[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr10:76,664,253-80,383,574

Best TWAS P=5.1e-15 · Best GWAS P=5.82e-18 conditioned to 1.04e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Cortex	C10orf11	0.32	0.15	lasso	8	0.21	1.4e-06	7.2	-7.8	5.1e-15	0.77	0.38	0.57	TRUE
1	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-4.8	-5.7	1.2e-08	-0.04	0.02	0.96	TRUE
5	GTEx	Muscle Skeletal	C10orf11	0.11	0.13	lasso	3	0.12	5.1e-12	7.2	-7.4	9.8e-14	0.73	0.99	0.01	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	C10orf11	0.20	0.23	lasso	4	0.23	1.1e-29	7.2	-7.2	4.7e-13	0.69	1.00	0.00	FALSE
2	GTEx	Brain Caudate basal ganglia	C10orf11	0.35	0.27	lasso	4	0.25	9.8e-08	7.1	-7.2	6.8e-13	0.69	0.63	0.32	FALSE
4	GTEx	Brain Frontal Cortex BA9	C10orf11	0.33	0.18	enet	11	0.19	9.3e-06	7.1	-7.1	1.1e-12	0.70	0.47	0.38	FALSE
7	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-4.9	-5.5	3.1e-08	-0.01	0.01	0.98	FALSE
6	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-4.9	-5.4	6.4e-08	-0.01	0.02	0.98	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	DLG5	0.19	0.17	bslmm	592	0.20	1.5e-24	-4.9	-5.2	2.4e-07	0.03	0.01	0.98	FALSE