09
3	GTEx	Colon Transverse	0.1620	0.0590	1.5e-03	0.140	NA	0.074	NA	0.112	3.4e-07	NA	2.1e-04	NA	5.5e-06
4	GTEx	Heart Atrial Appendage	0.2040	0.0730	2.0e-03	0.147	NA	0.152	NA	0.180	4.1e-07	NA	2.4e-07	NA	1.7e-08
5	GTEx	Heart Left Ventricle	0.1569	0.0585	4.4e-03	0.097	NA	0.161	NA	0.148	7.5e-06	NA	6.4e-09	NA	2.7e-08
6	GTEx	Skin Sun Exposed Lower leg	0.2660	0.0610	2.7e-05	0.047	NA	0.116	NA	0.122	9.5e-05	NA	8.5e-10	NA	3.0e-10
7	GTEx	Thyroid	0.1230	0.0530	5.4e-03	0.130	NA	0.122	NA	0.132	3.7e-10	NA	1.5e-09	NA	2.7e-10
8	GTEx	Whole Blood	0.2980	0.0590	9.3e-07	0.221	NA	0.207	NA	0.221	4.1e-20	NA	7.7e-19	NA	3.8e-20
9	METSIM	Adipose	0.1854	0.0383	9.8e-13	0.141	0.117	0.146	0.146	0.145	1.6e-20	4.3e-17	3.7e-21	2.9e-21	5.4e-21
10	NTR	Blood	0.5571	0.0298	0.0e+00	0.535	0.520	0.554	0.552	0.550	3.7e-209	3.7e-200	5.2e-220	1.0e-218	1.3e-217
11	ROSMAP	Brain Pre-frontal Cortex	0.2455	0.0412	2.2e-14	0.169	0.147	0.203	0.191	0.200	3.6e-21	2.0e-18	1.5e-25	5.2e-24	4.3e-25
12	YFS	Blood	0.7773	0.0139	0.0e+00	0.749	0.780	0.805	0.803	0.800	0.0e+00	0.0e+00	0.0e+00	0.0e+00	0.0e+00
13	TCGA	Bladder Urothelial Carcinoma	0.0580	0.0310	3.1e-03	0.013	0.031	0.029	NA	0.014	2.5e-02	1.0e-03	1.5e-03	NA	2.0e-02
14	TCGA	Breast Invasive Carcinoma	0.0418	0.0176	2.8e-06	0.006	0.037	0.025	NA	0.021	1.6e-02	4.0e-08	5.4e-06	NA	3.2e-05
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.2152	0.0577	1.6e-13	0.014	0.140	0.135	NA	0.118	9.9e-03	1.7e-15	6.8e-15	NA	3.6e-13
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.1877	0.0544	1.2e-11	0.051	0.114	0.115	NA	0.129	1.8e-06	9.4e-13	6.5e-13	NA	2.6e-14
17	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1730	0.0660	6.3e-06	0.053	0.074	0.037	NA	0.066	5.1e-04	5.1e-05	3.2e-03	NA	1.3e-04
18	TCGA	Lung Adenocarcinoma	0.0914	0.0374	2.0e-05	0.010	0.048	0.023	NA	0.020	1.9e-02	2.6e-06	9.3e-04	NA	1.6e-03
19	TCGA	Lung Squamous Cell Carcinoma	0.0907	0.0338	7.7e-06	0.059	0.060	0.059	NA	0.056	3.1e-07	2.5e-07	2.9e-07	NA	6.0e-07
20	TCGA	Prostate Adenocarcinoma	0.1517	0.0722	7.5e-05	0.011	0.039	0.023	NA	0.026	2.4e-02	6.1e-05	1.8e-03	NA	8.4e-04
21	TCGA	Rectum Adenocarcinoma	0.3550	0.1430	2.2e-03	0.091	0.064	0.062	NA	0.101	3.8e-03	1.3e-02	1.5e-02	NA	2.3e-03
22	TCGA	Stomach Adenocarcinoma	0.1270	0.0580	4.5e-03	0.046	0.035	0.014	NA	0.031	2.8e-04	1.3e-03	3.0e-02	NA	2.4e-03
23	TCGA	Testicular Germ Cell Tumors	0.1540	0.0760	4.1e-03	-0.003	-0.003	-0.002	NA	0.022	4.4e-01	4.3e-01	4.0e-01	NA	5.7e-02
24	TCGA	Thyroid Carcinoma	0.3190	0.0750	1.1e-10	0.089	0.111	0.101	NA	0.091	5.0e-09	6.8e-11	4.5e-10	NA	3.4e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Trunk fat-free mass	4.5	25.6	79.2	7.8	0.2	-2.4	-3.0	-5.4	0.5	-1.6	1.0	2.7	1.7	7.7	1.6	7.5	5.4	5.0	8.5	6.2	-3.9	3.6	7.2	3.0	3.1	8.9	6.0
Trunk predicted mass	4.4	25.3	78.0	7.7	0.2	-2.4	-2.9	-5.3	0.5	-1.5	1.1	2.7	1.7	7.6	1.6	7.5	5.4	5.0	8.5	6.1	-3.9	3.6	7.2	3.0	3.1	8.8	6.0
Whole body water mass	4.0	22.6	68.9	7.3	0.3	-2.5	-3.2	-5.2	0.3	-1.9	1.1	2.6	1.7	7.2	1.6	7.1	5.3	4.6	7.8	5.5	-3.6	3.3	6.7	2.6	3.0	8.3	5.7
Sitting height	3.9	27.5	77.6	7.8	1.1	-0.8	-2.1	-4.0	1.5	-0.7	1.6	2.2	2.4	8.0	2.1	8.5	6.8	6.2	8.4	6.4	-2.3	4.5	5.8	3.9	5.5	8.8	6.5
Whole body fat-free mass	3.8	21.9	67.4	7.2	0.3	-2.5	-3.1	-5.1	0.2	-1.8	1.0	2.6	1.7	7.2	1.6	6.9	5.2	4.6	7.7	5.4	-3.6	3.3	6.6	2.6	2.9	8.2	5.6
Arm fat-free mass (right)	3.6	18.6	52.3	6.4	0.5	-2.1	-2.9	-4.5	0.6	-1.6	1.0	2.3	1.7	6.5	1.5	6.6	4.8	4.3	7.2	5.2	-3.2	3.2	5.8	2.5	3.1	7.2	5.2
Arm predicted mass (right)	3.5	18.1	51.3	6.4	0.3	-1.9	-2.7	-4.4	0.6	-1.4	0.9	2.2	1.6	6.5	1.4	6.5	4.9	4.2	6.9	5.0	-2.9	3.1	5.8	2.6	3.3	7.2	5.3
Height	3.4	64.6	174.2	11.2	3.0	-0.3	-0.8	-4.7	4.0	0.5	3.7	4.8	4.7	11.5	4.6	12.6	9.8	10.3	13.1	10.8	-2.6	7.8	8.9	6.5	7.6	13.2	9.6
Arm predicted mass (left)	3.4	17.2	51.4	6.2	-0.1	-2.2	-2.9	-4.6	0.1	-1.6	0.6	2.0	1.2	6.2	1.1	6.4	4.2	3.9	7.2	5.3	-3.6	2.8	5.7	2.2	2.8	7.0	4.9
Hand grip strength (left)	3.3	8.8	30.6	4.5	0.1	-0.6	-0.9	-2.0	0.4	-0.0	-0.0	0.8	0.3	4.5	0.3	4.2	2.8	3.0	5.3	4.1	-2.2	2.1	4.9	2.1	2.4	5.5	3.6
Impedance of leg (right)	3.3	16.1	57.3	-6.5	-0.3	2.2	2.3	3.2	-0.3	1.7	-1.0	-2.8	-1.5	-6.7	-1.5	-5.4	-4.8	-4.4	-6.1	-4.0	2.0	-3.8	-5.5	-2.1	-2.6	-7.6	-4.4
Impedance of leg (left)	3.3	16.0	56.8	-6.6	-0.6	2.3	2.4	3.5	-0.4	1.6	-1.3	-3.1	-1.7	-6.5	-1.8	-5.2	-4.8	-4.1	-5.9	-3.8	2.2	-3.5	-5.9	-2.3	-1.7	-7.5	-4.5
Medication: Aspirin	3.3	4.3	11.6	0.3	3.4	-2.2	-2.5	-1.0	1.5	-2.0	3.4	3.3	3.4	1.0	3.4	1.1	2.8	2.4	0.7	-0.5	-0.0	1.3	1.0	-1.0	0.7	1.8	2.2
Arm fat-free mass (left)	3.3	16.9	51.3	6.0	0.1	-2.4	-3.0	-4.8	0.1	-1.8	0.8	2.0	1.3	6.0	1.2	6.4	4.1	3.9	7.2	5.2	-3.6	2.6	5.6	2.0	2.7	6.9	4.8
Impedance of whole body	3.3	16.8	56.3	-6.4	-0.4	2.7	2.9	3.8	-0.5	1.8	-1.2	-2.8	-1.5	-6.4	-1.7	-5.7	-4.5	-4.0	-6.5	-4.3	3.1	-3.2	-6.1	-2.1	-1.8	-7.5	-4.7
Medication: Aspirin	3.2	4.2	11.4	0.5	3.4	-1.8	-2.1	-0.9	1.6	-1.6	3.3	3.2	3.3	1.1	3.4	1.2	2.9	2.4	0.7	-0.7	0.4	1.3	1.2	-0.7	0.9	1.8	2.5
Leg fat-free mass (right)	3.1	16.6	53.1	6.3	0.1	-2.4	-3.0	-4.4	-0.3	-2.0	0.7	2.3	1.3	6.4	1.2	5.8	4.7	4.1	6.5	4.4	-3.0	3.1	5.6	2.0	2.7	7.3	4.8
Basal metabolic rate	3.1	17.2	51.6	6.3	-0.0	-2.5	-3.1	-4.8	-0.2	-1.9	0.6	2.1	1.3	6.3	1.1	6.2	4.4	3.9	6.9	4.8	-3.5	2.7	5.8	2.1	2.5	7.2	5.0
Leg predicted mass (right)	3.0	16.2	51.7	6.3	0.1	-2.3	-2.9	-4.3	-0.3	-2.0	0.6	2.2	1.2	6.4	1.1	5.7	4.6	4.0	6.4	4.4	-3.0	3.0	5.6	2.1	2.6	7.2	4.7
Impedance of arm (right)	2.9	13.3	40.1	-5.7	-0.4	1.8	2.3	2.9	-1.1	1.0	-1.0	-2.3	-1.4	-5.8	-1.5	-5.4	-4.2	-3.6	-5.7	-4.0	2.6	-2.8	-5.4	-2.3	-2.1	-6.3	-4.5
Alcohol drinker status: Never	2.9	3.5	9.2	-0.6	2.5	-2.6	-2.5	-2.4	-0.7	-2.0	2.5	2.4	2.3	-1.5	2.2	0.1	-0.4	-1.0	-0.9	-2.4	-1.6	-2.6	0.3	-1.7	-3.0	-0.3	-0.4
Impedance of arm (left)	2.8	13.1	39.5	-5.5	0.3	2.2	2.5	3.3	-0.7	1.3	-0.6	-2.0	-0.8	-5.6	-1.0	-5.4	-3.5	-3.3	-6.3	-4.4	3.1	-2.5	-5.5	-1.9	-1.9	-6.2	-4.2
Illnesses of siblings: Diabetes	2.8	3.4	9.2	1.8	0.2	1.5	1.1	1.1	1.5	1.1	0.1	0.3	-0.1	2.6	0.2	1.9	1.4	2.8	2.8	2.5	0.9	3.0	1.9	1.9	2.8	2.5	2.3
Leg fat-free mass (left)	2.7	14.3	44.9	5.7	0.3	-2.4	-3.0	-4.3	-0.3	-1.9	0.8	2.2	1.4	5.8	1.3	5.3	4.3	3.6	6.0	4.0	-3.0	2.7	5.4	1.9	2.1	6.7	4.6
Qualifications: CSEs or equivalent	2.7	3.6	11.4	-1.5	-1.6	0.1	-0.4	0.6	-1.7	-0.2	-1.6	-1.9	-1.6	-1.9	-1.6	-2.0	-2.0	-3.4	-2.5	-3.0	0.4	-2.7	-0.9	-0.8	-2.5	-3.3	-1.9
Leg predicted mass (left)	2.6	14.0	43.6	5.7	0.3	-2.5	-3.0	-4.3	-0.3	-2.0	0.7	2.2	1.4	5.7	1.2	5.2	4.2	3.5	5.9	3.9	-3.0	2.6	5.4	1.8	2.0	6.6	4.5
Forced expiratory volume in 1-second (FEV1)	2.6	8.9	29.1	3.3	0.5	-0.0	-0.4	-2.0	1.1	0.3	0.8	1.3	1.1	4.1	1.0	3.0	3.5	4.2	4.8	4.8	-2.0	3.6	4.2	2.3	2.5	5.4	4.1
Medication: Allopurinol	2.6	3.5	8.4	1.5	1.1	1.6	1.3	1.3	1.7	1.4	1.2	1.2	1.2	2.3	1.4	1.5	2.7	2.6	1.3	1.5	1.7	2.9	1.6	2.0	2.7	1.9	2.9
Forced vital capacity (FVC)	2.5	9.7	31.1	3.6	0.7	-0.6	-0.9	-2.8	0.9	-0.2	1.3	1.7	1.6	4.2	1.5	3.5	3.6	4.3	5.2	4.6	-2.2	3.3	4.3	2.2	2.4	5.6	4.0
Deep venous thrombosis (DVT) (self-reported)	2.5	3.3	9.3	1.6	1.2	1.3	1.1	1.2	2.3	1.2	1.6	2.0	1.9	2.1	2.2	0.9	3.0	1.5	-0.7	-0.9	2.6	1.8	2.2	2.1	1.1	1.2	2.9
Blood clot in the leg (DVT)	2.4	3.1	9.5	1.7	1.3	0.9	0.6	0.8	2.1	0.8	1.7	2.0	2.0	2.2	2.2	1.0	3.1	1.1	-0.9	-1.3	2.5	1.4	2.4	1.9	0.9	1.2	2.9
Medication for cholesterol	2.4	3.6	12.1	-2.1	0.9	-0.3	-0.1	-1.4	-0.8	-0.4	1.1	0.6	1.1	-3.5	0.8	-2.3	-1.3	-1.3	-2.9	-2.7	-0.8	-2.7	-2.4	-1.8	-3.3	-2.6	-1.9
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	9.7	1.9	0.5	1.2	0.9	-0.1	1.9	0.9	0.1	0.5	0.1	2.4	0.1	1.9	2.1	0.4	0.4	-0.2	2.6	1.4	2.3	1.5	2.9	0.3	3.1
Stomach or abdominal pain in last month	2.2	2.7	10.0	-0.9	-0.9	-1.3	-2.1	-2.1	-2.3	-1.5	-0.7	-1.1	-0.5	-1.7	-0.9	-0.2	-0.9	-2.5	-1.1	-1.6	-1.8	-3.2	-2.0	-1.6	-1.3	-2.2	-1.8
Hand grip strength (right)	2.1	5.7	23.4	3.7	-0.3	-1.3	-1.5	-2.2	-0.7	-0.8	-0.3	0.6	0.0	3.7	0.1	2.9	2.3	2.2	3.6	2.6	-2.3	1.3	4.2	1.3	2.0	4.8	2.9
Serious illness, injury or assault to yourself	2.1	2.5	5.8	1.1	1.2	0.9	0.5	0.5	2.1	0.8	1.4	1.6	1.5	1.9	1.6	1.3	2.4	2.3	0.9	1.2	1.1	2.4	1.3	1.5	1.9	1.9	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.6	19.2	2.3	0.6	0.0	-0.4	-1.5	1.0	0.3	0.9	1.5	1.1	3.3	1.0	2.2	2.9	3.9	4.2	4.3	-1.8	3.3	3.5	1.9	2.3	4.4	3.6
Blood Red Count	2.0	19.0	51.6	3.4	4.6	1.9	1.4	-0.1	4.8	2.2	4.2	6.1	4.7	4.4	4.7	1.8	7.2	6.9	2.5	2.8	0.9	6.0	4.4	3.1	3.2	5.8	6.8
Standing height	2.0	20.2	57.3	6.8	1.1	-0.8	-1.4	-4.5	1.1	-0.4	1.5	2.5	2.2	6.7	2.0	6.8	5.8	5.2	7.0	5.4	-2.4	3.6	5.5	3.3	3.9	7.6	5.7
Medication: Amlodipine	2.0	2.7	9.9	1.2	0.9	-0.5	-0.8	-0.5	1.7	-0.2	0.8	0.9	0.8	1.9	1.0	1.5	2.6	3.1	2.2	2.4	-0.9	2.7	0.1	0.7	2.3	2.5	1.8
Forced vital capacity (FVC), Best measure	2.0	7.1	22.1	2.7	0.7	-0.6	-0.8	-2.2	0.6	-0.4	1.2	1.8	1.4	3.6	1.3	2.4	3.2	4.1	4.3	3.8	-1.7	3.2	3.8	1.5	2.4	4.7	3.6
Comparative height size at age 10	2.0	11.2	27.5	4.0	2.4	-2.0	-2.4	-4.7	0.8	-1.6	3.0	3.7	3.2	4.0	3.2	3.9	5.1	4.1	3.9	2.2	-2.0	2.3	3.8	1.0	1.7	5.2	4.5
Diabetes diagnosed by doctor	2.0	3.3	12.8	2.8	0.7	-0.7	-1.8	-1.1	-0.0	-1.0	0.7	0.7	0.8	2.9	0.8	3.0	2.5	1.5	2.5	1.9	-1.5	1.4	1.4	1.0	1.8	3.6	1.8
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	5.6	2.1	1.2	1.3	0.6	-0.1	0.9	1.0	0.9	1.2	0.9	2.2	1.2	1.0	2.1	1.5	0.2	0.1	1.0	1.5	2.2	2.0	1.2	2.1	2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.6	11.9	0.5	-2.5	1.3	0.7	0.7	-0.4	1.1	-2.2	-1.7	-1.9	-0.5	-1.9	0.2	-0.9	-3.4	-1.1	-1.0	-0.5	-2.3	0.1	0.8	-2.3	-2.9	-0.7
Number of incorrect matches in round	1.9	3.1	9.8	2.0	-1.6	2.3	1.7	2.1	0.9	1.7	-1.5	-1.7	-1.5	2.5	-1.5	2.2	0.0	0.2	2.1	3.1	0.4	1.6	1.6	2.7	1.4	1.1	0.7
Medication: Simvastatin	1.9	2.8	7.6	2.0	0.4	0.8	0.1	1.4	1.7	0.7	0.3	0.2	0.5	2.5	0.6	2.3	2.0	1.9	2.6	2.8	-0.2	2.5	1.0	1.7	2.2	2.5	1.6
Hypothyroidism/myxoedema (self-reported)	1.9	3.7	8.9	-1.8	-1.5	-1.6	-1.8	-1.4	-1.6	-1.5	-1.1	-1.6	-1.3	-2.5	-1.6	-0.6	-3.0	-2.8	0.0	-0.8	-1.7	-2.9	-2.0	-2.2	-1.7	-2.7	-2.9
Commuting to job workplace: Walk	1.9	2.0	7.1	-0.4	-1.9	1.5	1.6	1.6	0.4	1.5	-2.0	-2.1	-2.2	0.0	-2.1	-0.1	-2.7	-1.7	-0.0	0.3	1.8	-0.5	0.7	1.1	1.1	-1.0	-0.6
Hypothyroidism (self reported)	1.8	4.2	12.5	-1.4	-2.2	-1.3	-2.1	-1.4	-1.8	-1.5	-1.7	-2.1	-1.8	-2.1	-2.1	-0.2	-3.1	-3.5	-0.0	-0.9	-1.8	-3.5	-1.6	-1.8	-1.5	-2.8	-2.7
Systolic blood pressure, automated reading	1.8	5.2	20.1	-2.8	1.8	-4.5	-3.2	-2.5	-0.5	-3.7	2.0	1.7	1.7	-2.1	1.6	-2.1	-1.1	2.0	0.9	-0.2	-1.9	0.8	-2.6	-4.4	0.0	0.9	-1.9
Diabetes (mother)	1.8	2.3	6.6	2.6	0.8	1.0	0.7	1.0	1.6	0.9	1.1	0.7	0.9	2.3	0.9	2.2	1.1	1.3	1.9	1.0	1.2	1.4	2.5	2.1	0.8	2.1	1.6
Townsend deprivation index at recruitment	1.8	2.5	5.4	-1.7	-2.2	0.4	-0.2	-0.3	-2.2	0.1	-2.2	-2.3	-2.2	-1.6	-2.2	-1.7	-2.0	-2.0	-1.2	-0.6	-1.2	-1.9	-1.1	-0.7	-0.8	-2.0	-1.5
High blood pressure (mother)	1.8	2.5	9.3	1.8	-1.1	-1.8	-2.5	-0.9	-0.5	-1.6	-1.0	-0.9	-1.0	2.2	-0.9	1.8	0.8	0.4	3.0	2.0	-2.4	1.0	1.6	-0.0	0.8	2.3	1.0
Pain all over the body in last month	1.8	1.9	5.2	-0.2	-0.2	1.8	2.3	1.6	1.8	2.3	-0.1	0.6	-0.0	0.7	0.3	-1.3	0.6	1.7	-0.1	0.2	2.0	1.9	2.1	1.7	0.9	0.6	2.1
Diabetes (self-reported)	1.8	2.7	9.4	2.9	-0.1	-0.5	-1.6	-1.2	-0.2	-0.8	0.2	0.3	0.5	2.8	0.3	3.1	2.4	0.7	2.4	2.1	-1.8	0.9	1.1	1.0	1.4	2.8	1.4
Chronic bronchitis/emphysema (mother)	1.8	2.1	6.8	-1.5	1.9	0.2	-0.4	-1.3	0.4	0.2	1.4	1.1	1.7	-2.3	1.7	-1.7	1.0	0.2	-2.6	-2.4	-0.1	-1.2	-2.4	-0.7	-0.9	-2.0	-0.1
Worry too long after embarrassment	1.8	2.9	7.6	2.5	1.5	1.2	0.7	0.8	1.1	0.9	1.9	1.9	2.1	2.2	2.0	2.4	2.8	1.2	0.9	0.4	1.0	1.0	2.3	2.1	0.3	1.9	2.4
Osteoarthritis (self-reported)	1.8	2.4	8.8	-2.7	-0.1	1.9	1.6	0.2	-0.0	1.5	-0.9	-1.0	-0.7	-2.6	-0.8	-2.1	-1.5	-1.0	-2.2	-1.5	1.6	-1.3	-1.8	0.0	-0.1	-3.0	-0.7
Basal cell carcinoma (self-reported)	1.8	2.1	9.4	-0.9	-0.3	-1.5	-2.2	-2.3	-1.7	-1.8	-0.1	-0.1	-0.1	-1.3	-0.5	-0.6	-1.5	-1.1	0.0	0.0	-3.1	-1.7	-1.3	-1.4	-2.4	-0.2	-2.1
Lung FVC	1.7	8.4	27.0	3.0	1.7	-0.6	-0.8	-1.5	1.5	-0.4	2.1	2.4	2.1	3.9	2.0	3.7	2.9	4.3	4.9	3.9	-0.9	3.3	3.6	1.5	2.6	5.2	3.3
Supplements: Zinc	1.7	1.8	6.3	1.8	-0.0	0.5	0.2	0.2	0.7	0.3	-0.0	0.2	0.0	2.5	-0.0	1.4	1.5	1.6	1.5	1.4	0.8	2.1	1.9	1.3	2.5	1.6	1.8
Had other major operations	1.7	2.1	5.9	2.1	0.3	1.4	1.0	0.5	1.6	1.5	0.3	0.7	0.7	1.8	0.8	2.1	2.0	1.0	1.9	2.4	-0.8	1.6	1.2	2.3	-0.1	1.1	1.5
Medication: Blood pressure	1.7	3.3	10.7	1.5	-0.7	-2.4	-2.4	-0.0	-0.1	-1.9	-0.3	-0.2	-0.4	2.8	-0.2	1.9	1.5	1.6	3.3	2.6	-1.5	2.4	1.6	-0.2	2.2	3.0	1.3
Peak expiratory flow (PEF)	1.6	3.7	11.6	1.2	0.6	-0.2	-0.5	-1.6	0.9	-0.0	1.1	1.3	1.1	2.1	1.0	1.4	2.3	2.8	3.0	3.1	-1.4	2.4	3.0	1.0	1.5	3.4	3.1
Miserableness	1.6	2.8	12.4	0.3	-1.5	3.5	2.8	3.5	1.2	2.9	-1.5	-1.7	-1.5	0.6	-1.3	0.2	-0.5	-0.3	-0.2	0.9	1.8	0.7	0.2	2.6	1.2	-0.4	0.1
Medication: Lisinopril	1.6	2.1	4.7	2.1	1.3	-0.5	-0.9	-0.5	1.3	-0.3	1.4	1.7	1.6	2.1	1.6	1.9	2.2	1.6	1.8	1.3	-0.6	1.7	1.2	0.8	0.0	2.1	1.1
Reaction Time	1.5	2.9	7.8	-1.9	1.2	-1.7	-1.8	0.0	-1.5	-2.0	0.7	0.2	0.6	-2.0	0.4	-2.3	-0.5	-1.1	-2.7	-2.7	-0.8	-1.3	-2.8	-2.3	-1.7	-1.3	-2.4
HDL Cholesterol	1.5	2.5	14.0	-0.3	1.1	1.9	2.4	2.4	2.3	2.3	1.4	0.6	1.3	-0.5	1.5	-0.4	0.5	-0.2	-1.7	-1.9	3.7	0.1	0.3	1.5	0.0	-1.5	0.8
Knee pain experienced in last month	1.5	2.4	10.8	-1.5	-0.1	1.1	0.3	0.1	-0.3	0.7	-0.0	-0.5	0.2	-1.9	-0.0	-1.1	0.2	-2.1	-3.2	-3.3	2.1	-2.3	-1.3	0.1	-0.3	-3.3	0.0
Illnesses of father: High blood pressure	1.5	1.8	7.6	-0.9	0.5	-2.8	-2.4	-2.4	-1.3	-2.2	0.5	0.6	0.6	-0.7	0.4	-1.4	0.2	0.5	-0.3	-0.5	-2.2	-0.2	-1.0	-2.1	-0.5	0.9	-1.1
Alcohol drinker status: Previous	1.5	1.7	6.9	0.2	-0.4	2.6	2.5	1.8	1.3	2.4	-0.7	-0.7	-0.8	0.6	-0.5	-0.1	-0.4	0.9	0.6	1.8	1.1	1.4	1.4	2.1	0.4	0.4	0.5
Type 2 Diabetes (T2D) (2018)	1.4	2.7	9.7	2.9	0.4	-1.1	-1.6	-0.9	-0.4	-1.0	0.3	0.4	0.6	2.6	0.4	3.1	2.4	0.9	2.3	2.2	-2.1	0.9	0.7	0.7	1.0	2.9	1.1
High blood pressure	1.4	3.9	12.3	1.0	0.2	-3.4	-3.4	-1.4	0.0	-2.7	0.4	0.2	0.3	1.9	0.5	1.3	1.5	2.2	3.5	2.6	-2.9	2.2	0.8	-1.4	1.4	3.0	0.7
Medication: Levothyroxine sodium	1.4	2.3	5.8	-1.6	-0.7	-1.4	-1.6	-1.6	-0.9	-1.1	-0.7	-0.9	-0.7	-2.1	-1.0	0.0	-2.4	-2.1	0.5	0.1	-2.1	-2.3	-1.7	-1.8	-1.4	-1.9	-2.0
Illnesses of siblings	1.4	2.0	8.4	-1.3	0.9	0.2	0.9	0.7	0.4	0.3	0.8	0.5	0.7	-1.8	0.7	-1.6	-0.3	-1.2	-2.9	-2.8	1.9	-0.9	-1.9	-0.6	-1.6	-2.4	-1.4
Mouth/teeth dental problems: Loose teeth	1.4	1.7	5.4	-1.3	-1.0	0.7	-0.4	-0.2	-0.5	0.2	-1.0	-1.1	-0.9	-1.6	-0.9	-1.5	-1.5	-2.2	-1.4	-1.2	-0.4	-1.7	-1.0	-0.4	-2.1	-2.3	-1.6
Emphysema/chronic bronchitis	1.4	1.6	7.3	-0.1	1.2	-0.0	0.1	0.0	1.6	0.1	1.5	1.4	1.4	0.8	1.5	0.1	1.9	2.7	0.6	1.0	0.8	2.3	0.1	0.2	2.1	1.0	1.4
Medication: Seretide 50 evohaler	1.4	1.6	4.8	-0.9	-1.0	-0.4	-0.5	-0.4	-1.8	-0.8	-0.7	-0.8	-0.7	-1.3	-0.7	-1.1	-0.8	-2.0	-2.2	-2.0	-0.1	-2.2	-0.7	-1.2	-1.0	-2.1	-1.0
Number of full sisters	1.4	1.7	5.3	0.9	1.3	0.4	-0.0	0.9	1.4	0.4	0.9	1.2	0.8	1.5	1.2	0.8	0.7	2.0	1.8	1.4	-0.0	2.0	2.0	1.3	0.5	2.3	1.6
Eye problems/disorders: Cataract	1.4	1.6	7.3	1.4	-0.3	0.3	-0.3	-0.7	0.8	0.2	0.1	0.8	0.2	2.2	0.3	0.6	1.7	1.3	1.3	1.2	-0.6	1.8	2.7	1.3	0.3	2.3	2.0
Breast Cancer	1.3	3.1	13.8	-0.1	0.6	-1.9	-1.9	-2.2	-0.5	-1.8	0.8	1.1	0.6	0.9	0.4	0.6	0.5	2.8	3.7	2.8	-2.6	2.1	1.0	-1.1	0.6	3.2	0.9
Bipolar Disorder (2011)	1.3	1.2	4.0	-1.2	-0.8	-1.3	-0.9	-1.6	-1.5	0.0	0.0	-0.7	-1.0	-0.9	-1.0	-1.0	-1.7	-0.6	0.2	0.3	-2.0	-0.8	-0.8	-1.6	-1.1	0.1	-1.9
Allergy or Eczema	1.3	3.3	8.1	-0.5	-2.8	2.8	2.3	0.6	-1.1	2.4	-2.7	-2.3	-2.5	-1.1	-2.4	-1.7	-0.7	-2.3	-2.2	-1.0	0.6	-1.9	-0.0	1.3	-0.6	-2.2	-0.6
Medication: Ramipril	1.3	1.7	5.1	1.1	0.9	1.1	0.4	1.6	1.5	1.1	0.8	0.7	0.8	1.3	1.2	0.8	2.3	2.1	0.6	1.4	-0.2	1.8	0.4	1.6	1.4	1.5	2.0
Medication: Lansoprazole	1.3	1.5	4.5	-1.1	2.1	-1.7	-1.9	-1.7	-0.3	-1.8	1.9	1.6	1.7	-0.9	1.5	0.5	-0.0	0.6	0.4	0.2	-1.2	-0.2	-1.1	-1.5	-0.2	0.4	-0.2
Leg fat percentage (right)	1.3	4.7	16.4	-3.9	-1.0	-1.2	-1.3	-0.1	-1.2	-1.3	-0.8	-1.1	-0.8	-3.6	-1.1	-2.4	-3.2	-2.7	-1.9	-2.1	-0.0	-2.4	-2.6	-2.6	-1.5	-4.0	-1.9
Hypertension (Self-reported)	1.3	3.6	12.0	1.0	0.1	-3.1	-3.3	-0.9	0.3	-2.6	0.4	0.1	0.3	2.0	0.5	1.5	1.5	2.2	3.5	2.6	-2.4	2.4	0.7	-1.1	1.7	2.8	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	4.0	0.2	-2.0	1.7	1.3	0.9	-0.1	1.4	-2.0	-1.5	-1.8	0.2	-1.6	-0.5	-0.3	-1.3	-1.1	-0.8	1.3	-0.6	0.8	1.2	0.5	-1.4	0.1
Financial situation satisfaction	1.3	1.6	3.6	0.7	1.3	1.3	1.2	1.1	1.8	1.5	1.1	1.1	1.3	0.8	1.5	0.9	1.7	1.9	0.4	0.3	1.6	1.2	1.0	1.4	1.6	0.7	1.7
High cholesterol (Self-reported)	1.3	2.3	11.6	0.8	-0.0	0.8	0.6	1.3	1.3	0.7	0.0	-0.3	0.2	1.9	0.3	0.5	2.1	2.4	1.6	1.6	1.5	3.0	0.7	1.1	3.4	2.1	1.7
Vascular/heart problems diagnosed by doctor	1.3	3.5	10.2	-1.0	-0.7	3.1	3.2	0.9	-0.5	2.4	-0.8	-0.8	-0.8	-2.0	-1.0	-1.3	-1.9	-2.4	-3.0	-2.2	2.4	-2.3	-1.0	1.1	-1.6	-2.9	-1.1
Cardiovascular Disease	1.2	4.1	10.9	1.0	-1.0	-3.0	-3.0	-0.2	-0.3	-2.4	-0.9	-0.8	-0.8	2.5	-0.5	1.4	2.0	2.2	3.3	2.8	-2.1	2.8	0.4	-0.8	3.3	2.7	1.4
Relative age voice broke	1.2	1.8	7.6	0.4	-0.7	2.8	1.9	1.0	0.2	2.4	-1.1	-1.5	-0.8	-0.8	-0.8	0.4	-0.0	-1.9	-1.2	-0.9	1.1	-2.4	-0.1	1.7	0.1	-1.6	-0.2
Hayfever, allergic rhinitis or eczema	1.2	2.7	5.8	-1.1	-2.3	2.3	1.9	0.7	-1.0	1.8	-2.4	-1.9	-2.3	-1.3	-2.3	-2.3	-1.4	-1.8	-2.0	-0.9	0.6	-1.1	-0.5	0.7	-0.6	-2.0	-0.8
Asthma	1.2	2.4	7.5	-0.7	-2.7	1.9	1.5	0.6	-1.0	1.4	-2.2	-2.1	-2.1	-1.2	-2.2	-1.3	-2.1	-1.5	-0.8	-0.1	0.1	-1.4	-0.7	0.4	-0.9	-2.2	-1.6
Pulse wave reflection index	1.2	1.5	5.0	0.5	2.2	-0.0	-0.3	-0.0	1.0	0.2	2.0	2.0	2.0	0.6	2.2	1.3	1.3	0.6	-0.0	-1.3	1.8	0.2	0.9	0.9	0.3	0.8	1.4
Ever highly irritable/argumentative for 2 days	1.2	1.5	3.8	1.2	-0.9	2.0	1.3	1.5	0.2	1.4	-1.1	-0.6	-0.9	1.7	-0.7	0.3	1.5	1.0	0.4	0.7	0.9	1.5	1.3	1.7	1.7	0.7	1.4
High blood pressure (siblings)	1.2	1.7	8.3	1.1	-0.6	-0.7	-1.0	-0.2	-0.6	-0.6	-0.6	-0.6	-0.6	1.5	-0.6	1.7	-0.4	1.0	2.9	2.6	-1.7	0.4	1.7	0.3	1.5	2.6	0.6
Body fat percentage	1.2	4.8	15.1	-3.8	-0.8	-1.1	-1.3	-0.3	-1.7	-1.5	-0.8	-1.2	-0.8	-3.5	-1.2	-2.6	-3.0	-2.6	-2.4	-2.4	0.2	-2.4	-3.0	-2.7	-1.1	-3.9	-2.2
Angina (self-reported)	1.2	1.5	7.8	1.6	1.7	0.8	-0.3	0.3	1.3	0.6	1.0	1.1	1.4	1.5	1.2	1.5	2.8	1.1	0.3	0.4	0.2	1.0	0.7	1.5	0.8	0.9	1.9
Ever taken oral contraceptive pill	1.2	1.3	5.6	0.5	-1.2	2.4	2.0	1.5	0.5	2.0	-1.3	-1.1	-1.0	0.2	-0.9	0.2	-0.1	-1.0	-0.2	-0.2	1.6	-0.1	0.3	1.8	0.3	-1.1	-0.2
Age started oral contraceptive pill	1.2	1.5	4.3	0.7	1.2	0.5	0.2	0.1	1.2	0.2	1.6	1.2	1.5	1.2	1.5	1.2	1.7	1.9	0.5	0.8	0.9	1.6	-0.2	0.9	2.1	1.6	1.1
Diastolic blood pressure, automated reading	1.2	3.7	14.2	-2.9	0.4	-3.7	-2.7	-1.7	-0.8	-2.9	0.6	0.4	0.2	-1.8	0.3	-3.3	-1.8	1.5	0.7	0.2	-2.6	0.9	-1.1	-3.8	-0.7	0.8	-1.1
Unable to work because of sickness or disability	1.2	1.5	4.3	0.0	1.5	1.6	1.0	0.9	1.7	1.4	1.5	1.4	1.6	0.2	1.9	-0.7	1.2	0.6	-1.3	-1.4	2.1	0.7	1.1	1.3	-0.5	-0.2	1.2
Cholesterol lowering medication	1.2	1.8	5.5	1.4	-0.1	0.7	0.4	1.4	0.9	0.7	-0.4	-0.4	-0.6	2.1	-0.3	1.4	0.6	1.2	2.0	2.0	0.5	2.0	1.6	1.4	1.9	2.4	1.3
LDL Cholesterol	1.1	1.8	6.4	-0.7	-1.9	0.1	0.2	-0.2	-1.9	-0.2	-2.2	-2.0	-2.5	-0.3	-2.5	-1.2	-1.9	-1.6	-0.7	0.4	-1.2	-0.9	0.0	-0.4	-0.9	-0.6	-1.4
Ever had hysterectomy (womb removed)	1.1	1.2	3.9	-0.0	0.7	1.7	1.5	1.2	1.9	1.5	0.7	0.9	0.6	0.5	0.7	-0.3	0.6	0.5	-0.7	-0.6	2.0	1.3	1.3	1.2	0.6	-0.5	1.6
Trunk fat percentage	1.1	4.5	13.6	-3.7	-0.7	-0.9	-1.2	-0.4	-1.7	-1.4	-0.8	-1.1	-0.7	-3.4	-1.1	-2.6	-2.7	-2.4	-2.4	-2.4	0.3	-2.2	-3.0	-2.5	-1.0	-3.7	-2.1
Past tobacco smoking	1.1	2.0	5.1	-1.9	1.8	-0.7	-0.6	-0.6	-0.7	-1.2	1.7	1.3	1.5	-2.2	1.2	-2.3	0.0	0.3	-1.6	-1.3	-1.0	-0.6	-1.9	-2.2	-1.8	-1.1	-1.5
Alcohol usually taken with meals	1.1	1.8	5.5	0.6	-2.2	1.0	1.1	1.4	-0.8	0.9	-2.1	-2.0	-2.1	0.0	-2.1	-0.5	-0.9	-2.3	-1.2	-0.4	0.2	-1.0	-0.2	0.7	-0.9	-1.4	-1.2
Weight	1.1	5.3	16.2	3.0	-0.5	-2.1	-2.7	-3.5	-0.8	-1.9	0.1	1.0	0.6	3.1	0.3	3.4	2.0	1.7	4.0	2.5	-2.4	1.1	3.0	0.5	1.4	3.5	2.8
Alcohol intake versus 10 years previously	1.1	1.6	3.6	1.7	-0.8	1.7	1.7	1.0	0.5	1.7	-1.0	-1.1	-1.0	1.6	-0.7	1.1	1.1	0.7	0.7	0.5	1.4	0.7	1.9	1.9	1.7	0.4	1.4
Prospective memory result	1.1	1.3	3.6	0.1	1.5	1.0	0.6	0.7	1.9	0.9	1.2	1.1	1.3	0.7	1.3	0.7	1.0	1.6	0.5	0.3	1.5	1.2	0.9	1.3	1.5	0.9	1.6
Gout (self-reported)	1.1	1.6	4.5	1.0	-0.1	1.9	1.7	1.6	0.8	1.8	-0.4	-0.3	-0.3	1.1	-0.2	1.3	1.4	1.0	1.1	1.4	0.9	1.1	1.1	1.6	2.1	-0.0	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.7	-0.6	-1.1	-0.6	-1.9	-1.5	-1.6	-1.0	-0.8	-1.2	-0.4	-1.0	-0.8	-0.1	0.0	-1.1	-0.3	-0.3	-1.9	-1.7	-1.7	-0.8	-0.2	-1.6	-0.9
Guilty feelings	1.1	1.7	6.1	2.1	-0.4	2.2	1.4	1.0	0.4	1.8	-0.1	0.1	0.2	1.3	0.4	1.4	2.2	-0.4	-0.7	-1.1	1.7	-0.2	1.2	2.5	0.0	0.2	1.6
Leg fat percentage (left)	1.1	4.2	13.9	-3.6	-1.2	-1.2	-1.3	0.1	-1.3	-1.4	-0.9	-1.2	-1.0	-3.2	-1.3	-2.2	-3.2	-2.4	-1.6	-1.8	0.0	-2.1	-2.6	-2.6	-0.9	-3.7	-1.9
Pain experienced in last month	1.1	1.9	10.1	1.1	-1.2	0.1	0.9	1.1	-0.0	0.4	-1.5	-1.4	-1.4	1.6	-1.3	1.2	0.1	1.1	2.5	3.2	-0.7	1.8	0.4	0.8	1.8	1.9	0.1
Alzheimer’s Disease (in mother)	1.0	1.1	5.3	-0.7	0.5	-0.5	-0.4	-0.6	-0.5	-0.3	0.6	0.7	0.9	-1.5	0.7	-1.2	0.0	-1.1	-1.7	-1.7	-1.1	-1.4	-1.5	-0.9	-2.3	-0.8	-0.7
Chronotype (morning person)	1.0	2.3	8.5	0.8	0.9	-2.9	-2.8	-2.1	-0.3	-2.3	1.0	1.4	1.3	0.7	1.1	1.9	1.5	0.8	2.1	0.5	-2.0	0.1	-0.6	-1.3	0.3	1.5	0.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.5	-0.7	1.2	-1.9	-1.6	-1.3	0.1	-1.8	1.6	1.5	1.2	-0.1	1.2	0.3	-0.5	0.9	1.0	-0.0	-0.3	0.3	-0.0	-1.7	0.1	0.3	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	7.2	1.0	-0.5	1.4	0.3	0.7	-0.1	1.1	-0.1	-0.3	0.0	-0.1	0.2	0.3	1.1	-2.7	-2.0	-1.9	-0.3	-2.2	1.1	1.4	-2.5	-1.6	0.6
Financial difficulties in last 2 years	1.0	1.3	5.4	1.7	0.6	0.9	0.7	0.8	1.1	1.3	0.3	0.7	0.5	1.4	1.0	0.7	1.6	0.5	-0.3	-0.7	1.2	0.3	2.3	1.7	0.4	0.8	2.2
Heart attack	1.0	1.3	3.2	0.8	1.6	-0.7	-0.8	-0.6	0.5	-0.5	1.5	1.8	1.5	1.1	1.6	0.7	1.4	1.5	0.3	-0.3	0.3	0.7	1.5	0.0	1.0	1.7	1.7
Arm fat percentage (right)	1.0	4.0	8.4	-2.9	-1.0	-1.8	-1.8	-1.1	-2.3	-2.0	-0.8	-0.8	-0.8	-2.8	-1.2	-2.3	-2.9	-2.5	-1.6	-1.9	-0.8	-2.2	-2.0	-2.8	-1.7	-2.6	-2.0
Number of live births	1.0	1.4	3.7	1.6	0.5	0.8	0.8	0.6	1.6	0.9	0.3	0.9	0.3	1.9	0.6	1.3	1.0	1.4	1.2	1.3	0.8	1.9	1.3	1.5	0.7	1.9	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	9.7	3.1	-0.3	0.2	0.0	-0.2	0.2	0.3	0.2	0.3	0.4	2.5	0.4	2.7	1.2	1.0	2.2	1.8	-0.9	0.6	2.1	2.1	0.2	2.1	1.2
Ever smoked	1.0	1.7	6.0	2.1	-1.4	1.1	0.9	0.5	0.9	1.6	-1.4	-1.0	-1.1	1.9	-0.9	2.1	0.0	-0.5	1.2	1.1	0.7	0.2	1.9	2.4	0.8	0.9	1.1
Number of operations (self-reported)	1.0	1.5	6.3	1.4	0.2	2.1	0.8	-0.7	1.5	1.9	-0.4	0.4	0.4	1.1	0.2	1.9	1.8	-0.4	0.6	0.8	0.1	0.1	1.6	2.5	-0.2	-0.5	2.1
Ovarian Cancer	0.9	1.2	5.3	-2.3	-0.1	-0.7	-0.4	-0.9	-0.2	-0.3	-0.3	0.1	-0.4	-1.9	-0.6	-1.5	-1.6	-1.0	-0.6	-0.2	-1.3	-1.1	-0.7	-1.3	-1.5	-1.6	-0.6
Systolic Blood Pressure	0.9	4.5	23.3	-1.7	0.6	-4.8	-3.4	-2.5	-1.2	-3.9	0.7	0.4	0.5	-0.9	0.5	-1.6	-0.2	2.3	1.5	0.6	-2.7	1.2	-2.2	-4.1	0.9	1.8	-1.1
Frequency of depressed mood in last 2 weeks	0.9	1.2	4.3	0.7	-0.3	2.0	1.5	1.4	0.8	2.1	-0.1	-0.1	0.1	0.0	0.2	0.5	1.1	-1.3	-1.1	-0.7	0.5	-0.9	1.0	1.7	-1.2	-1.7	1.2
Angina	0.9	1.2	6.1	1.3	1.7	0.4	-0.6	-0.1	1.0	0.2	1.0	1.0	1.4	1.3	1.2	1.5	2.5	1.1	0.5	0.5	-0.0	0.9	0.5	1.1	0.8	0.9	1.6
Medication: Metformin	0.9	1.3	6.8	1.7	0.3	-0.5	-0.8	-0.3	0.2	-0.4	0.6	0.7	0.8	2.0	0.8	1.1	1.8	1.1	1.2	1.1	-0.7	1.5	1.2	0.8	0.6	2.6	1.0
Average weekly fortified wine intake	0.9	1.1	4.3	-0.4	-0.2	-0.3	-0.3	1.1	-0.5	-0.5	-0.4	-0.2	-0.4	-0.7	-0.4	-0.9	-0.9	-2.0	-1.4	-2.0	0.6	-1.2	-0.4	-0.6	-2.1	-1.9	-1.3
Waist circumference	0.9	3.3	11.7	1.9	-0.6	-1.4	-1.9	-2.1	-0.1	-1.2	0.0	0.8	0.5	2.4	0.2	2.5	1.6	1.7	3.4	2.6	-1.7	1.6	2.0	0.5	1.8	2.8	2.5
Nervous feelings	0.9	1.7	5.6	1.1	0.3	2.1	1.9	2.4	1.3	1.7	0.2	-0.0	0.4	1.1	0.6	0.0	2.3	0.7	-0.8	-0.5	2.0	1.2	0.4	1.7	1.1	0.1	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	6.2	0.2	-0.6	1.0	0.2	-0.0	-0.7	1.0	-0.3	-0.2	0.2	-0.9	0.2	-0.8	1.2	-2.0	-2.4	-2.3	-0.4	-2.3	-0.2	0.7	-2.0	-2.5	0.2
Pulse wave Arterial Stiffness index	0.9	1.1	2.8	-0.3	1.3	0.1	-0.1	-0.2	0.8	-0.0	1.6	1.7	1.4	0.6	1.6	0.2	0.8	1.3	-0.1	-0.6	1.6	1.0	0.7	0.3	1.4	1.6	1.4
Shortness of breath walking on level ground	0.9	1.0	4.0	-0.4	1.0	-0.1	-0.1	0.3	1.4	-0.1	1.3	1.2	1.4	0.4	1.4	0.5	1.1	2.0	1.1	0.9	0.8	1.8	-0.0	0.0	1.3	0.5	0.9
Arm fat percentage (left)	0.9	3.5	7.8	-2.8	-0.9	-1.5	-1.6	-0.7	-2.0	-1.8	-0.8	-0.8	-0.7	-2.6	-1.1	-2.4	-2.5	-2.3	-1.9	-2.0	-0.3	-1.9	-2.1	-2.5	-1.4	-2.6	-1.9
Ever had bowel cancer screening	0.9	1.0	3.2	-0.0	1.6	-0.9	-1.6	-1.7	0.1	-1.2	1.8	1.7	1.7	-0.1	1.4	1.1	-0.0	-0.1	0.6	-0.3	-0.5	-0.5	-0.3	-0.7	-0.3	0.4	-0.3
Friendships satisfaction	0.9	1.1	4.0	0.6	1.1	0.9	1.1	1.1	0.8	0.9	1.0	1.0	1.3	0.3	1.3	-0.6	2.0	2.0	-0.5	-0.4	1.0	1.2	0.4	0.6	0.9	1.0	0.9
Asthma (self-reported)	0.9	1.8	6.4	-0.4	-2.5	1.7	1.3	0.5	-1.1	1.2	-2.0	-1.9	-1.9	-0.9	-2.0	-0.9	-2.0	-1.2	-0.5	0.2	-0.1	-1.3	-0.4	0.5	-0.8	-1.6	-1.5
Ever depressed for a whole week	0.9	1.1	2.8	0.9	1.3	0.7	-0.4	0.2	0.8	0.2	1.2	1.0	1.4	1.2	1.4	1.1	1.6	1.4	0.2	-0.6	1.3	1.0	0.7	1.3	1.2	0.9	1.7
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.0	0.9	1.2	-0.7	-0.9	-0.8	0.2	-0.6	1.2	1.5	1.2	1.2	1.3	0.7	1.4	1.4	0.4	-0.2	0.2	0.6	1.6	0.0	1.1	1.7	1.7
Depression (Nagel 2018)	0.8	1.1	3.1	1.2	-0.1	1.5	1.1	1.4	1.0	1.5	0.1	0.5	0.2	0.2	0.3	0.9	0.9	-1.7	-1.0	-1.0	0.4	-1.1	0.9	1.3	-1.8	-1.6	0.9
Prostate Cancer	0.8	1.1	3.5	0.2	1.1	0.1	-0.2	-0.6	1.1	-0.4	1.3	1.0	1.1	1.0	0.9	1.5	0.2	1.7	1.6	1.3	0.9	1.9	-0.6	0.3	1.3	1.5	-0.2
Mean Putamen Volume	0.8	0.9	4.0	-0.3	1.5	-0.8	-0.7	-0.7	0.5	-0.8	1.6	2.0	1.5	0.2	1.2	0.1	1.0	1.4	0.4	0.1	0.2	1.0	-0.2	-0.9	1.2	0.9	0.5
Primary Biliary Cirrhosis	0.8	1.1	2.6	1.4	-1.5	0.5	0.8	1.0	-0.6	0.3	-1.5	-1.5	-1.6	1.4	-1.5	1.0	-0.9	-1.4	0.6	1.1	0.0	0.0	0.9	0.9	0.5	0.4	-0.5
Waist Hip Ratio (WHR)	0.8	3.7	8.9	1.5	0.0	1.7	1.3	1.3	2.0	1.9	-0.1	0.1	0.2	2.4	0.4	0.8	2.6	2.7	1.4	2.4	0.5	2.9	2.1	2.4	2.7	2.9	3.0
Respiratory disease	0.8	1.7	4.4	-0.8	-2.0	1.2	0.7	-0.7	-1.7	0.7	-1.4	-1.2	-1.4	-1.4	-1.5	-1.6	-1.5	-1.5	-1.6	-0.9	-0.4	-2.1	-0.3	-0.1	-1.0	-1.8	-1.3
Diabetes (father)	0.8	1.0	3.2	-0.1	1.0	1.0	0.4	0.3	1.6	0.8	1.4	1.8	1.4	0.2	1.6	-0.6	1.1	0.4	-1.3	-1.4	1.0	0.3	1.0	0.9	-0.5	-0.0	1.2
Medication: Atenolol	0.8	1.1	3.0	0.6	0.9	-1.1	-1.6	-0.6	-0.1	-1.1	0.5	0.4	0.5	1.0	0.6	1.1	1.1	1.6	1.7	1.0	-1.1	1.0	0.6	-0.3	1.1	1.5	1.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.4	-1.2	-0.9	0.2	-0.2	-0.5	-1.0	-0.0	-0.8	-1.1	-1.1	-1.2	-1.0	-1.8	-1.7	-1.4	-1.7	-1.0	-0.6	-1.3	-0.5	-0.1	-1.0	-0.3	-1.2
Illnesses of mother	0.8	1.0	3.5	-1.4	-0.5	-0.3	0.1	-0.7	-1.5	-0.5	-0.2	-0.3	-0.1	-1.6	-0.5	-0.6	-1.3	-0.9	-1.0	-0.8	0.2	-1.5	-1.9	-1.0	-0.6	-1.7	-1.3
Hair/balding pattern: Pattern 4	0.8	2.0	7.6	1.5	-1.9	-0.4	-1.2	-1.3	-1.1	-0.4	-1.2	-1.6	-1.1	1.0	-1.3	2.5	-0.0	-0.3	2.4	2.4	-2.8	-0.8	0.7	0.6	-0.0	1.3	0.4
Birth weight of first child	0.8	1.5	5.1	-1.0	-1.0	-0.9	-1.1	-2.3	-2.1	-1.1	-0.9	-0.7	-1.1	-1.2	-1.1	-1.7	-1.2	-1.1	-1.1	-0.9	-1.7	-1.2	-0.5	-1.3	-1.3	-0.2	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	4.9	0.9	-1.8	1.0	0.3	2.2	-0.1	0.4	-1.3	-0.8	-1.3	1.2	-1.0	-0.6	0.2	-1.1	-1.1	-1.3	1.2	0.3	1.3	1.1	-0.1	-0.5	0.2
Medication: Blood pressure	0.8	1.4	6.9	-0.1	1.3	-0.4	-0.9	0.1	1.0	-0.3	1.2	1.0	1.3	0.4	1.4	-0.1	2.0	2.6	0.7	1.1	-1.0	1.7	-0.0	-0.1	1.4	1.9	1.3
Mean time to correctly identify matches	0.8	1.5	5.7	-1.3	1.2	-1.0	-1.0	0.5	-0.3	-1.2	1.1	0.7	1.0	-1.4	0.8	-1.0	-0.3	-0.8	-1.8	-2.3	0.4	-0.9	-2.4	-1.4	-1.0	-1.2	-1.8
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	4.5	-0.5	0.3	-0.7	-0.8	-0.7	-1.2	-1.1	0.3	-0.4	-0.1	-0.9	-0.3	0.2	-1.5	-1.2	-0.1	-0.3	-1.1	-1.5	-1.2	-1.0	-1.2	-0.7	-2.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.8	0.5	0.3	1.7	1.7	1.2	1.7	1.9	0.4	0.2	0.6	0.2	0.6	0.9	0.5	-0.2	-0.0	-0.1	1.8	-0.1	0.8	1.8	-0.2	-0.5	0.6
Medication: Gliclazide	0.8	0.9	4.3	-0.5	0.5	-2.0	-1.7	-1.3	-0.9	-2.1	0.4	-0.1	0.1	0.0	-0.1	0.3	-0.1	0.5	0.9	-0.1	-0.2	0.6	-0.8	-1.8	1.2	0.4	0.1
Hearing aid user	0.8	0.8	4.5	-2.1	-0.5	0.3	0.4	0.3	-0.2	0.1	-0.5	-0.8	-0.7	-1.5	-0.8	-1.5	-1.5	0.6	0.1	0.8	-0.4	0.3	-1.7	-0.9	0.7	-0.9	-0.6
Medication: Bendroflumethiazide	0.8	1.2	6.2	1.5	-0.5	-1.2	-1.0	-0.2	-0.1	-0.9	-0.8	-0.6	-0.9	1.5	-0.8	1.6	0.1	0.0	2.5	1.9	-1.5	0.9	0.8	-0.2	0.0	1.4	-0.0
Coronary Artery Disease (CAD)	0.7	0.8	2.6	0.5	-0.7	1.0	1.1	1.6	1.2	1.1	0.0	0.2	-0.4	0.8	-0.0	-1.2	0.5	0.5	-1.2	-0.6	1.1	1.1	1.4	1.1	-0.4	0.4	1.1
Allergy	0.7	1.7	6.0	0.9	1.7	-2.4	-2.0	-0.5	-0.1	-2.0	1.4	0.9	1.3	1.0	1.2	2.1	0.8	0.8	1.6	0.9	-1.0	0.5	-0.3	-1.0	0.7	1.7	-0.0
Hip circumference	0.7	2.8	8.4	1.9	-1.0	-2.0	-2.5	-2.9	-1.3	-2.1	-0.5	0.4	-0.2	2.0	-0.5	2.2	0.3	0.4	2.9	1.9	-2.3	0.3	1.8	-0.4	0.6	2.3	1.3
Father’s age at death	0.7	0.9	5.5	-0.5	0.8	-0.5	-0.3	-0.9	-0.1	-0.3	1.0	0.7	1.1	-1.0	0.8	-0.6	0.1	-1.0	-1.9	-2.4	1.0	-1.6	-0.5	-0.5	-0.5	-1.0	-0.6
Medication: Cholesterol lowering	0.7	1.1	5.1	0.9	0.3	0.0	-0.4	0.3	1.1	-0.1	0.3	0.1	0.4	1.5	0.5	0.8	1.7	1.8	1.2	0.8	0.5	1.7	0.6	0.4	2.3	1.5	1.2
Depression (self-reported)	0.7	0.8	4.7	-1.2	0.1	-0.2	0.3	0.2	-0.1	-0.3	0.5	0.1	0.3	-1.1	0.4	-2.2	0.2	0.1	-2.1	-1.4	0.8	0.7	-1.4	-0.9	-0.2	-1.0	-0.5
Breastfed as a baby	0.7	0.9	6.4	-0.0	0.0	-1.3	-1.6	-2.5	-1.5	-1.7	0.0	0.1	-0.0	0.0	-0.2	-0.1	-0.5	-0.5	0.2	-0.2	-1.3	-0.8	0.3	-1.3	-0.3	0.4	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.3	0.3	-0.5	1.6	0.5	1.6	0.9	1.1	-0.0	-0.3	-0.1	1.0	0.3	-0.4	1.1	0.1	-1.2	-1.2	1.8	0.8	1.2	1.8	1.0	-0.3	1.8
Medication: Paracetamol	0.7	1.1	4.1	-0.9	0.2	1.4	1.6	1.0	0.9	1.5	0.2	0.1	0.1	-1.1	0.3	-1.6	-0.2	-0.1	-1.6	-2.0	1.9	-0.5	0.3	0.3	-0.3	-1.4	0.6
Headache pain in last month	0.7	1.1	7.9	-0.4	-0.4	-0.4	-0.4	0.0	-0.4	-0.1	-0.5	-0.3	-0.6	-0.9	-0.4	-1.6	-0.7	-1.5	-1.6	-2.1	-0.4	-1.3	0.2	-0.5	-2.8	-0.9	-1.0
Wheeze or whistling in the chest in last year	0.7	1.3	5.5	-2.1	-0.1	0.5	0.1	-0.3	-0.5	0.3	0.1	0.2	-0.1	-2.1	0.1	-2.3	-0.8	-0.5	-2.2	-1.9	0.2	-1.2	-0.7	-1.0	-1.0	-1.8	-0.5
Number of children fathered	0.7	0.8	2.5	0.3	-1.4	1.1	0.8	0.9	0.0	1.0	-1.3	-1.0	-1.1	0.7	-1.1	-0.2	-0.4	-0.7	-0.0	-0.2	1.2	-0.0	1.6	1.0	0.8	0.0	0.7
Medication for pain relief, constipation, heartburn	0.7	1.2	3.9	-0.1	-1.6	-0.3	0.4	1.1	-1.3	-0.3	-1.5	-1.7	-1.6	-0.1	-1.7	-0.1	-1.7	-0.6	0.5	1.8	-0.9	0.3	-1.2	-0.2	-0.2	-0.1	-2.0
Medication: Omeprazole	0.7	0.8	2.2	1.0	0.9	0.2	0.0	-1.0	0.4	0.1	0.7	1.0	0.8	0.9	0.8	1.0	1.2	1.1	1.3	1.2	-0.5	0.9	0.9	0.5	0.0	1.5	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	3.6	-0.5	0.7	-0.0	-0.2	-0.2	1.1	0.4	0.8	0.4	1.0	-1.3	1.0	0.2	0.2	-0.9	-0.8	-0.3	-0.9	-1.1	-1.5	0.2	-1.9	-1.6	-0.6
Age at last live birth	0.7	1.1	5.2	-1.2	-0.8	0.6	0.5	0.7	-0.5	-0.1	-0.9	-1.2	-1.4	-1.1	-1.3	-1.4	-2.3	-1.3	-0.9	-0.7	0.7	-0.8	-0.6	-0.7	-0.0	-0.8	-1.6
Family relationship satisfaction	0.7	0.9	4.3	0.1	0.9	1.1	1.6	2.1	1.0	1.3	1.0	0.8	1.0	-0.2	1.1	-0.7	0.7	0.3	-1.1	-1.0	1.3	0.2	0.3	0.6	-0.3	-0.2	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.1	0.1	0.2	1.2	1.4	0.7	1.6	1.4	0.4	0.3	0.4	0.3	0.6	0.7	0.4	0.9	1.1	1.8	-0.0	1.1	0.5	1.2	-0.3	0.7	0.8
Eye problems/disorders: Glaucoma	0.7	0.8	2.7	-0.2	-1.6	-0.2	-0.1	-0.7	-0.6	-0.0	-1.3	-1.0	-1.4	-0.1	-1.5	0.3	-1.3	-0.3	1.3	1.3	-0.9	-0.1	-0.4	-0.1	0.5	0.1	-1.2
Medication: Paracetamol	0.7	1.1	4.0	-0.7	-0.5	1.5	1.6	1.0	0.6	1.6	-0.7	-0.7	-0.9	-0.6	-0.6	-1.3	-0.8	-0.3	-1.3	-1.5	2.0	-0.5	0.7	0.7	0.4	-1.1	0.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.6	0.8	-1.1	-0.6	-0.6	-1.4	-0.6	-0.5	-0.9	-0.5	-0.9	0.6	-1.0	0.7	-0.2	-0.0	1.9	1.3	-1.7	-0.2	0.9	-0.4	0.2	1.3	-0.2
Heart disease (siblings)	0.7	0.8	2.7	-0.4	-1.4	-0.5	-0.7	-0.8	-1.0	-0.4	-1.6	-1.0	-1.4	-0.3	-1.3	-1.1	0.1	-1.1	-0.5	-0.3	-1.4	-0.6	0.1	-0.7	-0.8	-1.0	0.3
Crohns Disease (2012)	0.6	1.0	3.5	1.1	-0.5	-1.3	-1.7	-1.1	-1.9	-1.8	-0.7	-0.5	-0.8	0.8	-0.8	0.6	-0.2	-0.5	0.5	0.1	-1.5	-0.2	-0.4	-1.2	-0.4	1.2	-0.9
Triglycerides	0.6	1.0	7.3	-0.1	-1.0	-0.5	-1.0	-1.3	-1.6	-0.9	-1.1	-0.8	-1.1	0.1	-1.3	-0.2	-0.4	-0.1	0.7	1.3	-2.7	-0.4	-0.5	-0.7	-0.6	0.6	-0.8
Hearing difficulty/problems: Yes	0.6	0.9	3.8	-1.7	-0.0	-0.1	-0.4	-0.2	-0.6	-0.3	-0.1	-0.1	-0.0	-1.7	0.0	-1.6	-0.7	-0.7	-1.1	-0.6	-0.8	-0.5	-1.3	-0.7	-1.9	-1.3	-0.8
Relative age of first facial hair	0.6	1.3	4.7	0.3	-0.7	1.4	1.2	0.7	-0.1	1.2	-0.9	-1.0	-0.9	-1.1	-1.0	0.4	-1.2	-2.1	-0.5	-0.1	-0.3	-2.2	-1.3	0.4	-1.2	-1.3	-1.8
Age when periods started (menarche)	0.6	1.4	5.7	-2.4	-0.1	1.6	1.8	1.7	0.4	1.5	-0.6	-1.1	-0.7	-1.9	-0.6	-1.9	-1.5	0.1	-0.9	0.0	0.6	-0.2	-0.9	0.1	-0.0	-1.6	-0.2
Supplements: Glucosamine	0.6	0.8	3.6	-0.3	0.2	1.3	0.3	0.9	-0.8	0.5	-0.1	-0.2	0.1	-0.4	-0.2	-0.1	0.0	-1.7	-1.6	-1.4	0.9	-1.3	-0.0	0.4	-0.9	-1.9	-0.1
Chronic bronchitis/emphysema (father)	0.6	0.7	2.5	0.2	1.0	1.0	0.6	0.7	0.8	0.5	1.2	0.8	1.3	0.3	1.3	0.6	1.0	0.5	-0.1	-0.8	1.6	0.4	0.3	0.6	-0.0	-0.9	0.7
Hair/balding pattern: Pattern 2	0.6	0.8	2.3	-0.8	-0.9	1.2	1.2	1.1	-0.0	0.9	-1.0	-0.6	-1.1	-0.5	-1.0	-1.5	-0.6	-0.4	-1.2	-1.1	1.5	0.1	-0.2	0.0	0.5	-1.0	-0.2
Happiness	0.6	0.7	2.6	-0.5	1.4	-0.2	0.1	0.4	0.6	-0.1	1.6	1.5	1.4	-0.5	1.4	-0.6	0.1	1.3	-0.2	-0.4	0.0	0.6	-0.0	-0.6	-0.2	1.0	0.0
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.7	-0.9	1.6	-1.5	-0.6	-1.7	0.0	-1.2	1.9	1.8	1.8	-0.9	1.5	-0.4	-0.5	0.8	0.8	0.2	-0.8	0.1	-1.1	-1.6	-0.6	0.7	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.7	0.2	-0.8	-1.1	-1.5	-1.7	-1.3	-1.4	-0.4	-0.1	-0.2	0.5	-0.2	-0.4	1.1	0.4	0.1	-0.3	-1.0	0.4	-0.1	-1.0	0.2	1.1	0.5
Loud music exposure frequency	0.6	0.6	3.1	-0.0	0.7	-0.3	-0.5	0.2	0.6	-0.2	0.7	0.4	1.0	0.6	1.1	-0.5	1.6	1.8	-0.3	-0.1	0.6	1.4	0.2	0.5	0.7	0.7	0.9
Pulse wave peak to peak time	0.6	0.7	3.8	0.9	-1.0	-0.2	-0.2	-0.3	-0.6	0.0	-1.2	-1.2	-0.9	-0.1	-1.1	0.4	-0.1	-0.8	0.6	1.0	-1.9	-0.7	-0.3	0.1	-1.3	-0.8	-0.8
Eye problems/disorders: None of the above	0.6	0.7	2.7	-1.3	1.0	-0.5	0.6	1.0	0.2	-0.2	0.5	0.1	0.4	-1.2	0.4	-0.9	-1.1	0.2	-0.9	-0.7	1.1	-0.2	-1.6	-1.2	0.1	-1.0	-1.2
Chest pain or discomfort	0.6	0.8	3.9	-0.2	0.0	-0.9	-1.1	-1.5	-0.7	-0.5	0.0	-0.1	0.3	-0.7	0.5	-1.2	1.2	-0.5	-1.3	-2.0	-0.7	-1.2	0.2	-0.6	-1.3	-0.6	0.8
Had major operations	0.6	0.7	2.2	0.9	0.4	1.3	0.1	0.3	1.2	1.0	-0.1	0.4	0.4	0.6	0.3	1.2	1.3	-0.8	-1.2	-0.9	0.7	-0.5	0.3	1.5	0.1	-0.9	1.3
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.7	0.4	-0.4	-1.5	-1.3	-1.0	-0.8	-1.6	-0.2	0.2	-0.2	1.0	-0.2	-0.5	0.9	1.0	0.5	0.2	-0.8	1.3	0.3	-0.8	0.5	1.3	0.2
Average weekly red wine intake	0.6	0.8	3.7	0.2	-0.4	0.7	0.4	1.7	1.2	0.4	-0.4	-0.2	-0.4	1.4	-0.3	0.2	0.5	0.6	0.2	1.0	1.0	1.9	0.4	1.1	1.7	0.7	0.7
Qualifications: nursing, teaching	0.6	0.9	3.0	0.1	1.3	-0.7	-1.0	-1.3	0.4	-0.8	1.7	1.7	1.7	-0.3	1.5	-0.0	1.1	0.7	-0.1	-0.1	-1.0	0.3	-0.9	-0.6	-0.5	0.5	0.1
Back pain experienced in last month	0.6	0.8	5.4	-0.7	0.5	-0.6	-1.6	-2.3	-0.7	-0.8	1.1	0.7	1.0	-0.7	0.9	0.0	0.7	-0.2	-0.5	-0.4	-1.3	-0.9	-0.1	-0.5	-0.2	-0.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	6.7	-0.1	0.6	0.5	-0.2	-0.6	1.0	0.3	0.4	0.4	0.2	0.6	0.1	0.7	-0.0	2.0	2.5	2.6	-0.8	1.8	0.6	0.7	1.3	1.6	0.8
Wears glasses or contact lenses	0.6	0.7	2.7	1.0	0.1	1.1	1.4	0.1	1.6	1.6	0.3	0.9	0.8	0.4	0.6	0.4	1.3	0.2	-0.3	-0.1	0.6	0.0	0.6	1.4	-0.5	-0.1	0.8
Myopia	0.6	0.8	5.0	0.8	-0.8	0.5	1.0	0.0	-0.2	1.0	-0.8	-0.6	-0.5	0.2	-0.5	0.3	0.3	-0.6	0.5	1.0	-1.0	-0.5	2.1	1.0	-2.2	-0.2	0.7
Crohns Disease (2017)	0.5	1.1	5.4	0.3	-0.9	-0.9	-1.9	-2.3	-2.0	-1.8	-0.6	-0.4	-0.6	0.3	-0.7	0.1	-0.4	-0.1	0.6	0.5	-1.9	-0.4	-0.4	-1.0	0.0	1.3	-0.5
Major Depression (MDD)	0.5	0.6	2.2	0.5	-0.9	0.8	0.5	0.4	-0.3	0.4	-1.3	-1.1	-1.5	0.9	-1.4	0.4	-0.9	0.1	0.9	0.9	0.1	0.4	0.7	0.5	0.9	1.0	0.0
Fasting Glucose	0.5	0.6	3.5	1.0	-0.0	0.8	0.6	0.6	0.3	0.9	-0.5	-0.0	-0.3	1.1	-0.2	0.4	0.4	0.3	0.9	0.2	1.0	0.4	1.9	1.4	0.6	1.0	0.8
Blood Platelet Count	0.5	5.6	23.7	-1.2	0.0	-2.7	-2.9	-4.4	-2.5	-2.1	-0.4	-0.5	0.0	-2.5	-0.7	0.4	-1.7	-2.5	-0.1	-0.1	-4.9	-3.7	-2.8	-2.2	-3.4	-1.7	-2.5
Number of treatments/medications taken	0.5	0.9	2.6	-1.4	1.1	-0.4	-0.9	-0.7	0.9	-0.6	1.3	1.6	1.1	-0.4	1.2	-1.5	0.9	1.3	-0.5	-0.6	0.1	1.1	-0.2	-0.9	0.0	0.2	0.6
Sensitivity / hurt feelings	0.5	0.9	3.3	0.2	0.3	-0.5	-1.4	-0.5	-1.2	-1.0	0.5	0.6	0.8	-0.3	0.6	-0.5	1.2	-0.8	-1.8	-1.7	-0.9	-1.1	-0.9	-0.6	-1.2	-0.7	-0.4
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.3	1.1	-0.2	-0.3	-0.9	-0.6	-0.1	-0.6	-0.1	-0.1	-0.0	1.5	-0.4	1.8	0.2	-0.2	1.0	1.1	-0.3	0.4	1.0	0.5	1.0	0.8	0.8
Vitamin and mineral supplements	0.5	0.6	3.8	-1.6	0.3	-0.6	-0.1	0.3	0.1	-0.0	0.2	0.5	0.1	-1.3	0.1	-1.9	-1.3	0.1	-0.6	-0.7	-0.7	-0.3	0.1	-0.9	-1.3	-0.5	-0.5
Taking other prescription medications	0.5	0.8	2.5	-0.2	1.2	-1.0	-1.4	-1.0	0.3	-1.0	1.4	1.4	1.2	-0.1	1.1	-0.0	0.1	0.6	0.4	0.4	-1.6	0.3	-0.3	-0.5	-1.3	1.0	-0.5
Had menopause	0.5	0.6	2.4	-0.6	1.5	0.2	0.2	0.1	1.2	0.2	1.6	1.2	1.5	-0.4	1.5	0.6	0.8	0.7	0.4	0.3	0.6	0.5	-0.2	-0.1	0.4	-0.4	0.5
Mouth/teeth dental problems	0.5	0.8	4.3	0.2	-0.5	0.5	0.9	0.8	-0.4	0.4	-0.5	-0.6	-0.5	0.8	-0.7	0.5	-0.5	1.1	1.4	1.4	0.7	1.0	0.7	0.6	2.1	1.3	0.3
Hair/balding pattern: Pattern 3	0.5	0.8	2.5	0.5	1.6	-0.9	-0.0	-0.5	0.7	-0.4	1.4	1.5	1.5	0.5	1.5	-0.1	1.2	1.2	-0.0	-0.2	0.4	0.7	0.7	-0.4	0.3	0.8	0.7
Noisy workplace	0.5	0.7	1.8	0.2	0.1	1.1	1.1	1.0	1.4	1.2	-0.4	-0.4	-0.3	0.7	-0.2	0.6	-0.2	0.3	1.2	0.9	1.2	1.0	1.0	1.1	0.6	-0.4	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	5.5	0.5	-0.3	0.2	0.5	-1.3	-0.2	0.2	-0.0	0.3	-0.1	-0.1	-0.1	-0.4	0.1	-0.9	-0.9	-2.3	1.7	-0.9	0.7	-0.3	-0.0	-0.3	0.2
Length of working week for main job	0.5	0.5	2.5	-1.0	-0.0	-0.8	-1.3	-0.5	-0.9	-1.0	0.4	0.4	0.3	-0.9	0.1	-0.5	-0.2	0.1	-0.3	-0.1	-1.6	-0.9	-0.3	-1.2	-0.1	-0.7	0.3
Glaucoma (self-reported)	0.5	0.6	3.9	0.7	-0.6	-0.0	0.0	0.0	0.3	0.2	-0.4	-0.3	-0.6	0.7	-0.6	1.5	-0.5	0.0	2.0	1.7	-0.5	0.3	0.0	0.5	0.8	0.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.3	-0.1	0.0	1.2	0.5	0.4	-0.0	0.7	0.4	0.6	0.5	-0.8	0.5	0.1	-0.4	-0.9	-1.4	-1.4	0.7	-1.5	-0.4	0.5	-0.9	-1.3	-0.5
Number of full brothers	0.5	0.7	3.6	0.6	-0.4	0.6	0.7	1.2	0.4	0.6	-0.3	-0.4	-0.1	0.9	0.1	0.3	1.2	0.5	-0.3	-0.5	1.9	1.0	-0.1	1.0	1.7	0.3	0.8
Age at first live birth	0.5	0.9	3.0	-0.1	-1.5	1.1	0.4	0.4	-0.9	0.4	-1.4	-1.7	-1.5	-0.4	-1.6	-0.3	-1.1	-1.4	-0.4	-0.1	-0.1	-1.2	-0.1	0.2	0.2	-0.7	-0.9
Neck or shoulder pain in last month	0.5	0.6	4.2	-0.1	0.8	0.8	-0.2	-0.3	0.3	0.4	0.6	0.5	0.5	-0.6	0.5	0.1	-0.2	-1.1	-1.3	-2.0	0.9	-1.6	-0.0	-0.0	-0.1	-1.4	0.2
Suffer from ‘nerves’	0.5	0.7	3.8	-1.6	-0.2	0.2	-0.2	0.6	0.2	-0.2	0.2	-0.1	0.1	-1.1	0.2	-1.9	0.5	0.1	-1.6	-1.1	0.3	0.1	-1.5	-0.7	0.6	-1.3	-0.2
Supplements: Vitamin C	0.5	0.6	4.9	0.5	-0.4	0.8	0.8	0.9	0.3	0.3	-0.5	-0.5	-0.6	1.1	-0.5	0.3	-0.2	-0.2	-0.1	-0.1	2.2	1.0	0.8	0.9	1.5	0.2	0.6
Smoking status: Previous	0.5	0.8	2.8	0.8	-1.0	0.4	0.4	0.3	0.4	0.8	-1.0	-0.6	-0.8	1.3	-0.6	1.1	0.4	0.4	0.8	0.7	0.8	0.8	1.1	1.4	1.7	0.9	1.5
Loneliness, isolation	0.5	0.6	2.6	1.4	-0.5	1.1	0.8	0.9	0.8	0.9	-0.4	-0.1	-0.0	1.0	0.0	1.3	1.6	0.1	0.2	0.9	-0.2	0.4	-0.1	1.3	-0.3	-0.2	0.7
Osteoporosis (self-reported)	0.5	0.6	3.0	-0.2	1.7	-0.5	-0.7	-0.6	0.4	-0.4	1.4	1.5	1.4	-0.4	1.2	0.6	0.4	0.0	0.5	0.2	-0.6	-0.1	-0.0	-0.6	-0.9	-0.1	0.3
Smoking status: Current	0.5	0.8	4.4	0.2	-0.4	-0.4	-0.9	-0.5	-0.6	-0.3	-0.9	-0.8	-0.6	-0.4	-0.6	0.2	-0.7	-2.1	-0.9	-1.2	-0.3	-1.9	0.1	-0.1	-1.2	-1.7	-0.6
Commuting to job workplace: Public transport	0.5	0.6	2.6	-0.9	-0.1	-0.0	-0.4	-0.4	-0.8	-0.1	-0.1	-0.3	-0.1	-1.3	-0.2	-1.6	-0.8	-0.7	-0.9	-1.2	-0.7	-1.4	-0.1	-0.7	-1.3	-0.9	-0.7
Fractured/broken bones in last 5 years	0.5	0.6	3.0	-0.9	-0.7	0.6	0.8	1.0	-0.3	0.4	-0.9	-0.9	-0.9	-0.2	-1.0	-0.8	-0.5	-0.1	-0.7	0.7	0.7	0.7	-1.2	-0.0	1.7	-0.1	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.5	0.2	0.6	-0.1	-0.8	-1.5	-0.2	-0.3	0.5	0.6	0.5	0.2	0.4	0.7	0.5	0.7	1.2	1.4	-1.6	0.3	0.4	0.1	-0.4	1.3	0.7
Schizophrenia (2018)	0.4	0.9	4.3	0.2	0.4	-1.4	-1.4	0.0	-0.0	-1.8	0.1	0.3	-0.0	1.1	0.1	0.3	0.2	1.2	1.0	0.1	0.5	1.8	-0.3	-0.8	2.1	1.2	-0.1
Alzheimer’s Disease (in father)	0.4	0.4	2.2	1.5	-0.5	0.9	0.4	0.3	0.2	0.9	-0.4	-0.4	-0.4	0.9	-0.2	0.9	0.6	-0.0	0.4	0.5	-0.6	-0.3	0.9	1.1	-0.0	0.3	0.5
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.6	0.2	1.4	0.2	0.7	0.1	1.4	0.8	1.4	1.5	1.5	-0.2	1.6	-0.3	1.0	0.9	0.1	0.9	-0.8	0.8	0.2	0.5	-1.6	0.7	0.6
Body Mass Index (BMI) (2010)	0.4	0.5	2.2	0.3	-0.4	-1.4	-1.1	-0.9	-1.1	-1.2	-0.4	-0.1	-0.1	-0.0	-0.2	0.3	0.5	0.2	0.1	0.2	-1.5	-0.3	-1.2	-0.8	-0.2	0.6	-0.6
Neuroticism (2016)	0.4	0.6	1.8	-0.1	1.0	1.4	0.6	1.4	0.9	0.8	0.6	0.4	0.6	-0.0	0.8	-0.5	0.8	-0.0	-1.1	-0.8	1.2	0.6	-0.2	1.0	-0.2	-0.8	0.5
Schizophrenia (2014)	0.4	0.9	3.0	0.8	-0.7	-1.4	-1.4	-0.3	-0.8	-1.7	-0.8	-0.5	-0.9	1.6	-0.8	0.5	0.1	0.5	1.2	0.3	-0.0	1.4	0.4	-0.5	1.5	1.3	-0.2
BMI	0.4	2.2	6.2	-1.4	-1.3	-1.9	-2.5	-2.1	-2.0	-1.9	-1.1	-0.2	-0.8	-1.2	-0.9	-1.9	-0.8	-1.2	-0.7	-1.2	-2.3	-1.2	-0.0	-1.7	-2.2	-0.8	-0.2
Average weekly spirits intake	0.4	0.5	1.5	0.5	-1.0	-0.4	0.0	-0.8	-0.5	-0.4	-1.0	-1.2	-0.9	0.2	-1.0	1.2	-0.5	-0.6	1.0	0.6	0.4	-0.2	-0.9	-0.2	1.1	-0.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.3	0.1	0.7	-0.0	-1.0	-1.5	0.3	-0.2	0.9	0.9	1.2	-0.2	0.9	0.7	1.5	0.4	0.4	-0.2	-0.6	-0.1	0.1	0.2	-0.6	-0.4	0.9
Current tobacco smoking	0.4	0.6	2.8	0.1	0.1	-0.7	-1.1	-0.7	-0.4	-0.4	-0.3	-0.2	0.0	-0.5	-0.0	0.2	-0.0	-1.6	-1.0	-1.2	-0.6	-1.7	-0.2	-0.2	-1.2	-1.6	-0.3
Maternal smoking around birth	0.4	0.6	1.6	-0.7	1.1	-0.7	-0.6	-0.2	0.7	-0.4	1.0	1.1	1.0	-0.9	1.0	0.2	0.1	-0.5	0.2	-0.6	-0.5	-0.6	0.2	-1.0	-1.3	-1.2	0.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.5	-0.2	-0.6	0.5	0.4	0.0	0.8	0.5	-0.0	-0.2	-0.1	0.4	-0.2	0.3	-0.5	1.2	1.3	1.6	0.0	1.1	0.3	0.5	1.2	0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	-1.3	0.2	0.8	-0.2	0.4	-0.7	0.1	-0.0	-0.2	-0.1	-0.8	0.1	-1.1	-0.4	-0.3	-1.5	-1.5	0.5	-0.2	-0.6	-0.2	0.1	-1.0	0.2
Worrier / anxious feelings	0.4	0.8	2.9	1.2	0.5	0.9	-0.0	-0.3	0.5	0.7	0.4	0.6	0.5	1.2	0.7	0.7	1.7	0.8	0.5	0.2	-0.1	0.6	1.5	1.3	0.2	1.2	1.6
Falls in the last year	0.4	0.6	2.8	-0.8	0.4	1.1	0.7	0.5	0.5	0.9	0.4	0.3	0.5	-0.8	0.5	-1.0	0.3	-0.4	-1.7	-1.0	0.6	-0.6	0.4	0.3	-0.5	-1.0	0.8
Pulse rate	0.4	0.7	4.2	-1.1	-0.4	-1.2	-0.9	-0.8	-0.5	-1.4	0.0	0.1	-0.1	-0.4	-0.3	-2.0	-0.4	0.5	-0.8	-0.3	-0.5	0.7	-0.8	-1.8	0.2	0.5	-0.7
Arm fat mass (right)	0.4	1.5	5.9	-0.3	-0.9	-2.1	-2.4	-2.3	-1.9	-2.1	-0.5	-0.1	-0.3	-0.2	-0.7	0.2	-0.8	-0.9	0.9	0.2	-1.9	-0.9	0.2	-1.5	-0.5	0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.8	-0.3	-0.5	0.5	0.7	-0.5	-0.7	0.5	-0.4	-0.3	-0.5	-0.8	-0.6	-0.0	-1.4	-1.7	-0.8	-0.7	0.3	-1.5	-0.1	0.2	-1.3	-1.6	-0.7
Exposure to tobacco smoke outside home	0.4	0.5	2.8	0.1	-0.5	-1.0	-1.7	-0.9	-0.6	-1.0	-0.8	-0.6	-0.6	0.1	-0.6	0.4	0.0	-1.1	-0.1	-0.1	-1.4	-0.8	-0.1	-0.3	-0.9	0.1	-0.3
Health satisfaction	0.4	0.5	1.8	-0.4	1.4	0.1	0.0	-0.1	0.4	0.2	1.2	1.1	1.3	-0.4	1.2	-0.6	0.6	0.4	-0.8	-1.0	0.5	-0.0	0.3	-0.1	-0.2	0.2	0.5
Medication: Ibuprofen	0.4	0.5	3.8	0.5	0.1	0.5	1.0	-0.9	0.4	0.6	0.3	0.6	0.3	0.2	0.3	-0.0	0.2	-0.2	-0.4	-1.7	2.0	-0.5	1.0	0.1	0.3	0.1	0.6
Alcohol intake frequency.	0.4	1.0	3.5	-0.4	-0.0	-1.7	-1.2	-1.4	-1.6	-1.3	0.0	-0.1	-0.1	-0.9	0.0	-1.4	-0.4	-0.5	-0.5	-1.3	-1.4	-1.2	0.8	-1.3	-1.9	-0.2	-0.5
Overall health rating	0.4	0.8	3.5	-0.9	0.2	0.7	-0.3	-0.3	0.6	0.7	0.5	0.5	0.8	-0.8	1.0	-1.2	1.4	-0.2	-1.9	-1.7	0.2	-0.6	0.2	0.4	-0.9	-1.3	1.4
Breast cancer (self-reported)	0.4	0.4	2.7	-0.7	-0.2	-0.3	-0.2	-0.1	0.3	0.0	-0.1	-0.4	0.1	-0.9	-0.0	0.1	-0.9	-0.4	0.8	0.9	-1.5	-0.5	-0.1	-0.2	-1.7	-0.6	-0.6
Arm fat mass (left)	0.4	1.5	5.9	-0.2	-0.9	-2.1	-2.4	-2.3	-1.9	-2.2	-0.5	-0.1	-0.3	-0.1	-0.7	0.3	-0.8	-0.8	1.0	0.4	-2.0	-0.8	0.2	-1.4	-0.5	0.2	-0.0
Number of self-reported non-cancer illnesses	0.4	0.7	2.8	0.7	0.3	0.2	-0.3	-0.0	0.9	0.3	0.7	0.6	0.8	0.8	0.9	0.8	1.7	1.2	1.5	0.8	-0.1	1.2	0.6	0.7	0.3	0.7	1.0
Average weekly champagne plus white wine intake	0.4	0.5	2.3	0.5	-0.6	1.1	1.2	1.5	0.8	1.3	-0.2	0.1	0.1	0.5	0.1	-0.5	0.3	0.3	-0.4	0.0	0.8	0.7	0.5	1.4	0.1	0.4	0.3
Mother’s age at death	0.4	0.6	2.0	1.4	-0.9	0.6	0.0	-0.1	0.1	0.6	-1.0	-0.9	-0.7	1.1	-0.7	1.3	1.0	-0.1	0.6	0.6	0.1	0.2	0.1	1.3	0.6	-0.0	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.0	0.2	-0.6	1.4	0.6	0.1	-0.2	0.9	-0.6	-0.7	-0.4	0.1	-0.3	0.3	1.1	-0.4	-0.7	-0.3	0.5	-0.3	-0.3	0.9	1.1	-0.5	0.7
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.4	-0.9	1.1	-0.0	-0.1	-1.2	1.1	0.1	1.0	1.0	0.8	-0.4	0.8	-0.0	0.1	1.0	0.6	0.4	0.1	0.8	-0.1	-0.4	0.8	-0.1	1.1
Medication: Atorvastatin	0.4	0.5	2.4	-1.1	-0.2	-0.6	-1.0	-0.3	-0.9	-0.9	-0.3	-0.5	-0.6	-0.3	-0.4	-1.5	-0.2	0.7	-0.0	0.1	-0.5	0.8	-0.1	-1.0	0.7	1.0	0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	1.3	1.1	-0.9	0.1	-0.3	0.5	-0.7	-0.3	-1.0	-0.7	-0.9	1.0	-0.8	0.4	0.2	0.0	0.3	0.6	-0.2	0.4	0.5	0.2	1.1	0.5	0.5
Ulcerative Colitis (UC)	0.3	0.6	2.5	0.9	0.0	1.0	0.7	1.5	1.1	0.7	0.1	0.5	0.1	0.9	0.2	-0.0	0.8	0.2	-0.6	-1.0	1.6	1.0	0.1	1.0	0.1	0.0	0.5
Age at First Birth	0.3	0.4	1.0	-0.4	-0.9	0.4	0.4	0.4	-0.7	0.1	-0.7	-1.0	-0.6	-0.5	-0.7	-0.5	-0.1	0.0	-0.6	-0.8	1.0	-0.3	-1.0	-0.1	0.9	-0.5	-0.3
HbA1C	0.3	0.4	1.7	-0.1	-0.7	0.3	1.0	0.3	0.4	0.7	-0.4	-0.3	-0.5	0.4	-0.5	-0.6	-0.1	1.0	0.2	0.2	0.7	0.6	1.3	0.3	0.5	0.8	0.7
Ulcerative Colitis	0.3	0.5	2.5	1.5	-0.1	-0.1	0.7	1.6	0.8	0.0	0.3	0.8	0.3	1.2	0.4	0.5	0.9	0.3	0.1	-0.3	0.9	0.9	0.3	0.4	-0.1	0.7	-0.1
Blood Eosinophil Count	0.3	2.2	6.7	0.1	-2.6	1.8	0.6	1.3	-1.6	1.2	-2.4	-2.6	-2.1	-0.0	-2.1	0.2	-0.2	-1.8	-0.8	-0.6	0.2	-2.1	1.4	1.3	1.2	-0.7	0.9
Neuroticism	0.3	0.8	4.3	1.3	0.9	1.1	0.1	1.1	0.7	0.7	0.8	1.1	0.9	1.0	1.1	0.7	2.1	-0.0	-0.5	-0.5	0.1	0.3	0.7	1.2	-0.4	0.4	1.3
Medication for hormone replacement therapy	0.3	0.4	1.3	0.1	-0.8	0.1	0.3	-0.0	-0.4	0.2	-1.1	-0.9	-1.1	0.7	-1.0	0.3	-0.8	-0.6	0.3	0.4	0.6	0.2	0.7	0.4	1.0	0.3	0.1
Medication: Co-codamol	0.3	0.3	4.0	0.1	0.1	0.3	-0.1	-0.0	0.1	-0.1	-0.1	0.2	-0.3	0.7	-0.3	0.7	-0.4	-0.1	-0.0	-0.7	2.0	0.4	0.3	0.3	1.2	-0.3	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.5	0.9	0.6	0.4	0.6	0.7	1.2	0.7	0.5	0.3	0.7	0.9	0.8	0.1	1.6	0.6	-0.8	-0.8	1.3	0.9	0.5	0.9	0.1	-0.0	0.9
Multivitamins +/- minerals	0.3	0.3	2.0	0.6	-0.1	0.4	-0.2	-0.3	-0.1	-0.1	-0.0	-0.3	0.1	0.5	-0.0	1.3	1.4	0.0	0.3	0.6	0.3	0.4	-1.0	0.3	1.1	-0.2	0.3
Body mass index (BMI)	0.3	1.1	5.2	-0.2	-1.0	-2.0	-2.3	-1.8	-1.4	-1.9	-0.5	0.0	-0.3	0.0	-0.6	0.2	-0.7	-0.5	1.0	0.2	-1.6	-0.6	0.5	-1.2	-0.4	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.4	1.1	0.4	0.7	0.9	0.6	1.3	1.0	0.2	-0.0	0.4	0.9	0.6	0.3	1.6	0.7	0.1	0.0	0.8	1.1	0.7	1.0	-0.1	-0.2	1.0
Time employed in main current job	0.3	0.3	0.8	-0.8	0.9	0.0	-0.5	-0.8	0.1	-0.2	0.9	0.8	0.8	-0.7	0.8	-0.2	-0.2	0.1	-0.8	-0.6	-0.1	-0.7	-0.3	-0.2	0.1	0.1	0.1
Mouth/teeth dental problems: Dentures	0.3	0.6	2.4	-0.4	-0.0	-0.7	-0.6	-1.5	-0.3	-0.3	-0.1	-0.3	-0.1	-0.9	0.0	-0.6	-0.2	-1.2	-1.2	-1.3	-0.1	-1.4	-0.5	-0.6	-0.7	-1.2	-0.2
Lung cancer (father)	0.3	0.3	1.3	-0.1	-0.7	0.9	0.7	1.2	0.7	0.9	-0.6	-0.6	-0.4	0.2	-0.4	0.3	-0.2	0.2	0.1	0.5	0.5	0.2	-0.2	1.1	0.5	-0.3	-0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.3	0.8	-0.4	0.9	0.5	1.0	0.5	0.9	-0.6	-0.5	-0.6	0.5	-0.3	0.4	0.3	-0.9	-0.4	-0.4	0.2	-0.4	0.6	1.1	-1.1	-0.3	0.3
Birth weight	0.3	0.7	4.1	0.2	-0.5	0.7	0.5	0.3	0.0	0.5	-0.3	-0.4	-0.3	-0.4	-0.2	-0.3	0.1	-1.4	-1.5	-2.0	1.5	-1.0	-0.5	0.4	-0.6	-1.5	-0.4
Comparative body size at age 10	0.3	0.8	2.5	0.2	0.5	-0.8	-1.1	-0.8	-0.1	-1.0	0.5	1.1	0.7	1.0	0.6	-0.4	1.4	1.0	-0.7	-0.2	0.2	1.1	0.5	-0.1	1.6	1.3	1.5
Heart disease (mother)	0.3	0.3	1.5	-0.1	1.1	-0.2	-0.1	0.2	0.9	-0.3	0.9	1.2	0.7	0.3	0.8	-0.3	0.3	0.6	-0.3	-0.4	0.2	0.5	0.9	-0.5	0.3	0.3	0.4
Whole body fat mass	0.3	1.5	5.5	-1.0	-0.7	-1.9	-2.4	-2.2	-1.7	-2.1	-0.5	-0.3	-0.3	-0.9	-0.7	-0.0	-1.2	-1.0	0.6	-0.1	-1.5	-1.1	-0.6	-1.7	-0.4	-0.8	-0.4
Leg fat mass (right)	0.3	1.3	4.7	-1.2	-0.8	-1.7	-2.2	-1.9	-1.4	-1.8	-0.6	-0.4	-0.4	-1.0	-0.7	-0.1	-1.2	-1.1	0.5	-0.2	-1.3	-1.2	-0.4	-1.5	-0.5	-1.0	-0.1
Leg pain on walking	0.3	0.3	3.1	-0.1	-0.3	-0.1	-0.6	-0.6	0.0	-0.2	-0.3	-0.4	-0.1	0.5	-0.2	0.6	0.1	0.2	-0.4	-0.4	0.9	-0.3	0.5	0.6	1.8	-0.0	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.5	-0.3	-0.7	-0.4	-0.4	-0.8	-0.3	-0.5	-0.6	-0.3	-0.4	0.4	-0.5	-0.2	0.3	0.5	0.5	0.1	0.4	0.7	0.4	-0.3	1.6	0.3	0.8
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	0.7	-1.1	0.4	0.3	0.2	-0.9	0.1	-1.0	-0.8	-1.0	0.4	-1.0	0.8	-0.2	-1.0	0.3	0.4	0.1	-0.1	0.0	0.5	-0.5	-0.3	0.1
Irritability	0.3	0.5	1.7	0.8	0.6	-0.7	-1.3	-1.1	-0.7	-1.1	0.7	0.2	0.6	0.3	0.7	0.5	0.9	-0.7	-0.1	-0.4	-1.0	-0.3	-0.4	-0.4	-0.9	0.3	-0.3
Commuting to job workplace: Cycle	0.3	0.4	2.5	-0.9	-0.6	0.5	0.4	-0.3	-0.2	0.4	-0.7	-0.9	-0.7	-0.5	-0.8	-0.3	-0.4	0.2	-0.0	0.6	0.4	0.0	-1.0	-0.0	1.6	-0.5	-0.3
Pack years of smoking	0.3	0.5	1.5	-0.2	0.3	0.5	0.7	0.1	0.7	0.8	0.4	0.7	0.4	0.1	0.7	-1.1	1.2	1.2	-0.7	-0.6	0.6	0.8	0.7	0.4	0.1	0.6	1.2
Leg fat mass (left)	0.3	1.2	4.5	-1.1	-0.9	-1.7	-2.1	-1.7	-1.4	-1.8	-0.7	-0.4	-0.4	-0.8	-0.8	-0.0	-1.2	-0.9	0.6	-0.0	-1.3	-1.0	-0.3	-1.4	-0.2	-0.9	-0.1
Bipolar Disorder (2018)	0.2	0.3	1.2	-0.0	-1.1	0.1	0.2	-0.2	-0.2	0.4	-0.7	-0.7	-0.8	0.0	-0.6	-0.0	-0.7	-0.2	0.6	0.9	-0.9	-0.2	0.3	0.4	-0.1	0.3	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	2.5	0.1	-0.4	-1.0	-1.0	-0.1	-0.1	-1.1	-0.2	-0.2	-0.5	0.9	-0.4	0.2	-0.2	0.9	1.2	0.6	-0.2	1.4	-0.2	-0.4	1.6	1.1	-0.2
Depressed Affect (Nagel 2018)	0.2	0.5	3.3	0.5	-0.3	1.4	1.0	1.8	0.7	1.2	-0.5	-0.2	-0.3	0.4	-0.1	0.2	0.6	-0.7	-0.7	-0.1	0.2	0.0	-0.1	0.6	-0.6	-0.5	0.1
Neuroticism (Nagel 2018)	0.2	0.5	3.6	1.0	-0.1	0.7	-0.0	1.2	-0.1	0.2	-0.0	0.3	0.2	0.7	0.3	0.1	1.9	-0.7	-1.5	-1.0	0.1	0.1	-0.1	0.8	-0.4	-0.0	0.7
Worry (Nagel 2018)	0.2	0.4	3.0	0.9	-0.4	0.2	-0.4	1.0	-0.6	-0.3	-0.4	-0.1	-0.3	0.8	-0.1	-0.3	1.7	-0.3	-1.2	-0.8	-0.5	0.1	-0.2	0.2	0.2	0.2	0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.7	0.9	-0.2	0.3	0.1	0.1	-0.4	0.4	-0.1	0.1	0.0	0.1	0.2	-0.1	0.4	-0.7	-1.0	-0.8	-0.9	-0.9	-0.1	0.2	-1.3	0.2	-0.0
Lupus	0.2	0.4	1.9	0.3	0.1	0.1	0.4	-1.0	0.3	-0.2	0.1	-0.1	-0.1	0.3	-0.3	0.8	-1.1	0.3	1.4	1.1	0.3	0.2	0.4	-0.3	1.2	0.4	-0.2
Rheumatoid Arthritis	0.2	0.3	0.9	-0.6	-0.6	0.1	0.4	0.3	-0.5	0.0	-0.7	-0.8	-0.9	-0.2	-0.7	-0.5	-0.9	0.2	0.5	0.8	-0.7	0.2	0.3	-0.3	0.2	0.2	-0.2
Blood White Count	0.2	1.6	7.0	0.1	1.1	-0.9	-2.1	-0.8	0.3	-1.0	0.8	1.2	1.2	0.8	1.2	0.4	1.6	1.5	1.3	1.3	-2.6	0.7	1.1	0.1	0.0	1.6	1.9
Heel T-Score	0.2	1.7	8.4	1.6	-0.7	0.9	0.8	0.7	0.6	1.0	-0.6	-0.4	-0.3	2.0	-0.1	-0.2	2.9	1.9	1.2	1.5	-0.8	2.4	1.6	1.2	0.7	1.2	1.6
Smoking Status	0.2	0.5	1.7	0.6	-0.6	-0.9	-1.0	-0.5	-0.6	-0.5	-1.1	-0.6	-0.8	0.5	-0.8	0.5	-0.7	-1.3	-0.0	-0.8	-0.0	-1.0	1.2	0.2	0.0	-0.0	0.3
Severe depression (siblings)	0.2	0.2	1.1	-0.7	-0.1	-0.5	-0.6	-0.7	-0.6	-0.4	-0.4	-0.2	-0.3	-0.6	-0.2	-1.0	0.2	-0.3	-0.7	-0.8	-0.3	-0.4	-0.0	-0.6	-0.2	-0.1	-0.0
Pack years adult smoking proportion	0.2	0.4	2.2	-0.4	-0.1	0.5	0.5	0.2	0.4	0.8	-0.1	0.3	-0.1	-0.2	0.3	-1.5	1.0	0.8	-0.9	-0.6	0.1	0.5	0.6	0.4	-0.4	0.4	0.9
Trunk fat mass	0.2	1.0	3.6	-1.2	-0.6	-1.4	-1.9	-1.8	-1.4	-1.7	-0.4	-0.2	-0.1	-0.9	-0.5	-0.3	-0.9	-0.8	0.2	-0.5	-0.8	-1.0	-0.7	-1.4	0.1	-0.9	-0.2
Qualifications: None of the above	0.2	0.5	2.7	-0.2	-1.0	0.3	0.4	0.2	-0.6	0.3	-1.5	-1.6	-1.6	0.1	-1.3	-0.5	-0.5	-0.3	-0.1	0.3	-0.1	0.4	-0.3	0.2	0.1	-0.4	-0.2
Fluid intelligence score	0.2	0.4	2.7	0.0	0.1	-0.7	0.0	-0.7	-0.0	-0.0	0.1	0.2	0.1	-0.4	0.2	-0.5	-0.1	-0.0	0.2	1.0	-1.6	0.2	-0.3	-0.4	-1.6	0.8	-0.4
Neuroticism score	0.2	0.4	1.7	1.2	-0.5	1.2	0.3	1.1	-0.1	0.6	-0.1	-0.2	-0.0	0.8	0.1	0.5	1.3	-0.7	-0.4	-0.5	0.1	-0.1	0.3	1.2	-0.3	-0.2	0.7
Exposure to tobacco smoke at home	0.2	0.2	1.1	-0.1	-0.3	-0.4	-1.0	0.6	0.1	-0.3	-0.4	-0.5	-0.3	0.3	-0.1	0.9	0.4	-0.8	0.1	-0.0	-0.1	-0.3	-0.6	0.2	0.5	-0.2	0.3
Tense / ‘highly strung’	0.2	0.3	4.0	0.9	-0.3	0.2	-0.5	0.1	-0.4	-0.4	-0.1	-0.1	0.1	0.7	0.1	-0.2	2.0	-0.1	-0.7	-0.4	-0.7	0.4	-0.3	0.0	-0.5	-0.1	0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	-0.2	0.6	0.5	0.5	-0.2	0.4	0.6	0.6	0.2	0.9	-0.8	0.6	0.2	0.3	0.1	0.7	0.7	-0.6	-0.3	-0.8	0.2	-0.7	-0.4	-0.7
Migraine (self-reported)	0.2	0.2	0.9	-0.0	0.3	0.8	0.6	0.2	0.5	0.7	-0.1	0.2	0.3	0.1	0.1	-0.1	0.9	0.5	-0.5	0.3	0.1	0.3	-0.7	0.7	0.5	-0.3	0.3
Pulse rate, automated reading	0.2	0.7	4.8	-1.3	0.2	-0.3	-0.2	0.2	0.9	-0.3	0.4	0.5	0.2	0.0	0.2	-2.2	0.0	0.9	-0.8	-0.0	0.2	1.4	0.8	-0.7	1.2	0.9	1.0
Mood swings	0.2	0.4	2.3	0.3	-0.8	1.3	0.3	1.5	-0.1	0.7	-0.5	-0.7	-0.6	0.3	-0.5	0.5	-0.3	-1.1	-0.4	-0.2	0.4	-0.4	-0.2	1.1	-0.2	-0.8	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.8	1.1	-0.1	-0.6	-0.6	-0.4	0.0	-0.5	-0.1	0.6	-0.2	0.8	-0.1	0.9	-0.3	-0.0	1.3	0.2	-0.3	-0.1	1.1	-0.2	0.1	0.6	0.6
Risk taking	0.2	0.3	0.9	0.6	0.4	-0.7	-0.7	-0.6	-0.1	-0.7	-0.0	0.2	-0.0	0.9	0.1	0.5	0.9	0.1	0.3	-0.0	0.2	0.5	0.7	-0.3	0.9	0.5	0.7
Supplements: Calcium	0.2	0.2	1.1	0.3	0.8	-0.1	-0.2	-0.4	0.3	-0.3	0.8	0.6	0.8	0.1	0.6	1.1	0.0	-0.5	0.4	0.3	-0.3	-0.3	-0.5	-0.1	0.0	-0.1	-0.4
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.8	0.4	-0.2	0.6	1.1	0.2	0.4	1.2	-0.4	-0.3	-0.2	-0.2	-0.1	0.1	-0.3	-0.9	-0.3	0.6	-0.7	-0.6	0.0	0.5	-1.3	-0.3	-0.2
Irritable Bowel Disease (IBD)	0.1	0.2	1.1	0.9	-0.2	-0.0	-0.9	-0.7	-0.6	-0.8	0.1	0.4	0.0	0.7	-0.0	0.0	0.5	0.3	-0.1	-0.5	-0.4	0.4	-0.2	-0.2	-0.2	1.0	-0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	1.0	-0.3	-0.2	-0.0	0.0	-0.2	0.1	0.0	-0.6	-0.2	-0.5	0.2	-0.6	-0.2	-0.0	0.3	0.3	0.6	-0.4	0.3	0.1	-0.1	0.3	1.0	0.2
Tanning	0.1	1.8	6.2	0.8	-0.9	2.5	2.1	1.5	0.6	2.5	-0.8	-0.5	-0.5	-0.2	-0.4	0.9	0.2	-1.7	-1.1	-0.9	1.1	-1.9	1.4	2.0	-1.2	-1.7	0.8
Fed-up feelings	0.1	0.2	0.6	0.5	-0.8	-0.4	-0.5	-0.0	-0.2	-0.1	-0.3	-0.3	-0.1	0.1	-0.1	0.7	0.8	-0.7	0.2	0.1	-0.6	-0.5	-0.3	-0.0	-0.6	-0.5	0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.6	-0.5	-0.2	0.2	0.0	-0.2	0.2	0.3	-0.1	0.0	-0.1	-0.2	0.2	-0.8	0.4	0.3	-0.1	0.2	-0.3	0.7	-0.2	0.1	-0.5	-0.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.9	-0.1	-0.0	0.7	0.2	-0.1	0.8	0.4	-0.0	-0.1	-0.1	0.1	-0.1	0.4	-0.4	-0.2	0.7	-0.0	0.9	0.2	0.5	0.4	0.2	-0.1	0.1
Qualifications: College or University degree	0.1	0.3	1.9	1.1	-0.7	-0.4	0.2	0.1	0.0	-0.1	-0.1	0.4	-0.1	1.1	-0.1	0.2	0.7	0.5	0.3	0.6	-0.4	0.5	0.6	0.4	0.2	1.4	0.1
Illnesses of father: Heart disease	0.1	0.2	0.7	-0.5	0.4	-0.5	-0.6	-0.1	0.3	-0.3	0.5	0.1	0.5	-0.3	0.4	0.0	0.4	0.4	0.2	0.3	-0.3	0.2	-0.8	-0.4	0.9	0.1	-0.0
Long-standing illness, disability or infirmity	0.1	0.1	0.5	-0.5	-0.2	0.5	-0.5	-0.6	0.3	0.1	-0.0	0.1	0.0	-0.1	0.0	-0.6	0.0	0.1	-0.0	-0.3	-0.1	0.2	0.4	0.3	-0.7	-0.2	0.1
Mineral and other dietary supplements	0.1	0.2	0.8	0.7	-0.5	-0.6	0.3	-0.1	-0.1	0.0	-0.3	0.3	-0.3	0.2	-0.0	-0.3	-0.0	0.5	-0.1	-0.5	-0.4	-0.1	0.5	-0.2	-0.7	0.9	-0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	1.2	-0.4	0.4	0.0	-0.5	-1.1	-0.1	-0.3	-0.0	-0.1	0.0	0.1	-0.1	0.2	0.3	-0.2	0.3	0.6	-0.2	0.3	0.2	0.0	0.7	-0.2	0.5
Average weekly beer plus cider intake	0.1	0.2	0.7	-0.5	0.6	0.2	-0.0	-0.4	0.2	0.2	0.6	0.3	0.7	-0.9	0.6	-0.2	-0.3	-0.1	0.2	-0.1	-0.4	-0.5	-0.3	-0.3	-0.8	-0.5	-0.3
Lung FEV1/FVC ratio	0.0	0.2	0.8	-0.6	0.3	0.9	-0.0	0.1	0.4	0.6	0.1	0.4	-0.1	-0.8	-0.0	-0.8	0.2	-0.5	-0.8	-0.2	-0.6	-0.0	-0.4	0.1	-0.5	-0.8	0.5
Hair Pigment	0.0	1.2	3.8	-0.2	-1.4	-0.2	-0.6	-1.4	-1.7	-0.3	-1.4	-1.3	-1.3	-0.8	-1.5	0.7	-0.8	-1.9	0.2	0.4	-1.7	-1.9	-0.2	-0.6	-0.8	-1.3	-0.2

Hub : Genes

TMEM176A

Models

Trait associations