Best TWAS P=5.61e-08 · Best GWAS P=4.42e-07 conditioned to 0.0367
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | ZNF438 | 0.02 | 0.00 | bslmm | 501 | 0.01 | 3.4e-04 | 5.0 | -5.2 | 1.6e-07 | -0.72 | 0.02 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF438 | 0.03 | 0.00 | blup | 123 | 0.02 | 1.8e-05 | 4.4 | 5.4 | 5.6e-08 | 0.63 | 0.08 | 0.76 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF438 | 0.09 | 0.03 | enet | 10 | 0.03 | 7.1e-05 | 4.4 | 5.3 | 1.0e-07 | 0.76 | 0.02 | 0.95 | FALSE |