Best TWAS P=1.75e-08 · Best GWAS P=2.39e-09 conditioned to 0.0196
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ERI1 | 0.05 | 0.00 | enet | 10 | 0.00 | 5.5e-01 | -3.4 | 5.5 | 3.0e-08 | -0.69 | 0.28 | 0.17 | FALSE |
| 2 | GTEx | Lung | AC087269.1 | 0.20 | 0.19 | lasso | 9 | 0.18 | 4.8e-14 | -4.7 | 5.2 | 1.5e-07 | -0.64 | 0.65 | 0.34 | FALSE |
| 3 | GTEx | Lung | CLDN23 | 0.18 | 0.17 | lasso | 7 | 0.16 | 2.5e-12 | -4.7 | 5.1 | 2.8e-07 | -0.63 | 0.66 | 0.33 | FALSE |
| 4 | GTEx | Nerve Tibial | ERI1 | 0.07 | 0.01 | enet | 16 | 0.01 | 4.2e-02 | 4.1 | 5.3 | 1.4e-07 | -0.78 | 0.22 | 0.41 | FALSE |
| 5 | GTEx | Testis | ERI1 | 0.30 | 0.00 | enet | 15 | 0.01 | 9.6e-02 | -4.2 | -5.3 | 8.7e-08 | 0.45 | 0.15 | 0.18 | FALSE |
| 6 | GTEx | Thyroid | AC087269.1 | 0.15 | 0.05 | lasso | 2 | 0.07 | 5.1e-06 | -4.7 | 5.3 | 1.4e-07 | -0.59 | 0.66 | 0.30 | FALSE |
| 7 | GTEx | Thyroid | CLDN23 | 0.14 | 0.03 | lasso | 2 | 0.03 | 1.1e-03 | -4.7 | 5.4 | 8.4e-08 | -0.58 | 0.40 | 0.32 | FALSE |
| 8 | NTR | Blood | MFHAS1 | 0.02 | 0.01 | blup | 759 | 0.01 | 2.9e-04 | -5.4 | -5.6 | 1.8e-08 | 0.82 | 0.08 | 0.92 | TRUE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | SGK223 | 0.16 | 0.20 | enet | 14 | 0.22 | 6.1e-21 | 4.8 | 5.3 | 1.1e-07 | -0.72 | 0.06 | 0.93 | FALSE |