Best TWAS P=7.04e-16 · Best GWAS P=9.92e-14 conditioned to 0.928
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GSDMC | 0.03 | 0.01 | blup | 57 | 0.02 | 1.4e-02 | -7.3 | -7.0 | 3.6e-12 | 0.94 | 0.01 | 0.88 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GSDMC | 0.05 | 0.06 | lasso | 7 | 0.05 | 1.5e-10 | -7.3 | -7.6 | 3.5e-14 | 0.91 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | GSDMC | 0.21 | 0.14 | blup | 57 | 0.15 | 1.2e-07 | -7.3 | -6.7 | 1.8e-11 | 0.83 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | GSDMC | 0.13 | 0.08 | lasso | 7 | 0.09 | 5.0e-06 | -6.9 | -6.8 | 1.2e-11 | 0.89 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GSDMC | 0.25 | 0.30 | lasso | 5 | 0.32 | 4.6e-36 | -7.3 | -7.3 | 2.0e-13 | 0.95 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | GSDMC | 0.09 | 0.03 | enet | 5 | 0.06 | 7.0e-08 | -6.9 | -6.3 | 3.7e-10 | 0.77 | 0.03 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GSDMC | 0.16 | 0.14 | blup | 57 | 0.15 | 6.3e-17 | -6.8 | -7.0 | 1.8e-12 | 0.86 | 0.07 | 0.93 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GSDMC | 0.03 | 0.02 | blup | 57 | 0.02 | 1.4e-03 | -7.3 | -8.1 | 7.0e-16 | 0.92 | 0.01 | 0.93 | TRUE |
| 9 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | GSDMC | 0.21 | 0.05 | blup | 57 | 0.06 | 1.2e-02 | -7.3 | -6.2 | 4.4e-10 | 0.87 | 0.01 | 0.82 | FALSE |