[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : ← →

chr10:74,317,852-76,323,150

Best TWAS P=5.08e-12 · Best GWAS P=9.36e-12 conditioned to 0.0632

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEC24C	0.04	0.02	blup	29	0.03	2.6e-06	6.7	6.9	5.1e-12	0.86	0.01	0.99	TRUE
1	GTEx	Adipose Visceral Omentum	DNAJC9-AS1	0.17	0.00	enet	50	0.02	1.9e-02	3.4	-6.1	8.8e-10	0.01	0.05	0.04	TRUE
9	YFS	Blood	NDST2	0.10	0.09	lasso	14	0.10	5.0e-30	6.8	-6.8	7.6e-12	-0.98	0.01	0.99	FALSE
5	GTEx	Prostate	RP11-574K11.5	0.29	0.02	enet	43	0.00	2.4e-01	5.8	-6.7	1.6e-11	-0.62	0.02	0.42	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	CHCHD1	0.02	0.01	lasso	2	0.01	2.5e-03	6.7	6.7	2.7e-11	0.94	0.01	0.94	FALSE
3	GTEx	Cells Transformed fibroblasts	CAMK2G	0.06	0.04	enet	10	0.06	2.2e-05	6.7	6.4	1.5e-10	0.88	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	SEC24C	0.02	0.01	enet	4	0.01	8.5e-03	-4.6	6.2	4.9e-10	0.50	0.05	0.16	FALSE
16	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	BMS1P4	0.21	0.08	enet	15	0.08	2.3e-03	6.6	-6.2	5.2e-10	-0.80	0.00	0.81	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	MYOZ1	0.04	0.01	blup	235	0.02	2.6e-03	-4.6	6.0	1.6e-09	0.52	0.18	0.51	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	NDST2	0.03	0.02	blup	37	0.02	3.3e-03	-4.2	-5.7	1.3e-08	-0.38	0.27	0.11	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SEC24C	0.07	0.07	blup	29	0.07	9.4e-05	-4.6	5.6	2.6e-08	0.35	0.28	0.08	FALSE
4	GTEx	Esophagus Mucosa	CAMK2G	0.10	0.04	lasso	3	0.06	4.0e-05	5.4	5.5	4.7e-08	0.82	0.08	0.84	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	BMS1P4	0.05	0.01	enet	4	0.02	8.4e-03	6.6	-5.4	7.9e-08	-0.90	0.00	0.92	FALSE
8	YFS	Blood	FUT11	0.02	0.00	bslmm	231	0.01	2.0e-03	6.7	-5.3	1.1e-07	-0.70	0.01	0.97	FALSE
2	GTEx	Artery Tibial	DUSP8P5	0.09	0.03	enet	8	0.03	2.0e-03	5.4	5.2	1.8e-07	0.80	0.22	0.49	FALSE
6	GTEx	Spleen	MRPS16	0.50	-0.01	lasso	6	0.02	1.1e-01	3.4	5.2	2.1e-07	0.08	0.01	0.05	FALSE