TWAS
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Models
Genes
Traits
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr10:80,443,273-81,901,722
Best TWAS P=1.4e-07 · Best GWAS P=1.32e-06 conditioned to 2.85e-06
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZCCHC24
0.12
0.01
lasso
6
0.03
0.0034
4.1
5.3
1.4e-07
0.03
0.05
0.41
TRUE