Best TWAS P=4.29e-09 · Best GWAS P=4.46e-11 conditioned to 0.00182
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZHX2 | 0.21 | 0.20 | lasso | 4 | 0.20 | 6.8e-63 | -4.7 | 5.7 | 1.1e-08 | 0.74 | 0.98 | 0.02 | FALSE |
2 | YFS | Blood | ZHX2 | 0.31 | 0.22 | enet | 30 | 0.25 | 1.1e-82 | -4.7 | -5.9 | 4.3e-09 | -0.81 | 0.98 | 0.02 | TRUE |